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  • Yellow fever vaccine and risk of developing serious adverse events: a systematic review 
    Porudominsky, Ruben; Gotuzzo, Eduardo H. (Pan American Health Organization, 2018)
    Objective. To evaluate contraindications and precautions for the yellow fever vaccine (YFV) in risk populations. Methods. A literature review was conducted by searching PubMed for “yellow fever vaccine” and “adverse events” ...
  • The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia 
    Miller, William R.; Seas, Carlos; Carvajal, Lina P.; Diaz, Lorena; Echeverri, Aura M.; Ferro, Carolina; Rios, Rafael; Porras, Paola; Luna, Carlos; Gotuzzo, Eduardo; Munita, Jose M.; Nannini, Esteban; Carcamo, Cesar; Reyes, Jinnethe; Arias, Cesar A. (Oxford University Press, 2018)
    Background: Recent studies have favored the use of cefazolin over nafcillin for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. The clinical influence of the cefazolin inoculum effect ...
  • Epidemiology, clinical features, and outcome of HTLV-1–related ATLL in an area of prevalence in the United States 
    Malpica, Luis; Pimentel, Agustin; Reis, Isildinha M.; Gotuzzo, Eduardo; Lekakis, Lazaros; Komanduri, Krishna; Harrington, Thomas; Barber, Glen N.; Ramos, Juan C. (The American Society of Hematology, 2018)
    Adult T-cell leukemia/lymphoma (ATLL) is a fatal disease caused by human T-cell leukemia virus type 1 (HTLV-1). We retrospectively analyzed 195 patients with ATLL (lymphomatous n = 96, acute n = 80, unfavorable chronic n ...
  • Fulminant streptococcal toxic shock syndrome 
    Zavala, S.; Arias, M.; Legua, P. (Royal College of Physicians of Edinburgh, 2018)
    We present a case of a previously healthy 37-year-old male who developed fever, nausea, vomiting, diarrhoea, and hypovolaemia. Within 5.5 h he presented with tachycardia, tachypnoea, became hypotensive and displayed a ...
  • Intestinal Myiasis Caused by Sarcophaga spp. in Cusco, Peru: A Case Report and Review of the Literature 
    Ly, Priscilla; Aizenberg, Adiel; Martin, Taylor; Lopez, Martha; Arturo Saldaña, Miguel; Hughes, Grant Leslie; Cabada, Miguel Mauricio (Hindawi Publishing Corporation, 2018)
    Myiasis is the infestation by dipterous fly larvae in humans and animals. The larvae can infect living or necrotic tissue involving the skin, nasopharynx, genitourinary, and gastrointestinal tracts. The accidental ingestion ...
  • Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation 
    Olliaro, Piero; Grogl, Max; Boni, Marina; Carvalho, Edgar M.; Chebli, Houda; Cisse, Mamoudou; Diro, Ermias; Cota, Gláucia Fernandes; Erber, Astrid C.; Gadisa, Endalamaw; Handjani, Farhad; Khamesipour, Ali; Llanos-Cuentas, Alejandro; Carvajal, Liliana López; Grout, Lise; Lmimouni, Badre Eddine; Mokni, Mourad; Nahzat, Mohammad Sami; Salah, Afif Ben; Ozbel, Yusuf; Pascale, Juan Miguel; Molina, Nidia Rizzo; Rode, Joelle; Romero, Gustavo; Ruiz-Postigo, José Antonio; Saravia, Nancy Gore; Soto, Jaime; Uzun, Soner; Mashayekhi, Vahid; Vélez, Ivan Dario; Vogt, Florian; Zerpa, Olga; Arana, Byron (Public Library of Science, 2018)
    Introduction Progress with the treatment of cutaneous leishmaniasis (CL) has been hampered by inconsistent methodologies used to assess treatment effects. A sizable number of trials conducted over the years has generated ...
  • Virologic failure and mortality in older ART initiators in a multisite Latin American and Caribbean Cohort 
    Carriquiry, Gabriela; Giganti, Mark J.; Castilho, Jessica L.; Jayathilake, Karu; Cahn, Pedro; Grinsztejn, Beatriz; Cortes, Claudia; Pape, Jean W.; Padgett, Denis; Sierra‐Madero, Juan; McGowan, Catherine C.; Shepherd, Bryan E.; Gotuzzo, Eduardo (BioMed Central, 2018)
    Introduction The “greying” of the HIV epidemic necessitates a better understanding of the healthcare needs of older HIV-positive adults. As these individuals age, it is unclear whether comorbidities and their associated ...
  • Occurrence and molecular characterization of Giardia duodenalis cysts and Cryptosporidium oocysts in raw water samples from the Rímac River, Peru 
    Bautista, Meylin; Bonatti, Taís Rondello; Fiuza, Vagner Ricardo da S.; Terashima, Angelica; Canales-Ramos, Marco; José, Juliana; Franco, Regina Maura Bueno (Springer Verlag, 2018)
    Giardia and Cryptosporidium are potentially pathogenic protozoa which are ubiquitous in ambient surface water. The present study included 60 samples of surface water from three sampling sites from the Rímac River, Lima and ...
  • Gnathostomiasis: an emerging infectious disease relevant to all dermatologists 
    Bravo, Francisco; Gontijo, Bernardo; Bravo, Francisco; Gontijo, Bernardo (SciELO, 2018)
    Gnathostomiasis is a parasitic infection caused by the third larval stage of nematodes of the genus Gnathostoma. The disease is endemic in some countries around the world. In the American continent, the majority of cases ...
  • Draft Genome Sequence of the First New Delhi Metallo-β-Lactamase (NDM-1)-Producing Escherichia coli Strain Isolated in Peru 
    Tamariz, Jesus; Llanos, Carlos; Seas, Carlos; Montenegro, Paola; Lagos, Jose; Fernandes, Miriam R.; Cerdeira, Louise; Lincopan, Nilton (American Society for Microbiology, 2018)
    We present here the draft genome sequence of the first New Delhi metallo-β-lactamase (NDM-1)-producing Escherichia coli strain, belonging to sequence type 155 (ST155), isolated in Peru. Assembly of this draft genome resulted ...
  • Durability of Efavirenz Compared With Boosted Protease Inhibitor-Based Regimens in Antiretroviral-Naïve Patients in the Caribbean and Central and South America 
    Caro-Vega, Yanink; Belaunzarán-Zamudio, Pablo F.; Crabtree-Ramírez, Brenda E.; Shepherd, Bryan E.; Grinsztejn, Beatriz; Wolff, Marcelo; Pape, Jean W.; Padgett, Denis; Gotuzzo, Eduardo; McGowan, Catherine C.; Sierra-Madero, Juan G. (Oxford University Press, 2018)
    Background Efavirenz (EFV) and boosted protease inhibitors (bPIs) are still the preferred options for firstline antiretroviral regimens (firstline ART) in Latin America and have comparable short-term efficacy. We assessed ...
  • Is substance use associated with HIV cascade outcomes in Latin America? 
    Boni, Raquel B. De; Peratikos, Meridith B.; Shepherd, Bryan E.; Grinsztejn, Beatriz; Cortés, Claudia; Padgett, Denis; Gotuzzo, Eduardo; Belaunzarán-Zamudio, Pablo F.; Rebeiro, Peter F.; Duda, Stephany N.; McGowan, Catherine C. (Public Library of Science, 2018)
    Background The HIV care cascade has improved in Latin America over the last decade. However, the influence of alcohol and noninjected drug use (NIDU) on cascade outcomes is mostly unknown. This study estimated the association ...
  • Patient-nominated supporters as facilitators for engagement in HIV care in a referral hospital in Peru: A retrospective cohort study 
    Prochazka, Mateo; Otero, Larissa; Konda, Kelika A.; González-Lagos, Elsa; Echevarría, Juan; Gotuzzo, Eduardo (Public Library of Science, 2018)
    Patient-nominated supporters can potentially improve the continuum of HIV care. We retrospectively determined factors associated with having a patient-nominated supporter among people living with HIV (PLWH), and its ...
  • HIV screening among newly diagnosed TB patients: a cross sectional study in Lima, Peru 
    Ramírez, Suzanne; Mejía, Fernando; Rojas, Marlene; Seas, Carlos; Van der Stuyft, Patrick; Gotuzzo, Eduardo; Otero, Larissa (BioMed Central, 2018)
    Background Since 2006, the Peruvian National TB program (NTP) recommends voluntary counseling and testing (VCT) for all tuberculosis (TB) patients. Responding to the differential burden of both diseases in Peru, TB is ...
  • Evaluating the care cascade after antiretroviral therapy initiation in Latin America 
    Wolff, M. J.; Cortes, C. P.; Mejía, F. A.; Padgett, D.; Belaunzarán-Zamudio, P.; Grinsztejn, B.; Giganti, M. J.; McGowan, C. C.; Rebeiro, P. F. (SAGE and Open Access, 2017)
    Accelerating antiretroviral therapy (ART) administration, improving retention, and achieving viral suppression in low- and middle-income countries must be prioritized. We evaluated trends and disparities in these milestones ...
  • Tegumentary leishmaniasis and coinfections other than HIV 
    Martinez, D. Y.; Verdonck, K.; Kaye, P. M.; Adaui, V.; Polman, K.; Llanos-Cuentas, A.; Dujardin, J.; Boelaert, M. (Public Library of Science, 2018)
    Infectious diseases are often studied one by one, but people can have more than one infection at the same time. This is likely to happen when different microorganisms are linked to specific geographical regions or living ...
  • Staphylococcus aureus bloodstream infections in Latin America: results of a multinational prospective cohort study 
    Seas, C.; Garcia, C.; Salles, M. J.; Labarca, J.; Luna, C.; Alvarez-Moreno, C.; Mejía-Villatoro, C.; Zurita, J.; Guzmán-Blanco, M.; Rodríguez-Noriega, E.; Reyes, J.; Arias, C. A.; Carcamo, C.; Gotuzzo, E. (Oxford University Press, 2018)
    "Substantial heterogeneity in the epidemiology and management of Staphylococcus aureus bacteraemia (SAB) occurs in Latin America. We conducted a prospective cohort study in 24 hospitals from nine Latin American countries. ...
  • Decreasing proportion of Anopheles darlingi biting outdoors between long-lasting insecticidal net distributions in peri-Iquitos, Amazonian Peru 
    Prussing, C.; Moreno, M.; Saavedra, M. P.; Bickersmith, S. A.; Gamboa, D.; Alava, F.; Schlichting, C. D.; Emerson, K. J.; Vinetz, J. M.; Conn, J. E. (BioMed Central, 2018)
    In Loreto Department, Peru, a successful 2005–2010 malaria control programme (known as PAMAFRO) included massive distribution of long-lasting insecticidal nets (LLINs). Additional local distribution of LLINs occurred in ...