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Browsing by Author "Xavier, Denis"

Browsing by Author "Xavier, Denis"

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  • Antithrombotic Therapy in Patients with Atrial Fibrillation and Acute Coronary Syndrome Treated Medically or with Percutaneous Coronary Intervention or Undergoing Elective Percutaneous Coronary Intervention: Insights from the AUGUSTUS Trial. 
    Windecker, Stephan; Lopes, Renato D.; Massaro, Tyler; Jones-Burton, Charlotte; Granger, Christopher B.; Aronson, Ronald; Heizer, Gretchen; Goodman, Shaun G.; Darius, Harald; Jones, W. Schuyler; Aschermann, Michael; Brieger, David; Cura, Fernando; Engstrom, Thomas; Fridrich, Viliam; Halvorsen, Sigrun; Huber, Kurt; Kang, Hyun-Jae; Leiva-Pons, Jose L.; Lewis, Basil S.; Málaga Rodríguez, Germán Javier; Meneveau, Nicolas; Merkely, Bela; Milicic, Davor; Morais, Joao; Potpara, Tatjana S.; Raev, Dimitar; Sabate, Manel; de Waha-Thiele, Suzanne; Welsh, Robert C.; Xavier, Denis; Mehran, Roxana; Alexander, John H. (Wolters Kluwer Health, 2019)
    Background: The safety and efficacy of antithrombotic regimens may differ between patients with atrial fibrillation (AF) who have acute coronary syndromes (ACS), treated medically or with percutaneous coronary intervention ...
  • Aspirin in patients with previous percutaneous coronary intervention undergoing noncardiac surgery 
    Graham, Michelle M.; Sessler, Daniel I.; Parlow, Joel L.; Biccard, Bruce M.; Guyatt, Gordon; Leslie, Kate; Chan, Matthew T. V.; Meyhoff, Christian S.; Xavier, Denis; Sigamani, Alben; Kumar, Priya A.; Mrkobrada, Marko; Cook, Deborah J.; Tandon, Vikas; Alvarez-Garcia, Jesus; Villar, Juan Carlos; Painter, Thomas W.; Landoni, Giovanni; Fleischmann, Edith; Lamy, Andre; Whitlock, Richard; Le Manach, Yannick; Aphang-Lam, Meylin; Cata, Juan P.; Gao, Peggy; Terblanche, Nicolaas C. S.; Ramana, Pamidimukkala V.; Jamieson, Kim A.; Bessissow, Amal; Mendoza, Gabriela R.; Ramirez, Silvia; Diemunsch, Pierre A.; Yusuf, Salim; Devereaux, P. J. (American College of Physicians, 2018)
    Background: Uncertainty remains about the effects of aspirin in patients with prior percutaneous coronary intervention (PCI) having noncardiac surgery. Objective: To evaluate benefits and harms of perioperative aspirin in ...
  • Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery 
    Devereaux, P. J.; Biccard, Bruce M.; Sigamani, Alben; Xavier, Denis; Chan, Matthew T. V.; Srinathan, Sadeesh K.; Walsh, Michael; Abraham, Valsa; Pearse, Rupert; Wang, C. Y.; Sessler, Daniel I.; Kurz, Andrea; Szczeklik, Wojciech; Berwanger, Otavio; Villar, Juan Carlos; Málaga Rodríguez, Germán Javier; Garg, Amit X.; Chow, Clara K.; Ackland, Gareth; Patel, Ameen; Borges, Flavia Kessler; Belley-Cote, Emilie P.; Duceppe, Emmanuelle; Spence, Jessica; Tandon, Vikas; Williams, Colin; Sapsford, Robert J.; Polanczyk, Carisi A.; Tiboni, Maria; Alonso-Coello, Pablo; Faruqui, Atiya; Heels-Ansdell, Diane; Lamy, Andre; Whitlock, Richard; LeManach, Yannick; Roshanov, Pavel S.; McGillion, Michael; Kavsak, Peter; McQueen, Matthew J.; Thabane, Lehana; Rodseth, Reitze N.; Buse, Giovanna A. Lurati; Bhandari, Mohit; Garutti, Ignacia; Jacka, Michael J.; Schunemann, Holger J.; Cortes, Olga Lucia; Coriat, Pierre; Dvirnik, Nazari; Botto, Fernando; Pettit, Shirley; Jaffe, Allan S.; Guyatt, Gordon H. (American Medical Association, 2017)
    Importance: Little is known about the relationship between perioperative high-sensitivity troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac surgery (MINS). Objective: To determine ...
  • Association of Psychosocial Stress with Risk of Acute Stroke 
    Reddin, Catriona; Murphy, Robert; Hankey, Graeme J.; Judge, Conor; Xavier, Denis; Rosengren, Annika; Ferguson, John; Alvarez-Iglesias, Alberto; Oveisgharan, Shahram; Iversen, Helle K.; Lanas, Fernando; Al-Hussein, Fawaz; Czlonkowska, Anna; Oguz, Aytekin; McDermott, Clodagh; Pogosova, Nana; Málaga Rodríguez, Germán Javier; Langhorne, Peter; Wang, Xingyu; Wasay, Mohammad; Yusuf, Salim; O'Donnell, Martin; INTERSTROKE investigators (American Medical Association, 2022)
    Importance: Psychosocial stress is considered a modifiable risk factor for stroke. Given the prevalence of chronic and acute exposure to stress, it represents a potentially attractive target for population-health interventions. ...
  • Comparison of Nonblood-Based and Blood-Based Total CV Risk Scores in Global Populations 
    Gaziano, Thomas-A.; Abrahams-Gessel, Shafika; Alam, Sartaj; Alam, Dewan; Ali, Mohammed; Bloomfield, Gerald; Carrillo Larco, Rodrigo Martín; Dorairaj, Prabhakaran; Gutierrez, Laura; Irazola, Vilma; Levitt, Naomi-S.; Miranda, J. Jaime; Bernabé Ortiz, Antonio; Pandya, Ankur; Rubinstein, Adolfo; Steyn, Krisela; Xavier, Denis; Yan, Lijing-L. (Elsevier, 2016)
    BACKGROUND: Cost-effective primary prevention of cardiovascular disease (CVD) in low- and middle-income countries requires accurate risk assessment. Laboratory-based risk tools currently used in high-income countries are ...
  • Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study 
    O'Donnell, Martin-J.; Chin, Siu-Lim; Rangarajan, Sumathy; Xavier, Denis; Liu, Lisheng; Zhang, Hongye; Rao-Melacini, Purnima; Zhang, Xiaohe; Pais, Prem; Agapay, Steven; Lopez-Jaramillo, Patricio; Damasceno, Albertino; Langhorne, Peter; McQueen, Matthew-J.; Rosengren, Annika; Dehghan, Mahshid; Hankey, Graeme-J.; Dans, Antonio-L.; Elsayed, Ahmed; Avezum, Alvaro; Mondo, Charles; Diener, Hans-Christoph; Ryglewicz, Danuta; Czlonkowska, Anna; Pogosova, Nana; Weimar, Christian; Iqbal, Romaina; Diaz, Rafael; Yusoff, Khalid; Yusufali, Afzalhussein; Oguz, Aytekin; Wang, Xingyu; Penaherrera, Ernesto; Lanas, Fernando; Ogah, Okechukwu-S.; Ogunniyi, Adesola; Iversen, Helle-K.; Málaga Rodríguez, Germán Javier; Rumboldt, Zvonko; Oveisgharan, Shahram; Al-Hussain, Fawaz; Magazi, Daliwonga; Nilanont, Yongchai; Ferguson, John; Pare, Guillaume; Yusuf, Salim (Elsevier, 2016)
    BACKGROUND: Stroke is a leading cause of death and disability, especially in low-income and middle-income countries. We sought to quantify the importance of potentially modifiable risk factors for stroke in different regions ...
  • Hypertension Prevalence, Awareness, Treatment, and Control in Selected LMIC Communities: Results From the NHLBI/UHG Network of Centers of Excellence for Chronic Diseases 
    Irazola, Vilma-E.; Gutierrez, Laura; Bloomfield, Gerald; Carrillo Larco, Rodrigo Martín; Dorairaj, Prabhakaran; Gaziano, Thomas; Levitt, Naomi-S.; Miranda, J. Jaime; Bernabé Ortiz, Antonio; Steyn, Krisela; Wu, Yangfeng; Xavier, Denis; Yan, Lijing-L.; He, Jiang; Rubinstein, Adolfo (Elsevier, 2016)
    BACKGROUND: Hypertension is the leading cause of cardiovascular disease and premature death worldwide. The prevalence of this public health problem is increasing in low- and middle-income countries (LMICs) in both urban ...
  • Management of NCD in low- And middle-income countries 
    Checkley, William; Ghannem, Hassen; Irazola, Vilma; Kimaiyo, Sylvester; Levitt, Naomi S.; Miranda, J. Jaime; Niessen, Louis; Prabhakaran, Dorairaj; Rabadán-Diehl, Cristina; Ramirez-Zea, Manuel; Rubinstein, Adolfo; Sigamani, Alben; Smith, Richard; Tandon, Nikhil; Wu, Yangfeng; Xavier, Denis; Yan, Lijing L. (Elsevier, 2014)
    Noncommunicable disease (NCD), comprising cardiovascular disease, stroke, diabetes, and chronic obstructive pulmonary disease, are increasing in incidence rapidly in low- and middle-income countries (LMICs). Some patients ...
  • One-year outcomes after discharge from noncardiac surgery and association between pre-discharge complications and death after discharge: analysis of the VISION prospective cohort study. 
    Roshanov, Pavel S.; Chan, Matthew T. V.; Borges, Flavia K.; Conen, David; Wang, C. Y.; Xavier, Denis; Berwanger, Otavio; Marcucci, Maura; Sessler, Daniel I.; Szczeklik, Wojciech; Spence, Jessica; Alonso-Coello, Pablo; Fernández, Carmen; Pearse, Rupert M.; Málaga Rodríguez, Germán Javier; Garg, Amit X.; Srinathan, Sadeesh K.; Jacka, Michael J.; Tandon, Vikas; McGillion, Michael; Popova, Ekaterine; Sigamani, Alben; Abraham, Valsa; Biccard, Bruce M.; Villar, Juan Carlos; Chow, Clara K.; Polanczyk, Carísi A.; Tiboni, Maria; Whitlock, Richard; Ackland, Gareth L.; Panju, Mohamed; Lamy, André; Sapsford, Robert; Williams, Colin; Wu, William Ka Kei; Cortés, Olga L.; MacNeil, S. Danielle; Patel, Ameen; Belley-Côté, Emilie P.; Ofori, Sandra; McIntyre, William F.; Leong, Darryl P.; Heels-Ansdell, Diane; Gregus, Krysten; Devereaux, P. J. (Wolters Kluwer Health, 2023)
    BACKGROUND: In prior analyses, myocardial injury after noncardiac surgery, major bleeding, and sepsis were independently associated with most deaths in the 30 days after noncardiac surgery, but most of these deaths occurred ...
  • Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study 
    Langhorne, Peter; O'Donnell, Martin J.; Chin, Siu Lim; Zhang, Hongye; Xavier, Denis; Avezum, Alvaro; Mathur, Nandini; Turner, Melanie; MacLeod, Mary Joan; Lopez-Jaramillo, Patricio; Damasceno, Albertino; Hankey, Graeme J.; Dans, Antonio L.; Elsayed, Ahmed; Mondo, Charles; Wasay, Mohammad; Czlonkowska, Anna; Weimar, Christian; Yusufali, Afzal Hussein; Hussain, Fawaz Al; Lisheng, Liu; Diener, Hans-Christoph; Ryglewicz, Danuta; Pogosova, Nana; Iqbal, Romana; Diaz, Rafael; Yusoff, Khalid; Oguz, Aytekin; Wang, Xingyu; Penaherrera, Ernesto; Lanas, Fernando; Ogah, Okechukwu S.; Ogunniyi, Adesola; Iversen, Helle K.; Málaga Rodríguez, Germán Javier; Rumboldt, Zvonko; Magazi, Daliwonga; Nilanont, Yongchai; Rosengren, Annika; Oveisgharan, Shahram; Yusuf, Salim; INTERSTROKE collaborators (Elsevier, 2018)
    BACKGROUND: Stroke disproportionately affects people in low-income and middle-income countries. Although improvements in stroke care and outcomes have been reported in high-income countries, little is known about practice ...
  • Prevalence of Pragmatically Defined High CV Risk and its Correlates in LMIC: A Report From 10 LMIC Areas in Africa, Asia, and South America 
    Carrillo Larco, Rodrigo Martín; Miranda, J. Jaime; Li, Xian; Cui, Chendi; Xu, Xiaolin; Ali, Mohammed; Alam, Dewan-S.; Gaziano, Thomas-A.; Gupta, Rajeev; Irazola, Vilma; Levitt, Naomi-S.; Prabhakaran, Dorairaj; Rubinstein, Adolfo; Steyn, Krisela; Tandon, Nikhil; Xavier, Denis; Wu, Yangfeng; Yan, Lijing-L. (Elsevier, 2016)
    BACKGROUND: Currently available tools for assessing high cardiovascular risk (HCR) often require measurements not available in resource-limited settings in low- and middle-income countries (LMIC). There is a need to assess ...
  • Renal Impairment and Risk of Acute Stroke: The INTERSTROKE Study. 
    Smyth, Andrew; Judge, Conor; Wang, Xingu; Pare, Guillaume; Rangarajan, Sumathy; Canavan, Michelle; Chin, Siu Lim; Al-Hussain, Fawaz; Yusufali, Afzalhussein M.; Elsayed, Ahmed; Damasceno, Albertino; Avezum, Alvaro; Czlonkowska, Anna; Rosengren, Annika; Dans, Antonio L.; Oguz, Aytekin; Mondo, Charles; Weimar, Christian; Ryglewicz, Danuta; Xavier, Denis; Lanas, Fernando; Málaga Rodríguez, Germán Javier; Hankey, Graeme J.; Iversen, Helle K.; Zhang, Hongye; Yusoff, Khalid; Pogosova, Nana; Lopez-Jamarillo, Patricio; Langhorne, Peter; Diaz, Rafael; Oveisgharan, Shahram; Yusuf, Salim; O'Donnell, Martin (Karger, 2021)
    BACKGROUND: Previous studies reported an association of renal impairment with stroke, but there are uncertainties underpinning this association. AIMS: We explored if the association is explained by shared risk factors or ...
  • Training and Capacity Building in LMIC for Research in Heart and Lung Diseases: The NHLBI-UnitedHealth Global Health Centers of Excellence Program 
    Bloomfield, Gerald S.; Xavier, Denis; Belis, Deshiree; Alam, Dewan; Davis, Patricia; Dorairaj, Prabhakaran; Ghannem, Hassen; Gilman, Robert Hugh; Kamath, Deepak; Kimaiyo, Sylvester; Levitt, Naomi; Martinez, Homero; Mejicano, Gabriela; Miranda, J. Jaime; Koehlmoos, Tracey Perez; Rabadan-Diehl, Cristina; Ramirez-Zea, Manuel; Rubinstein, Adolfo; Sacksteder, Katherine A.; Steyn, Krisela; Tandon, Nikhil; Vedanthan, Rajesh; Wolbach, Tracy; Wu, Yangfeng; Yan, Lijing L. (Elsevier, 2016)
    Stemming the tide of noncommunicable diseases (NCDs) worldwide requires a multipronged approach. Although much attention has been paid to disease control measures, there is relatively little consideration of the importance ...
  • Urinary Sodium and Potassium, and Risk of Ischemic and Hemorrhagic Stroke (INTERSTROKE): A Case-Control Study. 
    Judge, Conor; O'Donnell, Martin J.; Hankey, Graeme J.; Rangarajan, Sumathy; Chin, Siu Lim; Rao-Melacini, Purnima; Ferguson, John; Smyth, Andrew; Xavier, Denis; Lisheng, Liu; Zhang, Hongye; Lopez-Jaramillo, Patricio; Damasceno, Albertino; Langhorne, Peter; Rosengren, Annika; Dans, Antonio L.; Elsayed, Ahmed; Avezum, Alvaro; Mondo, Charles; Ryglewicz, Danuta; Czlonkowska, Anna; Pogosova, Nana; Weimar, Christian; Diaz, Rafael; Yusoff, Khalid; Yusufali, Afzalhussein; Oguz, Aytekin; Wang, Xingyu; Lanas, Fernando; Ogah, Okechukwu S.; Ogunniyi, Adesola; Iversen, Helle K.; Málaga Rodríguez, Germán Javier; Rumboldt, Zvonko; Oveisgharan, Shahram; Al Hussain, Fawaz; Yusuf, Salim (Oxford University Press, 2021)
    BACKGROUND: Although low sodium intake (<2 g/day) and high potassium intake (>3.5 g/day) are proposed as public health interventions to reduce stroke risk, there is uncertainty about the benefit and feasibility of this ...
  • Variations in knowledge, awareness and treatment of hypertension and stroke risk by country income level 
    O'Donnell, Martin; Hankey, Graeme J.; Rangarajan, Sumathy; Chin, Siu Lim; Rao-Melacini, Purnima; Ferguson, John; Xavier, Denis; Lisheng, Liu; Zhang, Hongye; Pais, Prem; Lopez-Jaramillo, Patricio; Damasceno, Albertino; Langhorne, Peter; Rosengren, Annika; Dans, Antonio L.; Elsayed, Ahmed; Avezum, Alvaro; Mondo, Charles; Smyth, Andrew; Judge, Conor; Diener, Hans-Christoph; Ryglewicz, Danuta; Czlonkowska, Anna; Pogosova, Nana; Weimar, Christian; Iqbal, Romana; Diaz, Rafael; Yusoff, Khalid; Yusufali, Afzalhussein; Oguz, Aytekin; Wang, Xingyu; Penaherrera, Ernesto; Lanas, Fernando; Ogah, Okechukwu Samuel; Ogunniyi, Adensola; Iversen, Helle K.; Málaga Rodríguez, Germán Javier; Rumboldt, Zvonko; Oveisgharan, Shahram; AlHussain, Fawaz; Daliwonga, Magazi; Nilanont, Yongchai; Yusuf, Salim (BMJ Publishing Group, 2020)
    Objective: Hypertension is the most important modifiable risk factor for stroke globally. We hypothesised that country-income level variations in knowledge, detection and treatment of hypertension may contribute to variations ...

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