Browsing by Subject "Aminoquinolines/administration & dosage"

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Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study

Llanos Cuentas, Elmer Alejandro; Lacerda, Marcus V.; Rueangweerayut, Ronnatrai; Krudsood, Srivicha; Gupta, Sandeep K.; Kochar, Sanjay K.; Arthur, Preetam; Chuenchom, Nuttagarn; Möhrle, Jörg J.; Duparc, Stephan; Ugwuegbulam, Cletus; Kleim, Jörg-Peter; Carter, Nick; Green, Justin A.; Kellam, Lynda (Elsevier, 2014)

BACKGROUND: Clinical effectiveness of previous regimens to treat Plasmodium vivax infection have been hampered by compliance. We aimed to assess the dose-response, safety, and tolerability of single-dose tafenoquine plus ...

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