Universidad Peruana Cayetano Heredia

Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting

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dc.contributor.author Van der Heijden, Yuri F.
dc.contributor.author Abdullah, Fareed
dc.contributor.author Andrade, Bruno B.
dc.contributor.author Andrews, Jason R.
dc.contributor.author Christopher, Devasahayam J.
dc.contributor.author Croda, Julio
dc.contributor.author Ewing, Heather
dc.contributor.author Haas, David W.
dc.contributor.author Hatherill, Mark
dc.contributor.author Horsburgh, C. Robert
dc.contributor.author Mave, Vidya
dc.contributor.author Nakaya, Helder I.
dc.contributor.author Rolla, Valeria
dc.contributor.author Srinivasan, Sudha
dc.contributor.author Sugiyono, Retna Indah
dc.contributor.author Ugarte-Gil, Cesar
dc.contributor.author Hamilton, Carol
dc.date.accessioned 2018-11-08T19:39:22Z
dc.date.available 2018-11-08T19:39:22Z
dc.date.issued 2018
dc.identifier.uri http://doi.org/10.1016/j.tube.2018.09.009
dc.identifier.uri http://repositorio.upch.edu.pe/handle/upch/3941
dc.description.abstract RePORT International is a global network of research sites in India, Brazil, Indonesia, South Africa, China, and the Philippines dedicated to collaborative tuberculosis research in the context of HIV. A standardized research protocol (the Common Protocol) guides the enrollment of participants with active pulmonary tuberculosis and contacts into observational cohorts. The establishment of harmonized clinical data and bio-repositories will allow cutting-edge, large-scale advances in the understanding of tuberculosis, including identiï¬ cation of novel biomarkers for progression to active tuberculosis and relapse after treatment. The RePORT International infrastructure aims to support research capacity development through enabling globally-diverse collaborations. To that end, representatives from the RePORT International network sites, funding agencies, and other stakeholders gathered together in Brazil in September 2017 to present updates on relevant research ï¬ ndings and discuss ideas for collaboration. Presenters emphasized research involving biomarker identiï¬ cation for incipient tuberculosis, host immunity and pharmacogenomics, co-morbidities such as HIV and type 2 diabetes mellitus, and tuberculosis transmission in vulnerable and high-risk populations. Currently, 962 active TB participants and 670 household contacts have contributed blood, sputum, urine and microbes to in-country biorepositories. Crossconsortium collaborations have begun sharing data and specimens to analyze molecular and cytokine predictive patterns.
dc.language.iso eng
dc.publisher Elsevier
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Transmission
dc.subject Pharmacogenomics
dc.subject Incipient tuberculosis
dc.subject HIV
dc.subject Diabetes
dc.subject Biomarkers
dc.title Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting
dc.type info:eu-repo/semantics/article
dc.identifier.journal Tuberculosis


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