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Browsing by Author "Alland, D."

Browsing by Author "Alland, D."

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  • Nahid, P.; Kim, P.S.; Evans, Carlton Anthony William; Alland, D.; Barer, M.; Diefenbach, J.; Ellner, J.; Hafner, R.; Hamilton, C.D.; Iademarco, M.F.; Ireton, G.; Kimerling, M.E.; Lienhardt, C.; MacKenzie, W.R.; Murray, M.; Perkins, M.D.; Posey, J.E.; Roberts, T.; Sizemore, C.; Stevens, W.S.; Via, L.; Williams, S.D.; Yew, W.W.; Swindells, S. (Oxford University Press, 2012)
    The development, evaluation, and implementation of new and improved diagnostics have been identified as critical needs by human immunodeficiency virus (HIV) and tuberculosis researchers and clinicians alike. These needs ...
  • Rowneki, M.; Aronson, N.; Du, P.; Sachs, P.; Blakemore, R.; Chakravorty, S.; Levy, S.; Jones, A.L.; Trivedi, G.; Chebore, S.; Addo, D.; Byarugaba, D.K.; Njobvu, P.D.; Wabwire-Mangen, F.; Erima, B.; Ramos, E.S.; Evans, Carlton Anthony William; Hale, B.; Mancuso, J.D.; Alland, D. (Public Library of Science, 2020)
    Background: Drug susceptibility testing for Mycobacterium tuberculosis (MTB) is difficult to perform in resource-limited settings where Acid Fast Bacilli (AFB) smears are commonly used for disease diagnosis and monitoring. ...
  • Boehme, C.C.; Nicol, M.P.; Nabeta, P.; Michael, J.S.; Gotuzzo Herencia, José Eduardo; Tahirli, R.; Gler, M.T.; Blakemore, R.; Worodria, W.; Gray, C.; Huang, L.; Cáceres Nakiche, Tatiana; Mehdiyev, R.; Raymond, L.; Whitelaw, A.; Sagadevan, K.; Alexander, H.; Albert, H.; Cobelens, F.; Cox, H.; Alland, D.; Perkins, M.D. (Elsevier, 2011)
    The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA) can detect tuberculosis and its multidrug-resistant form with very high sensitivity and specificity in controlled studies, but no performance data exist from district ...
  • Blakemore, R.; Nabeta, P.; Davidow, A.L.; Vadwai, V.; Tahirli, R.; Munsamy, V.; Nicol, M.; Jones, M.; Persing, D.H.; Hillemann, D.; Ruesch-Gerdes, S.; Leisegang, F.; Zamudio Fuertes, Carlos Eduardo; Rodrigues, C.; Boehme, C.C.; Perkins, M.D.; Alland, D. (American Thoracic Society, 2011)
    Rationale: The Xpert MTB/RIF is an automated molecular test for Mycobacterium tuberculosis that estimates bacterial burden by measuring the threshold-cycle (Ct) of its M. tuberculosis-specific real-time polymerase chain ...
  • Jayakumar, A.; Savic, R. M.; Everett, C. K.; Benator, D.; Alland, D.; Heilig, C. M.; Weiner, M.; Friedrich, S. O.; Martinson, N. A.; Kerrigan, A.; Zamudio Fuertes, Carlos Eduardo; Goldberg, S. V.; Whitworth, W. C.; Davis, J. L.; Nahid, P. (American Society for Microbiology, 2016)
    The Xpert MTB/RIF assay is both sensitive and specific as a diagnostic test. Xpert also reports quantitative output in cycle threshold (CT) values, which may provide a dynamic measure of sputum bacillary burden when used ...

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