Browsing by Subject "Adaptation, Physiological/genetics"

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Higher androgen bioactivity is associated with excessive erythrocytosis and chronic mountain sickness in Andean Highlanders: a review

Gonzales Rengifo, Gustavo Francisco; Chaupis, D. (Wiley, 2015)

Populations living at high altitudes (HA), particularly in the Peruvian Central Andes, are characterised by presenting subjects with erythrocytosis and others with excessive erythrocytosis (EE)(Hb>21 g dl(-1) ). EE is ...
New Insights into the Genetic Basis of Monge's Disease and Adaptation to High-Altitude

Stobdan, Tsering; Akbari, Ali; Azad, Priti; Zhou, Dan; Poulsen, Orit; Appenzeller, Otto; Gonzales Rengifo, Gustavo Francisco; Telenti, Amalio; Wong, Emily H. M.; Saini, Shubham; Kirkness, Ewen F.; Venter, J. Craig; Bafna, Vineet; Haddad, Gabriel G. (Oxford University Press, 2017)

Human high-altitude (HA) adaptation or mal-adaptation is explored to understand the physiology, pathophysiology, and molecular mechanisms that underlie long-term exposure to hypoxia. Here, we report the results of an ...

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