Universidad Peruana Cayetano Heredia

Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa

Mostrar el registro sencillo del ítem

dc.contributor.author Grint, Daniel
dc.contributor.author Alisjhabana, Bachti
dc.contributor.author Ugarte-Gil, Cesar
dc.contributor.author Riza, Anca-Leila
dc.contributor.author Walzl, Gerhard
dc.contributor.author Pearson, Fiona
dc.contributor.author Ruslami, Rovina
dc.contributor.author Moore, David A. J.
dc.contributor.author Ioana, Mihai
dc.contributor.author McAllister, Susan
dc.contributor.author Ronacher, Katharina
dc.contributor.author Koeseomadinata, Raspati C.
dc.contributor.author Kerry-Barnard, Sarah R.
dc.contributor.author Coronel, Jorge
dc.contributor.author Malherbe, Stephanus T.
dc.contributor.author Dockrell, Hazel M.
dc.contributor.author Hill, Philip C.
dc.contributor.author Van Crevel, Reinout
dc.contributor.author Critchley, Julia A.
dc.date.accessioned 2018-11-08T19:39:21Z
dc.date.available 2018-11-08T19:39:21Z
dc.date.issued 2018
dc.identifier.uri http://doi.org/10.2471/BLT.17.206227
dc.identifier.uri http://repositorio.upch.edu.pe/handle/upch/3940
dc.description.abstract Objective To evaluate the performance of diagnostic tools for diabetes mellitus, including laboratory methods and clinical risk scores, in newly-diagnosed pulmonary tuberculosis patients from four middle-income countries. Methods In a multicentre, prospective study, we recruited 2185 patients with pulmonary tuberculosis from sites in Indonesia, Peru, Romania and South Africa from January 2014 to September 2016. Using laboratory-measured glycated haemoglobin (HbA1c) as the gold standard, we measured the diagnostic accuracy of random plasma glucose, point-of-care HbA1c, fasting blood glucose, urine dipstick, published and newly derived diabetes mellitus risk scores and anthropometric measurements. We also analysed combinations of tests, including a two-step test using point-of-care HbA1cwhen initial random plasma glucose was ≥6.1 mmol/L. Findings The overall crude prevalence of diabetes mellitus among newly diagnosed tuberculosis patients was 283/2185 (13.0%; 95% confidence interval, CI: 11.6–14.4). The marker with the best diagnostic accuracy was point-of-care HbA1c (area under receiver operating characteristic curve: 0.81; 95% CI: 0.75–0.86). A risk score derived using age, point-of-care HbA1c and random plasma glucose had the best overall diagnostic accuracy (area under curve: 0.85; 95% CI: 0.81–0.90). There was substantial heterogeneity between sites for all markers, but the two-step combination test performed well in Indonesia and Peru. Conclusion Random plasma glucose followed by point-of-care HbA1c testing can accurately diagnose diabetes in tuberculosis patients, particularly those with substantial hyperglycaemia, while reducing the need for more expensive point-of-care HbA1c testing. Risk scores with or without biochemical data may be useful but require validation.
dc.language.iso eng
dc.publisher World Health Organization
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Tuberculosis
dc.subject Diabetes Mellitus
dc.subject Diabetes Mellitus--diagnóstico
dc.title Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa
dc.type info:eu-repo/semantics/article
dc.identifier.journal Bulletin of the World Health Organization


Ficheros en el ítem

Ficheros Tamaño Formato Ver

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/restrictedAccess Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess

Buscar en el Repositorio


Listar

Mi cuenta

Estadísticas