Browsing by Subject "DNA, Bacterial/chemistry/ultrastructure"

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New insights into the regulatory mechanisms of ppGpp and DksA on Escherichia coli RNA polymerase-promoter complex

Doniselli, Nicola; Rodriguez-Aliaga, Piere; Amidani, Davide; Bardales, Jorge A.; Bustamante, Carlos; Guerra Giraldez, Daniel; Rivetti, Claudio (Oxford University Press, 2015)

The stringent response modulators, guanosine tetraphosphate (ppGpp) and protein DksA, bind RNA polymerase (RNAP) and regulate gene expression to adapt bacteria to different environmental conditions. Here, we use Atomic ...

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