• Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South Africa 

  Soetedjo, Nanny N. M.; McAllister, Susan M.; Ugarte‐Gil, Cesar; Firanescu, Adela G.; Ronacher, Katharina; Alisjahbana, Bachti; Costache, Anca L.; Zubiate, Carlos; Malherbe, Stephanus T.; Koesoemadinata, Raspati C.; Laurence, Yoko V.; Pearson, Fiona; Kerry‐Barnard, Sarah; Ruslami, Rovina; Moore, David A. J.; Ioana, Mihai; Kleynhans, Leanie; Permana, Hikmat; Hill, Philip C.; Mota, Maria; Walzl, Gerhard; Dockrell, Hazel M.; Critchley, Julia A.; Crevel, Reinout van (Wiley Online Library, 2018)

  Objective To describe the characteristics and management of Diabetes mellitus (DM) patients from low- and middle-income countries (LMIC). Methods We systematically characterised consecutive DM patients attending public ...
• Socioeconomic Factors Associated with Fasciola hepatica Infection Among Children from 26 Communities of the Cusco Region of Peru 

  Cabada, Miguel M.; Morales, Maria Luisa; Webb, Camille M.; Yang, Logan; Bravenec, Chelsey A.; Lopez, Martha; Bascope, Ruben; Jr, A. Clinton White; Gotuzzo, Eduardo (The American Society of Tropical Medicine and Hygiene, 2018)

  Fasciola hepatica is the most widely distributed trematode-affecting humans. The Andes Mountains are highly endemic for fascioliasis. We report results of a cross-sectional study evaluating the epidemiology of Fasciola ...
• Virulence Factor RNA Transcript Expression in Cultured Clinical Isolates of Leishmania Does Not Vary by Host Age 

  Mukkala, A.; Kariyawasam, R.; Lau, R.; Valencia, B.; Llanos-Cuentas, A.; Boggild, A.K. (Elsevier, 2018)

  Background: Virulence factors (VF) are endogenous molecules that often enhance the pathogenicity of an organism. The role of host age on the immunopathogenesis of leishmaniasis is poorly understood. Despite pediatric ...
• Prevalence and Association of Leishmania RNA Virus-1 (LRV-1) in Severe and Non-Severe Phenotypes of American Tegumentary Leishmaniasis from Peru 

  Kariyawasam, R.; Lau, R.; Valencia, B.; Llanos-Cuentas, A.; Boggild, A.K. (Elsevier, 2018)

  Background: American tegumentary leishmaniasis (ATL) comprises a discrete set of clinical presentations of leishmaniasis endemic to Latin America and particularly Peru. Leishmania RNA virus-1 (LRV-1) is a double stranded ...
• Influence of Leishmania RNA Virus-1 (LRV-1) on Virulence Factor RNA Transcript Expression of Leishmania Viannia spp 

  Kariyawasam, R.; Mukkala, A.; Lau, R.; Valencia, B.; Llanos-Cuentas, A.; Boggild, A.K. (Elsevier, 2018)

  Background: Leishmania RNA Virus-1 (LRV-1) is a double stranded RNA virus identified in strains of the Viannia subgenus in Latin America. Virulence factors (VFs) are gene products that augment pathogenicity of an organism, ...
• Spectrum of Bacterial Pathogens in Inflammatory and Non-Inflammatory Ulcers of American Cutaneous Leishmaniasis 

  Kariyawasam, R.; Gascon, B.; Mah, J.; Lau, R.; Valencia, B.; Llanos-Cuentas, A.; Boggild, A.K. (Elsevier, 2018)

  Background : Cutaneous leishmaniasis (CL) may present with an inflammatory phenotype, characterized by pain, erythema, and purulent exudate, which is typically treated with antibiotics prior to anti-Leishmania treatment. ...
• 1446 Tuberculosis as an occupational disease: knowledge, attitudes and practices among healthcare workers of a public hospital in lima-peru 

  Albino, Sandra; Bazo-Alvarez, Juan Carlos; Bosio, Davide; Gamarra, Maria; Samalvides, Frine (BMJ Publishing Group, 2018)

  Abstract Introduction Peru is one of the countries with the highest number of tuberculosis (TB) cases in the Americas with an incidence of 119 × 100 000 people in the last year. The Stop Tuberculosis Partnership recommends ...
• Antimicrobial susceptibility in blood and urine samples at a third level national hospital in Lima-Peru 2011-2014 

  Chincha, O.; Yeh, M.; Samalvides, F. (Elsevier, 2018)

  Background: The antimicrobial resistance map is a tool that allows to know the characteristics of microorganisms, its realization is necessary because the microorganisms are in constant change as a result of the exposure ...
• Neurocysticercosis in Pregnancy 

  Webb, Camille; Rosa, Mauricio La; Olson, Gayle; Cabada, Miguel (Thieme Open, 2018)

  The normal physiologic changes during pregnancy contribute to nutritional, metabolic, and immunologic adjustments, which can have an impact on the presentation of several diseases. New onset seizures during pregnancy and ...
• IFN-γ Response Is Associated to Time Exposure Among Asymptomatic Immune Responders That Visited American Tegumentary Leishmaniasis Endemic Areas in Peru 

  Best, Ivan; Privat-Maldonado, Angela; Cruz, María; Zimic, Mirko; Bras-Gonçalves, Rachel; Lemesre, Jean-Loup; Arévalo, Jorge (Frontiers Media, 2018)

  Clinical manifestations of American Tegumentary Leishmaniasis (ATL) include cutaneous (CL) and mucous forms (ML); however, there are asymptomatic individuals who despite being infected do not present any clinical manifestations. ...
• Point-of-Care Molecular Diagnosis of Cutaneous Leishmaniasis and Intercurrent Fungal and Mycobacterial Infections 

  Valencia, B.; Lau, R.; Kariyawasam, R.; Shao, E.; Llanos-Cuentas, A.; Boggild, A.K. (Elsevier, 2018)

  Background: Due to the highly toxic nature of standard drugs used in the treatment of cutaneous leishmaniasis (CL), and overlapping clinical features of CL with ulcers due to fungal and mycobacterial infections, confirmatory ...
• Early Retention in Care Neither Mediates Nor Modifies the Effect of Sex and Sexual Mode of HIV Acquisition on HIV Survival in the Americas 

  Coelho, Lara; Rebeiro, Peter F.; Castilho, Jessica L.; Caro-Vega, Yanink; Mejia, Fernando A.; Cesar, Carina; Cortes, Claudia P.; Padgett, Denis; McGowan, Catherine C.; Veloso, Valdiléa G.; Sterling, Timothy R.; Grinsztejn, Beatriz; Shepherd, Bryan E.; Luz, Paula M. (Mary Ann Liebert, 2018)

  Early retention in care, sex, and sexual mode of HIV acquisition has been associated with mortality risk among persons living with HIV (PLWH). We assessed whether early retention in care mediates or modifies the association ...
• Yellow fever vaccine and risk of developing serious adverse events: a systematic review 

  Porudominsky, Ruben; Gotuzzo, Eduardo H. (Pan American Health Organization, 2018)

  Objective. To evaluate contraindications and precautions for the yellow fever vaccine (YFV) in risk populations. Methods. A literature review was conducted by searching PubMed for “yellow fever vaccine” and “adverse events” ...
• The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia 

  Miller, William R.; Seas, Carlos; Carvajal, Lina P.; Diaz, Lorena; Echeverri, Aura M.; Ferro, Carolina; Rios, Rafael; Porras, Paola; Luna, Carlos; Gotuzzo, Eduardo; Munita, Jose M.; Nannini, Esteban; Carcamo, Cesar; Reyes, Jinnethe; Arias, Cesar A. (Oxford University Press, 2018)

  Background: Recent studies have favored the use of cefazolin over nafcillin for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. The clinical influence of the cefazolin inoculum effect ...
• Epidemiology, clinical features, and outcome of HTLV-1–related ATLL in an area of prevalence in the United States 

  Malpica, Luis; Pimentel, Agustin; Reis, Isildinha M.; Gotuzzo, Eduardo; Lekakis, Lazaros; Komanduri, Krishna; Harrington, Thomas; Barber, Glen N.; Ramos, Juan C. (The American Society of Hematology, 2018)

  Adult T-cell leukemia/lymphoma (ATLL) is a fatal disease caused by human T-cell leukemia virus type 1 (HTLV-1). We retrospectively analyzed 195 patients with ATLL (lymphomatous n = 96, acute n = 80, unfavorable chronic n ...
• Fulminant streptococcal toxic shock syndrome 

  Zavala, S.; Arias, M.; Legua, P. (Royal College of Physicians of Edinburgh, 2018)

  We present a case of a previously healthy 37-year-old male who developed fever, nausea, vomiting, diarrhoea, and hypovolaemia. Within 5.5 h he presented with tachycardia, tachypnoea, became hypotensive and displayed a ...
• Intestinal Myiasis Caused by Sarcophaga spp. in Cusco, Peru: A Case Report and Review of the Literature 

  Ly, Priscilla; Aizenberg, Adiel; Martin, Taylor; Lopez, Martha; Arturo Saldaña, Miguel; Hughes, Grant Leslie; Cabada, Miguel Mauricio (Hindawi Publishing Corporation, 2018)

  Myiasis is the infestation by dipterous fly larvae in humans and animals. The larvae can infect living or necrotic tissue involving the skin, nasopharynx, genitourinary, and gastrointestinal tracts. The accidental ingestion ...
• Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation 

  Olliaro, Piero; Grogl, Max; Boni, Marina; Carvalho, Edgar M.; Chebli, Houda; Cisse, Mamoudou; Diro, Ermias; Cota, Gláucia Fernandes; Erber, Astrid C.; Gadisa, Endalamaw; Handjani, Farhad; Khamesipour, Ali; Llanos-Cuentas, Alejandro; Carvajal, Liliana López; Grout, Lise; Lmimouni, Badre Eddine; Mokni, Mourad; Nahzat, Mohammad Sami; Salah, Afif Ben; Ozbel, Yusuf; Pascale, Juan Miguel; Molina, Nidia Rizzo; Rode, Joelle; Romero, Gustavo; Ruiz-Postigo, José Antonio; Saravia, Nancy Gore; Soto, Jaime; Uzun, Soner; Mashayekhi, Vahid; Vélez, Ivan Dario; Vogt, Florian; Zerpa, Olga; Arana, Byron (Public Library of Science, 2018)

  Introduction Progress with the treatment of cutaneous leishmaniasis (CL) has been hampered by inconsistent methodologies used to assess treatment effects. A sizable number of trials conducted over the years has generated ...
• Virologic failure and mortality in older ART initiators in a multisite Latin American and Caribbean Cohort 

  Carriquiry, Gabriela; Giganti, Mark J.; Castilho, Jessica L.; Jayathilake, Karu; Cahn, Pedro; Grinsztejn, Beatriz; Cortes, Claudia; Pape, Jean W.; Padgett, Denis; Sierra‐Madero, Juan; McGowan, Catherine C.; Shepherd, Bryan E.; Gotuzzo, Eduardo (BioMed Central, 2018)

  Introduction The “greying” of the HIV epidemic necessitates a better understanding of the healthcare needs of older HIV-positive adults. As these individuals age, it is unclear whether comorbidities and their associated ...
• Occurrence and molecular characterization of Giardia duodenalis cysts and Cryptosporidium oocysts in raw water samples from the Rímac River, Peru 

  Bautista, Meylin; Bonatti, Taís Rondello; Fiuza, Vagner Ricardo da S.; Terashima, Angelica; Canales-Ramos, Marco; José, Juliana; Franco, Regina Maura Bueno (Springer Verlag, 2018)

  Giardia and Cryptosporidium are potentially pathogenic protozoa which are ubiquitous in ambient surface water. The present study included 60 samples of surface water from three sampling sites from the Rímac River, Lima and ...

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