Listar por tema "nucleotide sequence"

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  • Ascorbic acid has superior ex vivo antiproliferative, cell death-inducing and immunomodulatory effects over IFN-α in HTLV-1-associated myelopathy 
    Moens, B.; Decanine, D.; Menezes, S.M.; Khouri, R.; Silva-Santos, G.; Lopez, G.; Alvarez, C.; Talledo Albujar, Michael John; Gotuzzo Herencia, José Eduardo; de Almeida Kruschewsky, R.; Galvão-Castro, B.; Vandamme, A.-M.; van Weyenbergh, J. (Public Library of Science, 2012)
    Background: Clear therapeutic guidelines for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are missing due to the lack of randomized double-blind controlled clinical trials. Moderate yet similar ...
  • Biologic responses of bacteria communities living at the mucus secretion of common carp (Cyprinus carpio) after exposure to the carbon nanomaterial fullerene (C 60) 
    Letts, R.E.; Pereira, T.C.B.; Bogo, M.R.; Monserrat, J.M. (Springer, 2011)
    Bacteria communities living in mucus secretions of common carp Cyprinus carpio (Cyprinidae) were exposed to the organic nanomaterial fullerene (C60) to evaluate its potential bactericidal effects. End points analyzed were ...
  • Circulating T cell-monocyte complexes are markers of immune perturbations. 
    Burel, Julie G.; Pomaznoy, Mikhail; Lindestam Arlehamn, Cecilia S.; Weiskopf, Daniela; da Silva Antunes, Ricardo; Jung, Yunmin; Babor, Mariana; Schulten, Veronique; Seumois, Gregory; Greenbaum, Jason A.; Premawansa, Sunil; Premawansa, Gayani; Wijewickrama, Ananda; Vidanagama, Dhammika; Gunasena, Bandu; Tippalagama, Rashmi; deSilva, Aruna D.; Gilman, Robert Hugh; Saito, Mayuko; Taplitz, Randy; Ley, Klaus; Vijayanand, Pandurangan; Sette, Alessandro; Peters, Bjoern (eLife Sciences Publications, 2019)
    Our results highlight for the first time that a significant proportion of cell doublets in flow cytometry, previously believed to be the result of technical artifacts and thus ignored in data acquisition and analysis, are ...
  • Comparative gene expression analysis throughout the life cycle of Leishmania braziliensis: Diversity of expression profiles among clinical isolates 
    Adaui, V.; Castillo Pareja, Denis Helan; Zimic-Peralta, Mirko Juan; Gutierrez, Andrés; Decuypere, S.; Vanaerschot, M.; de Doncker, S.; Schnorbusch, K.; Maes, I.; van der Auwera, G.; Maes, L.; Llanos Cuentas, Elmer Alejandro; Arévalo Zelada, Jorge Luis; Dujardin, J.-C. (Public Library of Science, 2011)
    Background: Most of the Leishmania genome is reported to be constitutively expressed during the life cycle of the parasite, with a few regulated genes. Inter-species comparative transcriptomics evidenced a low number of ...
  • Complete genome sequence of bartonella bacilliformis strain KC584 (ATCC 35686) 
    Dichter, Alexander A.; Schultze, Tilman G.; Becker, Sabrina A.; Tsukayama Cisneros, Pablo; Kempf, Volkhard A. J. (American Society for Microbiology, 2020)
    Bartonella bacilliformis is the biological agent of Carrion's disease, a vector-borne, life-threatening human bartonellosis restricted to South America. Here, we report the complete genome sequence of B. bacilliformis KC584 ...
  • Evolution of the Leishmania braziliensis species complex from amplified fragment length polymorphisms, and clinical implications 
    Odiwuor, S.; Veland, N.; Maes, I.; Arévalo Zelada, Jorge Luis; Dujardin, J.-C.; Van der Auwera, G. (Elsevier, 2012)
    In order to get more insight into its evolution and geographical distribution, we investigated the Leishmania (Viannia) braziliensis species complex using amplified fragment length polymorphisms and sequencing of a heat-shock ...
  • Expression of sialic acids and other nonulosonic acids in Leptospira 
    Ricaldi, J.N.; Matthias, M.A.; Vinetz, Joseph Michael; Lewis, A.L. (BioMed Central, 2012)
    Background: Sialic acids are negatively charged nine carbon backbone sugars expressed on mammalian cell surfaces. Sialic acids are part of a larger family of nonulosonic acid (NulO) molecules that includes pseudaminic and ...
  • Infection of Domestic Dogs in Peru by Zoonotic Bartonella Species: A Cross-Sectional Prevalence Study of 219 Asymptomatic Dogs 
    Diniz, Pedro Paulo V.P.; Morton, Bridget A.; Tngrian, Maryam; Kachani, Malika; Barrón, Eduardo A.; Gavidia, Cesar M.; Gilman, Robert Hugh; Angulo, Noelia P.; Brenner, Elliott C.; Lerner, Richard; Chomel, Bruno B. (Public Library of Science, 2013)
    Bartonella species are emerging infectious organisms transmitted by arthropods capable of causing long-lasting infection in mammalian hosts. Among over 30 species described from four continents to date, 15 are known to ...
  • Isolation and characterization of Acanthamoeba strains from soil samples in Gran Canaria, Canary Islands, Spain 
    Reyes-Batlle, María; Todd, Cheridah D.; Martín-Navarro, Carmen M.; López-Arencibia, Atteneri; Cabello Vílchez, Alfonso Martín; González, Ana C.; Córdoba-Lanús, Elizabeth; Lindo, John F.; Valladares, Basilio; Piñero, José E.; Lorenzo-Morales, Jacob (Springer Verlag, 2014)
    Free-living Amoebae of Acanthamoeba genus include non-pathogenic and pathogenic strains that are currently classified in 18 different genotypes, T1-T18. In this study, a survey was carried out to evaluate the presence of ...
  • The isolation of Balamuthia mandrillaris from environmental sources from Peru 
    Cabello Vílchez, Alfonso Martín; Reyes-Batlle, María; Montalbán-Sandoval, Esmelda; Martín-Navarro, Carmen Ma.; López-Arencibia, Atteneri; Elias-Letts, Rafaela; Guerra, Humberto; Gotuzzo Herencia, José Eduardo; Martínez-Carretero, Enrique; Piñero, José E.; Maciver, Sutherland K.; Valladares, Basilio; Lorenzo-Morales, Jacob (Springer Verlag, 2014)
    Balamuthia mandrillaris is an opportunistic free-living amoeba that has been reported to cause skin lesions and the fatal Balamuthia amoebic encephalitis (BAE) in humans and other animals. Currently, around 200 human BAE ...
  • Malaria vector species in amazonian Peru co-occur in larval habitats but have distinct larval microbial communities 
    Prussing, Catharine; Saavedra Romero, Marlon Pierino; Bickersmith, Sara A.; Alava, Freddy; Guzman Guzman, Mitchel Anthony; Manrique, Edgar; Carrasco Escobar, Gabriel; Moreno, Marta; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael; Conn, Jan E. (Public Library of Science, 2019)
    In Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source ...
  • Molecular characterization of the Taenia solium Tso31 antigen and homologous of other Taenia species from Peru 
    Vargas-Calla, Ana; Gomez-Puerta, Luis A.; Lopez, Maria T.; García Lescano, Héctor Hugo; Gonzalez Zariquiey, Armando Emiliano; Cysticercosis Working Group in Peru (Springer Verlag, 2019)
    Several studies have been performed to determine specific antigens for the diagnosis of tapeworms. One of these antigens is Tso31, which is used to differentiate Taenia solium and Taenia saginata in human feces. The aim ...
  • Molecular typing of "Candidatus bartonella ancashi," A new human pathogen causing Verruga Peruana 
    Mullins, Kristin E.; Hang, Jun; Jiang, Ju; Leguia, Mariana; Kasper, Matthew R.; Maguiña Vargas, Ciro; Jarman, Richard G.; Blazes, David L.; Richards, Allen L. (American Society for Microbiology, 2013)
    A recently described clinical isolate, “Candidatus Bartonella ancashi,” was obtained from a blood sample of a patient presenting with verruga peruana in the Ancash region of Peru. This sample and a second isolate obtained ...
  • A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon 
    Falconi-Agapito, Francesca; Selhorst, Philippe; Merino, Xiomara; Torres, Fiorella; Michiels, Johan; Fernandez, Connie; Talledo Albujar, Michael John; Ariën, Kevin K. (Elsevier, 2020)
    We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant ...
  • Pathogenomic Inference of Virulence-Associated Genes in Leptospira interrogans 
    Lehmann, Jason S.; Fouts, Derrick E.; Haft, Daniel H.; Cannella, Anthony P.; Ricaldi, Jessica N.; Brinkac, Lauren; Harkins, Derek; Durkin, Scott; Sanka, Ravi; Sutton, Granger; Moreno, Angelo; Vinetz, Joseph Michael; Matthias, Michael A. (Public Library of Science, 2013)
    Leptospirosis is a globally important, neglected zoonotic infection caused by spirochetes of the genus Leptospira. Since genetic transformation remains technically limited for pathogenic Leptospira, a systems biology ...
  • Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World 
    Yalcindag, Erhan; Rougeron, Virginie; Elguero, Eric; Arnathau, Céline; Durand, Patrick; Brisse, Sylvain; Diancourt, Laure; Aubouy, Agnes; Becquart, Pierre; D'Alessandro, Umberto; Fontenille, Didier; Gamboa Vilela, Dionicia Baziliza; Maestre, Amanda; Ménard, Didier; Musset, Lisie; Noya, Oscar; Veron, Vincent; Wide, Albina; Carme, Bernard; Legrand, Eric; Chevillon, Christine; Ayala, Francisco J.; Renaud, Francois; Prugnolle, Franck (Wiley, 2014)
    Pathogens, which have recently colonized a new host species or new populations of the same host, are interesting models for understanding how populations may evolve in response to novel environments. During its colonization ...
  • Simultaneous RNA quantification of human and retroviral genomes reveals intact interferon signaling in HTLV-1-infected CD4+ T cell lines 
    Moens, B.; Pannecouque, C.; Lápez, G.; Talledo Albujar, Michael John; Gotuzzo Herencia, José Eduardo; Khouri, R.; Bittencourt, A.; Farré, L.; Galvão-Castro, B.; Vandamme, A.-M.; Van Weyenbergh, J. (BioMed Central, 2012)
    Background: IFN- contributes extensively to host immune response upon viral infection through antiviral, pro-apoptotic, antiproliferative and immunomodulatory activities. Although extensively documented in various types ...
  • Transcription of TP0126, Treponema pallidum putative OmpW homolog, is regulated by the length of a homopolymeric guanosine repeat 
    Giacani, L.; Brandt, S.L.; Ke, W.; Reid, T.B.; Molini, B.J.; Iverson-Cabral, S.; Ciccarese, G.; Drago, F.; Lukehart, S.A.; Centurion-Lara, A. (American Society for Microbiology, 2015)
    An effective mechanism for introduction of phenotypic diversity within a bacterial population exploits changes in the length of repetitive DNA elements located within gene promoters. This phenomenon, known as phase variation, ...
  • Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum 
    Haynes, Austin M.; Fernandez, Mark; Romeis, Emily; Mitjà, Oriol; Konda, Kelika A.; Vargas Rivera, Silver Keith; Eguiluz, Maria; Caceres Palacios, Carlos Fernando; Klausner, Jeffrey D.; Giacani, Lorenzo (Public Library of Science, 2021)
    BACKGROUND: An effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis. Although the combination ...

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