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  • Cabanillas, B.; Vasquez-Ocmin, P.; Zebiri, I.; Rengifo, E.; Sauvain, M.; Le, H. L.; Vaisberg, A.; Voutquenne-Nazabadioko, L.; Haddad, M. (Taylor & Francis, 2016)
    One new 5-alkylresorcinol glucoside (1) was isolated from leaves of Cybianthus magnus, along with 12 known compounds, isolated from four plants belonging to Myrsinaceae family (2, 3 isolated from C. magnus; 4–7, 10 and 11 ...
  • Vasquez-Ocmin, Pedro; Haddad, Mohamed; Gadea, Alice; Jullian, Valerie; Castillo, Denis; Paloque, Lucie; Cerapio, Juan Pablo; Bourdy, Genevieve; Sauvain, Michel (Taylor & Francis, 2016)
    One new phthalide (1) was isolated from aerial parts of Peperomia nivalis, along with known compounds (2 and 3), reported in this species for the first time. The structure of the new compound was characterised on the basis ...
  • Ponce, Reynaldo; León-Janampa, Nancy; Gilman, Robert H.; Liendo, Ruddy; Roncal, Elisa; Luis, Sueline; Quiñones-Garcia, Stefany; Silverstein, Zach; García, Hector H.; Gonzales, Armando; Sheen, Patricia; Zimic, Mirko; Pajuelo, Mónica J.; Cysticercosis Working Group in Peru (Elsevier, 2018)
    Cysticercosis is a worldwide parasitic disease of humans and pigs principally caused by infection with the larvae of the pork tapeworm Taenia solium. Through the use of the recently-made-available T. solium genome, we ...
  • Rueda, Daniel; Furukawa, Roberto; Fuentes, Patricia; Comina, Germán; Rey De Castro, Nicolás G.; Requena, David; Gilman, Robert H.; Sheen, Patricia; Zimic, Mirko (Medknow Publications, 2018)
    Introduction: Tuberculosis (TB) is a significant cause of morbidity and mortality worldwide. The patient compliance with the long treatment regimens is essential for successful eradication. Pyrazinamide (PZA) shortens these ...
  • Poterico, Julio A.; Vásquez, Flor; Chávez-Pastor, Miguel; Trubnykova, Milana; Chavesta, Félix; Chirinos, Jenny; Salcedo, Nancy; Mena, Rosmery; Cubas, Sulema; González, Rocío; Alvariño, Rossana; Abarca-Barriga, Hugo (IOS Press, 2016)
    Chromosome 18 pericentric inversion carriers could have offspring with recombinant chromosomes, leading to patients with clinical variable manifestations. Patients with 18p-/18q+ rearrangements share some clinical ...
  • Alvarez, Carolina; Verdonck, Kristien; Tipismana, Martin; Gotuzzo, Eduardo (BMJ Publishing Group, 2015)
    Human T-lymphotropic virus 1 (HTLV-1) is frequent in Peru; an estimated 1–2% of the Peruvian population carry this retrovirus. HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic disabling ...
  • Althoff, Keri-N.; Rebeiro, Peter-F.; Hanna, David-B.; Padgett, Denis; Horberg, Michael-A.; Grinsztejn, Beatriz; Abraham, Alison-G.; Hogg, Robert; Gill, M. John; Wolff, Marcelo-J.; Mayor, Angel; Rachlis, Anita; Williams, Carolyn; Sterling, Timothy-R.; Kitahata, Mari-M.; Buchacz, Kate; Thorne, Jennifer-E.; Cesar, Carina; Cordero, Fernando-M.; Rourke, Sean-B.; Sierra-Madero, Juan; Pape, Jean-W.; Cahn, Pedro; McGowan, Catherine (Wiley, 2016)
    INTRODUCTION: Maps are powerful tools for visualization of differences in health indicators by geographical region, but multi-country maps of HIV indicators do not exist, perhaps due to lack of consistent data across ...
  • Arias, Cesar A.; Reyes, Jinnethe; Carvajal, Lina Paola; Rincon, Sandra; Diaz, Lorena; Panesso, Diana; Ibarra, Gabriel; Rios, Rafael; Munita, Jose M.; Salles, Mauro J.; Alvarez-Moreno, Carlos; Labarca, Jaime; Garcia, Coralith; Luna, Carlos M.; Mejia-Villatoro, Carlos; Zurita, Jeannete; Guzman-Blanco, Manuel; Rodriguez-Noriega, Eduardo; Narechania, Apurva; Rojas, Laura J.; Planet, Paul J.; Weinstock, George M.; Gotuzzo, Eduardo; Seas, Carlos (American Society of Microbiology, 2017)
    Staphylococcus aureus is an important pathogen causing a spectrum of diseases ranging from mild skin and soft tissue infections to life-threatening conditions. Bloodstream infections are particularly important, and the ...
  • Otero, Larissa; Shah, Lena; Verdonck, Kristien; Battaglioli, Tullia; Brewer, Timothy; Gotuzzo, Eduardo; Seas, Carlos; Van-der-Stuyft, Patrick (BMC, 2016)
    BACKGROUND: Household contacts (HHCs) of TB cases are at increased risk for TB disease compared to the general population but the risk may be modified by individual or household factors. We conducted a study to determine ...
  • Meinzen, Christopher; Proano, Alvaro; Gilman, Robert-H.; Caviedes, Luz; Coronel, Jorge; Zimic, Mirko; Sheen, Patricia (Elsevier, 2016)
    BACKGROUND: Pyrazinamide (PZA) is the most important drug against the latent stage of tuberculosis (TB) and is used in both first and second line treatment regimens. The continued increase in multi-drug resistant TB and ...
  • Wingfield, Tom; Tovar, Marco A.; Huff, Doug; Boccia, Delia; Montoya, Rosario; Ramos, Eric; Datta, Sumona; Saunders, Matthew J.; Lewis, James J.; Gilman, Robert H.; Evans, Carlton A. (World Health Organization, 2017)
    OBJECTIVE: To evaluate the impact of socioeconomic support on tuberculosis preventive therapy initiation in household contacts of tuberculosis patients and on treatment success in patients. METHODS: A non-blinded, ...
  • Kline, L.; Jones-Smith, J.; Jaime Miranda, J.; Pratt, M.; Reis, R. S.; Rivera, J. A.; Sallis, J. F.; Popkin, B. M. (Wiley, 2017)
    Childhood obesity rates in Latin America are among the highest in the world. This paper examines and evaluates the many efforts underway in the region to reduce and prevent further increases in obesity, identifies and ...
  • Zammarchi, Lorenzo; Casadei, Gianluigi; Strohmeyer, Marianne; Bartalesi, Filippo; Liendo, Carola; Matteelli, Alberto; Bonati, Maurizio; Gotuzzo, Eduardo; Bartoloni, Alessandro (BMC, 2015)
    BACKGROUND: In low-incidence countries, most tuberculosis (TB) cases occur among migrants and are caused by reactivation of latent tuberculosis infection (LTBI) acquired in the country of origin. Diagnosis and treatment ...
  • Saunders, Matthew J.; Wingfield, Tom; Tovar, Marco A.; Baldwin, Matthew R.; Datta, Sumona; Zevallos, Karine; Montoya, Rosario; Valencia, Teresa R.; Friedland, Jon S.; Moulton, Larry H.; Gilman, Robert H.; Evans, Carlton A. (Elsevier, 2017)
    BACKGROUND: Contacts of tuberculosis index cases are at increased risk of developing tuberculosis. Screening, preventive therapy, and surveillance for tuberculosis are underused interventions in contacts, particularly ...
  • Elraiyah, Tarig; Tsapas, Apostolos; Prutsky, Gabriela; Domecq, Juan-Pablo; Hasan, Rim; Firwana, Belal; Nabhan, Mohammed; Prokop, Larry; Hingorani, Anil; Claus, Paul-L.; Steinkraus, Lawrence-W.; Murad, Mohammad-Hassan (Elsevier, 2016)
    BACKGROUND: Multiple adjunctive therapies have been proposed to accelerate wound healing in patients with diabetes and foot ulcers. The aim of this systematic review is to summarize the best available evidence supporting ...
  • Elraiyah, Tarig; Domecq, Juan-Pablo; Prutsky, Gabriela; Tsapas, Apostolos; Nabhan, Mohammed; Frykberg, Robert-G.; Hasan, Rim; Firwana, Belal; Prokop, Larry-J.; Murad, Mohammad-Hassan (Elsevier, 2016)
    BACKGROUND: Several methods of debridement of diabetic foot ulcers are currently used. The relative efficacy of these methods is not well established. METHODS: This systematic review and meta-analysis was conducted to ...
  • Spencer-Bonilla, Gabriela; Ponce, Oscar J.; Rodriguez-Gutierrez, Rene; Alvarez-Villalobos, Neri; Erwin, Patricia J.; Larrea-Mantilla, Laura; Rogers, Anne; Montori, Victor M. (BMJ Publishing Group, 2017)
    OBJECTIVES: In the care of patients with type 2 diabetes, self-management is emphasised and studied while theory and observations suggest that patients also benefit from social support. We sought to assess the effect of ...
  • Levey, Elizabeth J.; Gelaye, Bizu; Bain, Paul; Rondon, Marta B.; Borba, Christina P. C.; Henderson, David C.; Williams, Michelle A. (Elsevier, 2017)
    Child abuse is a global problem, and parents with histories of childhood abuse are at increased risk of abusing their offspring. The objective of this systematic review is to provide a clear overview of the existing ...
  • Pizzitutti, Francesco; Pan, William; Barbieri, Alisson; Miranda, J. Jaime; Feingold, Beth; Guedes, Gilvan R.; Alarcon-Valenzuela, Javiera; Mena, Carlos F. (BMC, 2015)
    BACKGROUND: The Amazon environment has been exposed in the last decades to radical changes that have been accompanied by a remarkable rise of both Plasmodium falciparum and Plasmodium vivax malaria. The malaria transmission ...
  • Gustafsson, Mika; Gawel, Danuta R.; Alfredsson, Lars; Baranzini, Sergio; Bjorkander, Janne; Blomgran, Robert; Hellberg, Sandra; Eklund, Daniel; Ernerudh, Jan; Kockum, Ingrid; Konstantinell, Aelita; Lahesmaa, Riita; Lentini, Antonio; Liljenstrom, H. Robert I.; Mattson, Lina; Matussek, Andreas; Mellergard, Johan; Mendez, Melissa; Olsson, Tomas; Pujana, Miguel A.; Rasool, Omid; Serra-Musach, Jordi; Stenmarker, Margaretha; Tripathi, Subhash; Viitala, Miro; Wang, Hui; Zhang, Huan; Nestor, Colm E.; Benson, Mikael (American Association for the Advancement of Science, 2015)
    Early regulators of disease may increase understanding of disease mechanisms and serve as markers for presymptomatic diagnosis and treatment. However, early regulators are difficult to identify because patients generally ...

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