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Browsing by Author "Aldana, I."

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Aryl piperazine and pyrrolidine as antimalarial agents. Synthesis and investigation of structure-activity relationships

Mendoza, A.; Pérez-Silanes, S.; Quiliano, M.; Pabón, A.; Galiano, S.; González, G.; Garavito, G.; Zimic-Peralta, Mirko Juan; Vaisberg Wollach, Abraham Jaime; Aldana, I.; Monge, A.; Deharo, E. (Elsevier, 2011)

Piperazine and pyrrolidine derivatives were synthesised and evaluated for their capacity to inhibit the growth of Plasmodium falciparum chloroquine-resistant (FCR-3) strain in culture. The combined presence of a hydroxyl ...
New salicylamide and sulfonamide derivatives of quinoxaline 1,4-di-N-oxide with antileishmanial and antimalarial activities

Barea, C.; Pabón, A.; Castillo Pareja, Denis Helan; Zimic-Peralta, Mirko Juan; Quiliano, M.; Galiano, S.; Pérez-Silanes, S.; Monge, A.; Deharo, E.; Aldana, I. (Elsevier, 2011)

Continuing with our efforts to identify new active compounds against malaria and leishmaniasis, 14 new 3-amino-1,4-di-N-oxide quinoxaline-2- carbonitrile derivatives were synthesized and evaluated for their in vitro ...
Trypanocidal properties, structure-activity relationship and computational studies of quinoxaline 1,4-di-N-oxide derivatives

Estevez, Y.; Quiliano, M.; Burguete, A.; Cabanillas Amado, Billy Joel; Zimic-Peralta, Mirko Juan; Málaga, E.; Verastegui Pimentel, Manuela Renee; Pérez-Silanes, S.; Aldana, I.; Monge, A.; Castillo Pareja, Denis Helan; Deharo, E. (Elsevier, 2011)

Pyrazole and propenone quinoxaline derivatives were tested against intracellular forms of Leishmania peruviana and Trypanosoma cruzi. Both series were tested for toxicity against proliferative and non-proliferative cells. ...

Browsing by Author "Aldana, I."

Browsing by Author "Aldana, I."

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