Listar por tema "drug safety"

Ordenar por:Orden:Resultados:

  • Antifibrinolytic therapy to reduce haemoptysis from any cause 
    Prutsky, Gabriela; Pablo Domecq, Juan; Salazar, Carlos A.; Accinelli Tanaka, Roberto Alfonso (Cochrane Collaboration, 2012)
    Background: Haemoptysis is a common pathology around the world, occurring with more frequency in low-income countries. It has different etiologies, many of which have infectious characteristics. Antifibrinolytic agents are ...
  • Body composition and quality of life in adults treated with GH therapy: A systematic review and meta-analysis 
    Hazem, A.; Elamin, M.B.; Bancos, I.; Málaga Rodríguez, Germán Javier; Prutsky, G.; Domecq, J.P.; Elraiyah, T.A.; Abu Elnour, N.O.; Prevost Ruiz, Yolanda; PAlmandoz, J.; Zeballos-Palacios, C.; Velasquez, E.R.; Erwin, P.J.; Natt, N.; Montori, V.M.; Murad, M.H. (BioScientifica, 2012)
    Objective: To summarise the evidence about the efficacy and safety of using GH in adults with GH deficiency focusing on quality of life and body composition. Data sources: We searched MEDLINE, EMBASE, Cochrane CENTRAL, Web ...
  • Clonidine in patients undergoing noncardiac surgery 
    Devereaux, P.J.; Sessler, D.I.; Leslie, K.; Kurz, A.; Mrkobrada, M.; Alonso-Coello, P.; Villar, J.C.; Sigamani, A.; Biccard, B.M.; Meyhoff, C.S.; Parlow, J.L.; Guyatt, G.; Robinson, A.; Garg, A.X.; Rodseth, R.N.; Botto, F.; Lurati Buse, G.; Xavier, D.; Chan, M.T.V.; Tiboni, M.; Cook, D.; Kumar, P.A.; Forget, P.; Málaga Rodríguez, Germán Javier; Fleischmann, E.; Amir, M.; Eikelboom, J.; Mizera, R.; Torres, D.; Wang, C.Y.; VanHelder, T.; Paniagua, P.; Berwanger, O.; Srinathan, S.; Graham, M.; Pasin, L.; Le Manach, Y.; Gao, P.; Pogue, J.; Whitlock, R.; Lamy, A.; Kearon, C.; Chow, C.; Pettit, S.; Chrolavicius, S.; Yusuf, S. (Massachusetts Medical Society, 2014)
    BACKGROUND: Marked activation of the sympathetic nervous system occurs during and after non-cardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may prevent perioperative myocardial infarction and ...
  • Corticosteroid use in neurocysticercosis 
    Nash, T.E.; Mahanty, S.; García Lescano, Héctor Hugo (Taylor and Francis, 2011)
    The cystic larvae of Taenia solium commonly infect the human nervous system, resulting in neurocysticercosis, a major contributor to seizure disorders in most of the world. Inflammation around the parasites is a hallmark ...
  • Cystic echinococcosis: Chronic, complex, and still neglected 
    Brunetti, E.; García Lescano, Héctor Hugo; Junghanss, T. (Public Library of Science, 2011)
    Cystic echinococcosis (CE), an infection with the larval form of the dog tapeworm Echinococcus granulosus, still causes serious lung and liver disease with a worldwide geographical distribution. This parasitic infection ...
  • Cytochrome P450 2C19 poor metabolizer phenotype in treatment resistant depression: Treatment and diagnostic implications 
    Veldic, Marin; Ahmed, Ahmed T.; Blacker, Caren J.; Geske, Jennifer R.; Biernacka, Joanna M.; Borreggine, Kristin L.; Moore, Katherine M.; Prieto, Miguel L.; Vande Voort, Jennifer L.; Croarkin, Paul E.; Hoberg, Astrid A.; Kung, Simon; Alarcón, Renato D.; Keeth, Nicola; Singh, Balwinder; Bobo, William V.; Frye, Mark A. (Frontiers Media, 2019)
    Background: Pharmacogenomic testing, specifically for pharmacokinetic (PK) and pharmacodynamic (PD) genetic variation, may contribute to a better understanding of baseline genetic differences in patients seeking treatment ...
  • Drugs commonly associated with weight change: A systematic review and meta-analysis 
    Domecq, J.P.; Prutsky, G.; Leppin, A.; Sonbol, M.B.; Altayar, O.; Undavalli, C.; Wang, Z.; Elraiyah, T.; Brito, J.P.; Mauck, K.F.; Lababidi, M.H.; Prokop, L.J.; Asi, N.; Wei, J.; Fidahussein, S.; Montori, V.M.; Murad, M.H. (Oxford University Press, 2015)
    Context: Various drugs affect body weight as a side effect. Objective: We conducted this systematic review and meta-analysis to summarize the evidence about commonly prescribed drugs and their association with weight change. ...
  • Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands. 
    Gonzales Rengifo, Gustavo Francisco (Hindawi, 2012)
    Lepidium meyenii (maca) is a Peruvian plant of the Brassicaceae family cultivated for more than 2000 years, which grows exclusively in the central Andes between 4000 and 4500 m altitude. Maca is used as a food supplement ...
  • Influenza vaccines licensed in the United States in healthy children: A systematic review and network meta-analysis (Protocol) 
    Prutsky, G.J.; Domecq, J.P.; Elraiyah, T.; Wang, Z.; Grohskopf, L.A.; Prokop, L.J.; Montori, V.M.; Murad, M.H. (BioMed Central, 2012)
    Background: Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for prevention methods, including vaccination. While ...
  • Latin American algorithm for treatment of relapsing-remitting multiple sclerosis using disease-modifying agents 
    Finkelsztejn, A.; Gabbai, A.A.; Fragoso, Y.D.; Carrá, A.; Macías-Islas, M.A.; Arcega-Revilla, R.; García-Bonitto, J.; Oehninger-Gatti, C.L.; Orozco-Escobar, G.; Tarulla, A.; Vergara, F.; Vizcarra-Escobar, Darwin (SP Academia Brasileira de Neurologia, 2012)
    Objective: It is estimated that circa 50,000 individuals have relapsing-remitting multiple sclerosis in Latin America. European and NorthAmerican algorithms for the treatment of multiple sclerosis do not foresee our regional ...
  • Long-Term Efficacy and Safety of Biosimilar CT-P10 Versus Innovator Rituximab in Rheumatoid Arthritis: 48-Week Results from a Randomized Phase III Trial 
    Suh, Chang-Hee; Yoo, Dae Hyun; Berrocal Kasay, Alfredo; Chalouhi El-Khouri, Elia; Cons Molina, Francisco Fidenci; Shesternya, Pavel; Miranda, Pedro; Medina-Rodriguez, Francisco G.; Wiland, Piotr; Jeka, Slawomir; Chavez-Corrales, Jose; Linde, Thomas; Hrycaj, Pawel; Abello-Banfi, Mauricio; Hospodarskyy, Ihor; Jaworski, Janusz; Piotrowski, Mariusz; Brzosko, Marek; Krogulec, Marek; Shevchuk, Sergii; Calvo, Armando; Andersone, Daina; Park, Won; Shim, Seung Cheol; Lee, Sang Joon; Lee, Sung Young (Springer, 2019)
    Objective: The aim of this study was to investigate long-term clinical outcomes of extended treatment with CT-P10, a rituximab biosimilar, compared with rituximab reference products sourced from the USA and the EU (US-RTX ...
  • Multidrug-resistant tuberculosis and culture conversion with bedaquiline 
    Diacon, Andreas H.; Pym, Alexander; Grobusch, Martin P.; De Los Rios, Jorge M.; Gotuzzo Herencia, José Eduardo; Vasilyeva, Irina; Leimane, Vaira; Andries, Koen; Bakare, Nyasha; De Marez, Tine; Haxaire-Theeuwes, Myriam; Lounis, Nacer; Meyvisch, Paul; De Paepe, Els; Van Heeswijk, Rolf P.G.; Dannemann, Brian (Massachusetts Medical Society, 2014)
    BACKGROUND: Bedaquiline (Sirturo, TMC207), a diarylquinoline that inhibits mycobacterial ATP synthase, has been associated with accelerated sputum-culture conversion in patients with multidrug-resistant tuberculosis, when ...
  • Oxfendazole: a promising agent for the treatment and control of helminth infections in humans. 
    Gonzalez Zariquiey, Armando Emiliano; Codd, Ellen E.; Horton, John; García Lescano, Héctor Hugo; Gilman, Robert Hugh (Taylor and Francis, 2018)
    Introduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl] carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite fenbendazole also has anthelminthic action. A very limited ...
  • Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: A randomized, placebo-controlled first-inhuman single-dose escalation study 
    An, G.; Murry, D.J.; Gajurel, K.; Bach, T.; Deye, G.; Stebounova, L.V.; Codd, E.E.; Horton, J.; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; Ince, D.; Hodgson-Zingman, D.; Nomicos, E.Y.H.; Conrad, T.; Kennedy, J.; Jones, W.; Gilman, Robert Hugh; Winokur, P. (American Society for Microbiology, 2019)
    Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of ...
  • Practical Issues Concerning the Approval and Use of Biosimilar Drugs for the Treatment of Multiple Sclerosis in Latin America 
    Steinberg, Judith; Fragoso, Yara D.; Duran Quiroz, Juan Carlos; Garcia, Juan Raul; Guerra, Caroline; Rodriguez, Virginia; Carcamo Rodriguez, Claudia; Ciampi, Ethel; Correa-Diaz, Edgar; Macias, Miguel; Novarro, Nelson; Vizcarra-Escobar, Darwin; Oehninger Gatti, Carlos; Orozco, Geraldine; Carra, Adriana (Springer, 2019)
    The use of biosimilar drugs for multiple sclerosis (MS) has become widespread in Latin America, with the goal of reducing costs of treatments, promoting the sustainability of healthcare systems, and improving patient ...
  • Resistant Gram-negative infections in the outpatient setting in Latin America 
    Salles, M.J.C.; Zurita, J.; Mejía, C.; Villegas, M.V.; Alvarez, C.; Bavestrello, L.; Berezin, E.; Gotuzzo Herencia, José Eduardo; Guzmán-Blanco, M.; Labarca, J.A.; Luna, C.M.; Nouer, S.; Rodríguez-Noriega, E.; Seas Ramos, Carlos Rafael (Cambridge University Press, 2013)
    Latin America has a high rate of community-associated infections caused by multidrug-resistant Enterobacteriaceae relative to other world regions. A review of the literature over the last 10 years indicates that urinary ...
  • Single-dose tafenoquine to prevent relapse of plasmodium vivax malaria 
    Lacerda, M.V.G.; Llanos Cuentas, Elmer Alejandro; Krudsood, S.; Lon, C.; Saunders, D.L.; Mohammed, R.; Yilma, D.; Pereira, D.B.; Espino, F.E.J.; Mia, R.Z.; Chuquiyauri, R.; Val, F.; Casapía, M.; Monteiro, W.M.; Brito, M.A.M.; Costa, M.R.F.; Buathong, N.; Noedl, H.; Diro, E.; Getie, S.; Wubie, K.M.; Abdissa, A.; Zeynudin, A.; Abebe, C.; Tada, M.S.; Brand, F.; Beck, H.-P.; Angus, B.; Duparc, S.; Kleim, J.-P.; Kellam, L.M.; Rousell, V.M.; Jones, S.W.; Hardaker, E.; Mohamed, K.; Clover, D.D.; Fletcher, K.; Breton, J.J.; Ugwuegbulam, C.O.; Green, J.A.; Koh, G.C.K.W. (Massachusetts Medical Society, 2019)
    BACKGROUND: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed "radical cure"). Tafenoquine ...
  • Tafenoquine versus primaquine to prevent relapse of plasmodium vivax malaria 
    Llanos Cuentas, Elmer Alejandro; Lacerda, M.V.G.; Hien, T.T.; Vélez, I.D.; Namaik-Larp, C.; Chu, C.S.; Villegas, M.F.; Val, F.; Monteiro, W.M.; Brito, M.A.M.; Costa, M.R.F.; Chuquiyauri, R.; Casapía, M.; Nguyen, C.H.; Aruachan, S.; Papwijitsil, R.; Nosten, F.H.; Bancone, G.; Angus, B.; Duparc, S.; Craig, G.; Rousell, V.M.; Jones, S.W.; Hardaker, E.; Clover, D.D.; Kendall, L.; Mohamed, K.; Koh, G.C.K.W.; Wilches, V.M.; Breton, J.J.; Green, J.A. (Massachusetts Medical Society, 2019)
    BACKGROUND: Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed "radical cure." METHODS: We ...
  • Tocilizumab in COVID-19: Enthusiasm vs. evidence 
    Zena-Huancas, P.; Leon-Jimenez, F.; Bryce-Alberti, M.; Portmann Baracco, Arianna Sibila (Wolters Kluwer Health, 2021)
    Based on the pathophysiological characterization of COVID-19, initial studies suggested the use of tocilizumab (TCZ), a recombinant humanized monoclonal antibody of the immunoglobulin G1 class, for management of the cytokine ...
  • The Use of Probiotics in Pediatric Gastroenterology: A Review of the Literature and Recommendations by Latin-American Experts 
    Cruchet, S.; Furnes, R.; Maruy, A.; Hebel, E.; Palacios, J.; Medina, Fernando; Ramirez, N.; Orsi, M.; Rondon, L.; Sdepanian, V.; Xóchihua, L.; Ybarra, M.; Zablah, R.A. (Springer, 2015)
    Objective: The stability and composition of intestinal flora plays a vital role in human wellbeing throughout life from as early as birth. Over the past 50 years, several studies have been conducted to evaluate the effect ...

Buscar en el Repositorio

Listar

Panel de Control