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Evaluation of the efficacy, safety and acceptability of a fish protein isolate in the nutrition of children under 36 months of age

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dc.contributor.author Ochoa, Theresa J.
dc.contributor.author Baiocchi, Nelly
dc.contributor.author Valdiviezo, Gladys
dc.contributor.author Bullon, Vanessa
dc.contributor.author Campos, Miguel
dc.contributor.author Llanos-Cuentas, Alejandro
dc.date.accessioned 2019-01-25T15:18:34Z
dc.date.available 2019-01-25T15:18:34Z
dc.date.issued 2017
dc.identifier.uri http://doi.org/10.1017/S136898001700163X
dc.identifier.uri http://repositorio.upch.edu.pe/handle/upch/4648
dc.description.abstract OBJECTIVE: To determine the effect of a fish protein isolate (FPi), administered over 6 months, on the growth of children aged 6-36 months, measured by Z-scores of height-for-age (HAZ) and weight-for-height (WHZ), compared with the standard meal without FPi; and to determine the safety and acceptability of FPi daily consumption. DESIGN: Cluster-randomized community-based controlled trial. For 6 months, the centres received either FPi replacing 50 % of total proteins in the diet or standard protein. HAZ and WHZ were used to determine the effect on growth. Acceptability was determined by daily consumption, measured by weighing the servings before and after consumption. SETTING: Day care centres and community nutritional centres in northern Lima, Peru. SUBJECTS: Children (n 441) aged 6-36 months. RESULTS: Four centres were randomized to the intervention with FPi, five centres were randomized to the standard control diet. More than 36 900 meals were prepared and administered in a supervised manner. Both groups received the same amounts of energy and proteins daily (proteins about 12-15 % of total energy). Growth of children who received the FPi diet was similar to that of children with the standard diet. Consumption was similar in the FPi and control groups (70 v. 80 % of amount offered, respectively). The protein was safe and well tolerated. No adverse events were reported. However, the cost of the intervention with FPi was 20-40 % lower v. the standard diet with animal protein derived from beef, chicken, eggs or liver. CONCLUSIONS: The FPi was well accepted and there was no significant difference in growth between both groups. FPi is a potential source of animal protein at lower cost.
dc.language.iso eng
dc.publisher Cambridge University Press
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Diet
dc.subject Dietary Supplements
dc.subject Body Height
dc.subject Body Weight
dc.subject Child Day Care Centers
dc.subject Child, Preschool
dc.subject Children
dc.subject Cluster Analysis
dc.subject Dietary protein
dc.subject Female
dc.subject Fish protein isolate
dc.subject Fish Proteins/administration & dosage
dc.subject Follow-Up Studies
dc.subject Food consumption
dc.subject Humans
dc.subject Infant
dc.subject Infant Nutritional Physiological Phenomena
dc.subject Male
dc.subject Malnutrition
dc.subject Nutritional Status
dc.subject Peru
dc.subject Single-Blind Method
dc.subject Treatment Outcome
dc.title Evaluation of the efficacy, safety and acceptability of a fish protein isolate in the nutrition of children under 36 months of age
dc.type info:eu-repo/semantics/article
dc.identifier.journal Public Health Nutrition


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