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  • Cysticercosis of the central nervous system: How should it be managed? 
    García Lescano, Héctor Hugo; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh (Wolters Kluwer Health, 2011)
    Purpose of Review: Taenia solium neurocysticercosis (NCC) has been long recognized as an important cause of neurological morbidity in most of the world. Unwarranted generalization of diagnostic and treatment recommendations ...
  • Cysticidal Efficacy of Combined Treatment With Praziquantel and Albendazole for Parenchymal Brain Cysticercosis 
    García Lescano, Héctor Hugo; Lescano Guevara, Andres Guillermo; Gonzales, Isidro; Bustos Palomino, Javier Arturo; Pretell, E. Javier; Horton, John; Saavedra Pastor, Herbert; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh (Oxford University Press, 2016)
    Background. The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 ...
  • CystiHuman: A model of human neurocysticercosis 
    Bonnet, G.; Pizzitutti, F.; Gonzales-Gustavson, E.A.; Gabriël, S.; Pan, W.K.; García Lescano, Héctor Hugo; Bustos Palomino, Javier Arturo; Vilchez Barreto, Percy Mcquen; ONeal, Seth E. (Public Library of Science, 2022)
    Introduction The Taenia solium tapeworm is responsible for cysticercosis, a neglected tropical disease presenting as larvae in the body of a host following taenia egg ingestion. Neurocysticercosis (NCC), the name of the ...
  • Cystoisospora and Cyclospora 
    Legua, Pedro; Seas Ramos, Carlos Rafael (Wolters Kluwer Health, 2013)
    Purpose of review: The present review focuses on recent epidemiological and diagnostic advances in cystoisosporiasis and cyclosporiasis. Recent findings: Continuous outbreaks of these parasites occur worldwide. Sporadic ...
  • Cytochrome P450 2C19 poor metabolizer phenotype in treatment resistant depression: Treatment and diagnostic implications 
    Veldic, Marin; Ahmed, Ahmed T.; Blacker, Caren J.; Geske, Jennifer R.; Biernacka, Joanna M.; Borreggine, Kristin L.; Moore, Katherine M.; Prieto, Miguel L.; Vande Voort, Jennifer L.; Croarkin, Paul E.; Hoberg, Astrid A.; Kung, Simon; Alarcón, Renato D.; Keeth, Nicola; Singh, Balwinder; Bobo, William V.; Frye, Mark A. (Frontiers Media, 2019)
    Background: Pharmacogenomic testing, specifically for pharmacokinetic (PK) and pharmacodynamic (PD) genetic variation, may contribute to a better understanding of baseline genetic differences in patients seeking treatment ...
  • Cytokine expression in Treponema pallidum infection 
    Kojima, N.; Siebert, J. C.; Maecker, H.; Rosenberg-Hasson, Y.; León Sandoval, Segundo Ramos; Vargas Rivera, Silver Keith; Konda, K. A.; Caceres Palacios, Carlos Fernando; Klausner, J. D. (BioMed Central, 2019)
    Background. Current syphilis tests cannot distinguish between active and past syphilis among patients with serofast rapid plasma reagin (RPR) titers. We investigated whether cytokine profiles might provide insight in the ...
  • Cytokines and t-lymphocyte count in patients in the acute and chronic phases of bartonella bacilliformis infection in an endemic area in Peru: A pilot study 
    Huarcaya, E.; Best, I.; Rodriguez-Tafur, J.; Maguiña Vargas, Ciro; Solórzano, N.; Menacho, J.; Lopez de Guimaraes, D.; Chauca, J.; Ventosilla, P. (Instituto de Medicina Tropical de São Paulo, 2011)
    Human Bartonellosis has an acute phase characterized by fever and hemolytic anemia, and a chronic phase with bacillary angiomatosis-like lesions. This cross-sectional pilot study evaluated the immunology patterns using ...
  • Cytokines expression in alpacas and llamas exposed to cold stress 
    Arias, Nino; Velapatino, Billie; Hung, Armando; Cok, Jaime (Elsevier, 2016)
    Cytokine expression could play an important role in camelids exposed to cold stress and subsequent pneumonia associated infections, therefore inducing a broad array of inflammatory mediators. To understand the host innate ...
  • Cytotoxic and anti-infective phenolic compounds isolated from Mikania decora and Cremastosperma microcarpum 
    Aponte, J.C.; Jin, Z.; Vaisberg Wollach, Abraham Jaime; Castillo Pareja, Denis Helan; Málaga, E.; Lewis, W.H.; Sauvain, Michel Henri Auguste; Gilman, Robert Hugh; Hammond, G.B. (Georg Thieme Verlag, 2011)
    An anticancer-bioassay guided isolation of the ethanol extract and fractions of two plants from the Peruvian rainforest, Mikania decora and Cremastosperma microcarpum, led to the characterization of one abundant diterpene, ...
  • Daily smoking and 4-year caries increment in Finnish adults 
    Bernabé, Eduardo; Delgado-Angulo, Elsa K.; Vehkalahti, Miira M.; Aromaa, Arpo; Suominen, Anna L. (Wiley, 2014)
    Objectives: Although the harmful effects of smoking on periodontal disease and oral cancer are now indisputable, its effect on dental caries is less well known. This study assessed whether daily smoking predicts caries ...
  • Danger in the Canopy. Comparative Proteomics and Bioactivities of the Venoms of the South American Palm Pit Viper Bothrops bilineatus Subspecies bilineatus and smaragdinus and Antivenomics of B. b. bilineatus (Rondônia) Venom against the Brazilian Pentabothropic Antivenom 
    Sanz, L.; Quesada-Bernat, S.; Pérez, Alicia; De Morais-Zani, K.; SantEänna, S.S.; Hatakeyama, D.M.; Tasima, L.J.; De Souza, M.B.; Kayano, A.M.; Zavaleta Martinez-Vargas, Alfonso; Salas, M.; Soares, A.M.; Calderón, L.D.A.; Tanaka-Azevedo, A.M.; Lomonte, B.; Calvete, J.J.; Caldeira, C.A.S. (American Chemical Society, 2020)
    We report a structural and functional proteomics characterization of venoms of the two subspecies (Bothrops bilineatus bilineatus and B. b. smaragdinus) of the South American palm pit viper from the Brazilian state of ...
  • The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics 
    Wheeler, D.C.; Stefansson, B.V.; Batiushin, M.; Bilchenko, O.; Cherney, D.Z.I.; Chertow, G.M.; Douthat, W.; Dwyer, J.P.; Escudero, E.; Pecoits-Filho, R.; Furuland, H.; Górriz, J.L.; Greene, T.; Haller, H.; Hou, F.F.; Kang, S.-W.; Isidto, R.; Khullar, D.; Mark, P.B.; McMurray, J.J.V.; Kashihara, N.; Nowicki, M.; Persson, F.; Correa-Rotter, R.; Rossing, P.; Toto, R.D.; Umanath, K.; Van Bui, P.; Wittmann, I.; Lindberg, M.; Sjöström, C.D.; Langkilde, A.M.; Heerspink, H.J.L. (Oxford University Press, 2020)
    BACKGROUND: The Dapagliflozin and Prevention of Adverse outcomes in Chronic Kidney Disease (DAPA-CKD; NCT03036150) trial was designed to assess the effect of the sodium-glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin ...
  • Daphnanes diterpenes from the latex of Hura crepitans L. And activity against human colorectal cancer cells Caco-2 
    Trinel, M.; Le Lamer, A.-C.; Jullian, V.; Jacquemin, D.; Graton, J.; Cristofoli, V.; Crossay, E.; Yassine, M.; Rolland, C.; Vergnolle, N.; Mejia, K.; Cabanillas Amado, Billy Joel; Racaud-Sultan, C.; Fabre, N. (Elsevier, 2020)
    Hura crepitans (Euphorbiaceae) is a tree from South America that produces an irritant latex used as a fish poison. A bio-guided fractionation of an ethanolic extract of the latex led to the isolation and structural ...
  • Daphnanes diterpenes from the latex of Hura crepitans L. and their PKCζ-dependent anti-proliferative activity on colorectal cancer cells. 
    Crossay, Elise; Jullian, Valérie; Trinel, Manon; Sagnat, David; Hamel, Dimitri; Groppi, Emie; Rolland, Corinne; Stigliani, Jean-Luc; Mejia, Kember; Cabanillas Amado, Billy Joel; Alric, Laurent; Buscail, Etienne; El Kalamouni, Chaker; Mavingui, Patrick; Deraison, Céline; Racaud-Sultan, Claire; Fabre, Nicolas (Elsevier, 2023)
    Hura crepitans L. (Euphorbiaceae) is a thorn-covered tree widespread in South America, Africa and Asia which produces an irritating milky latex containing numerous secondary metabolites, notably daphnane-type diterpenes ...
  • Dark Adaptation at High Altitude: An Unexpected Pupillary Response to Chronic Hypoxia in Andean Highlanders 
    Healy, Katherine; Labrique, Alain B.; Miranda, J. Jaime; Gilman, Robert Hugh; Danz, David; Davila-Roman, Victor G.; Huicho Oriundo, Luis; León-Velarde, Fabiola; Checkley, William (Mary Ann Liebert, 2016)
    Healy, Katherine, Alain B. Labrique, J. Jaime Miranda, Robert H. Gilman, David Danz, Victor G. Davila-Roman, Luis Huicho, Fabiola Leon-Velarde, and William Checkley. Dark adaptation at high altitude: an unexpected pupillary ...
  • Data do count! Collection and use of maternal mortality data in Peru, 1990-2005, and improvements since 2005 
    Iguiñiz Romero, Ruth Anunciación; Palomino, N. (Taylor and Francis, 2012)
    This paper reports on a qualitative, exploratory study in 2005, based on interviews with 15 key decision-makers from the Peruvian Ministry of Health responsible for maternal mortality prevention and officials responsible ...
  • Data integrity–based methodology and checklist for identifying implementation risks of physiological sensing in mobile health projects: Quantitative and qualitative analysis 
    Zhang, J.; Tüshaus, L.; Martínez, N.N.; Moreo, M.; Verástegui Huasasquiche, Héctor Alfredo; Hartinger Peña, Stella Maria; Mäusezahl, D.; Karlen, W. (JMIR Publications, 2018)
    Background: Mobile health (mHealth) technologies have the potential to bring health care closer to people with otherwise limited access to adequate health care. However, physiological monitoring using mobile medical sensors ...
  • Data mining of DNA sequences submitted by Peruvian institutions to public genetic databases 
    Romero, P.E.; Castillo-Vilcahuaman, C. (Facultad de Ciencias Biológicas. Universidad Nacional Mayor de San Marcos, 2021)
    Genetic diversity is an important component of biodiversity, and it is crucial for current efforts to protect and sustainably manage several organisms and habitats. As far as we know, there is only one work describing ...
  • Data pooling efforts in Africa and Latin America 
    Carrillo Larco, Rodrigo Martín; Miranda, J. Jaime; Kengne, Andre P. (Elsevier, 2017)
    In August, 2016, the Global Body-Mass Index (BMI) Mortality Collaboration1 published their work on BMI as a predictor of all-cause mortality. The investigators pooled individual participant data from 239 prospective studies, ...
  • Data-driven methods distort optimal cutoffs and accuracy estimates of depression screening tools: a simulation study using individual participant data 
    Bhandari, Parash Mani; Levis, Brooke; Neupane, Dipika; Patten, Scott B.; Shrier, Ian; Thombs, Brett D.; Benedetti, Andrea (Elsevier, 2021)
    OBJECTIVE: To evaluate, across multiple sample sizes, the degree that data-driven methods result in (1) optimal cutoffs different from population optimal cutoff and (2) bias in accuracy estimates. STUDY DESIGN AND SETTING: ...

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