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Browsing by Author "Magalhaes, Wagner C. S."

Browsing by Author "Magalhaes, Wagner C. S."

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  • Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes 
    Scliar, Marilia O.; Sant'Anna, Hanaisa P.; Santolalla Robles, Meddly Leslye; Leal, Thiago P.; Araujo, Nathalia M.; Alvim, Isabela; Borda, Victor; Magalhaes, Wagner C. S.; Gouveia, Mateus H.; Lyra, Ricardo; Machado, Moara; Michelin, Lucas; Rodrigues, Maira R.; Araujo, Gilderlanio S.; Kehdy, Fernanda S. G.; Zolini, Camila; Peixoto, Sergio V.; Luizon, Marcelo R.; Lobo, Francisco; Naslavsky, Michel S.; Yamamoto, Guilherme L.; Duarte, Yeda A. O.; Hansen, Matthew E. B.; Norris, Shane A.; Gilman, Robert Hugh; Guio, Heinner; Hsing, Ann W.; Mbulaiteye, Sam M.; Mensah, James; Dutil, Julie; Yeager, Meredith; Yeboah, Edward; Tishkoff, Sarah A.; Choudhury, Ananyo; Ramsay, Michele; Passos-Bueno, Maria Rita; Zatz, Mayana; O'Connor, Timothy D.; Pereira, Alexandre C.; Barreto, Mauricio L.; Lima-Costa, Maria Fernanda; Horta, Bernardo L.; Tarazona-Santos, Eduardo (Springer, 2021)
    Background/objectives: Admixed populations are a resource to study the global genetic architecture of complex phenotypes, which is critical, considering that non-European populations are severely underrepresented in genomic ...
  • Origins, admixture dynamics and homogenization of the African gene pool in the Americas 
    Gouveia, Mateus H.; Borda, Victor; Leal, Thiago P.; Moreira, Rennan G.; Bergen, Andrew W.; Kehdy, Fernanda S. G.; Alvim, Isabela; Aquino, Marla M.; Araujo, Gilderlanio S.; Araujo, Nathalia M.; Furlan, Vinicius; Liboredo, Raquel; Machado, Moara; Magalhaes, Wagner C. S.; Michelin, Lucas A.; Rodrigues, Maíra R.; Rodrigues-Soares, Fernanda; Sant Anna, Hanaisa P.; Santolalla Robles, Meddly Leslye; Scliar, Marília O.; Soares-Souza, Giordano; Zamudio, Roxana; Zolini, Camila; Bortolini, Maria Catira; Dean, Michael; Gilman, Robert Hugh; Guio, Heinner; Rocha, Jorge; Pereira, Alexandre C.; Barreto, Mauricio L.; Horta, Bernardo L.; Lima-Costa, Maria F.; Mbulaiteye, Sam M.; Chanock, Stephen J.; Tishkoff, Sarah A.; Yeager, Meredith; Tarazona-Santos, Eduardo (Oxford University Press, 2020)
    The Transatlantic Slave Trade transported more than 9 million Africans to the Americas between the early 16th and the mid-19th centuries. We performed a genome-wide analysis using 6,267 individuals from 25 populations to ...
  • Population genetics of PDE4B (Phosphodiesterase-4B) in neglected native americans: implications for cancer pharmacogenetics. 
    Moreira, Rennan Garcias; Saraiva-Duarte, Julia Maria; Pereira, Alexandre Costa; Sosa-Macias, Martha; Galaviz-Hernandez, Carlos; Santolalla Robles, Meddly Leslye; Magalhaes, Wagner C. S.; Zolini, Camila; Leal, Thiago Peixoto; Balazs, Zsolt; Llerena, Adrian; Gilman, Robert Hugh; Mill, Jose Geraldo; Borda, Victor; Guio, Heinner; O'Connor, Timothy D.; Tarazona-Santos, Eduardo; Rodrigues-Soares, Fernanda (Wiley, 2022)
    PDE4B (phosphodiesterase-4B) has an important role in cancer and in pharmacology of some disorders, such as inflammatory diseases. Remarkably in Native Americans, PDE4B variants are associated with acute lymphoblastic ...

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