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Browsing by Subject "Rifampicin"

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Additional evidence to support the phasing-out of treatment category II regimen for pulmonary tuberculosis in Peru

Ponce, M.; Ugarte Gil, Cesar Augusto; Zamudio Fuertes, Carlos Eduardo; Krapp, F.; Gotuzzo Herencia, José Eduardo; Seas Ramos, Carlos Rafael (Oxford University Press, 2012)

The effectiveness of the World Health Organization's (WHO) treatment category II regimen for tuberculosis in 124 patients was compared to that of 1147 patients receiving treatment category I in Lima, Peru following WHO's ...
Antimicrobial resistance and molecular typing of Staphylococcus aureus bloodstream isolates from hospitals in Peru

García Apac, Coralith Marlinda; Rijnders, M.I.A.; Bruggeman, C.; Samalvides Cuba, Frine; Stobberingh, E.E.; Jacobs, J. (Elsevier, 2012)

Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) infections are of worldwide concern. The present study describes the antimicrobial resistance and molecular typing of methicillin-resistant and methicillin-susceptible ...
Clinical research and development of tuberculosis diagnostics: Moving from silos to synergy

Nahid, P.; Kim, P.S.; Evans, Carlton Anthony William; Alland, D.; Barer, M.; Diefenbach, J.; Ellner, J.; Hafner, R.; Hamilton, C.D.; Iademarco, M.F.; Ireton, G.; Kimerling, M.E.; Lienhardt, C.; MacKenzie, W.R.; Murray, M.; Perkins, M.D.; Posey, J.E.; Roberts, T.; Sizemore, C.; Stevens, W.S.; Via, L.; Williams, S.D.; Yew, W.W.; Swindells, S. (Oxford University Press, 2012)

The development, evaluation, and implementation of new and improved diagnostics have been identified as critical needs by human immunodeficiency virus (HIV) and tuberculosis researchers and clinicians alike. These needs ...
Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: A multicentre implementation study

Boehme, C.C.; Nicol, M.P.; Nabeta, P.; Michael, J.S.; Gotuzzo Herencia, José Eduardo; Tahirli, R.; Gler, M.T.; Blakemore, R.; Worodria, W.; Gray, C.; Huang, L.; Cáceres Nakiche, Tatiana; Mehdiyev, R.; Raymond, L.; Whitelaw, A.; Sagadevan, K.; Alexander, H.; Albert, H.; Cobelens, F.; Cox, H.; Alland, D.; Perkins, M.D. (Elsevier, 2011)

The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA) can detect tuberculosis and its multidrug-resistant form with very high sensitivity and specificity in controlled studies, but no performance data exist from district ...
HIV Coinfection Is Associated with low-fitness rpoB variants in rifampicin-resistant mycobacterium tuberculosis

Loiseau, C.; Brites, D.; Reinhard, M.; Zürcher, K.; Borrell, S.; Ballif, M.; Fenner, L.; Cox, H.; Rutaihwa, L.K.; Wilkinson, R.J.; Yotebieng, M.; Jane Carter, E.; Abimiku, A.; Marcy, O.; Gotuzzo Herencia, José Eduardo; Avihingsanon, A.; Zetola, N.; Doulla, B.; Böttger, E.C.; Egger, M.; Gagneux, S. (American Society for Microbiology, 2020)

We analyzed 312 drug-resistant genomes of Mycobacterium tuberculosis isolates collected from HIV-coinfected and HIV-negative TB patients from nine countries with a high tuberculosis burden. We found that rifampicin-resistant ...
Pharmacokinetics of rifampin in peruvian tuberculosis patients with and without comorbid diabetes or HIV

Requena-Méndez, A.; Davies, G.; Ardrey, A.; Jave, O.; López-Romero, S.L.; Ward, S.A.; Moore, David Alexander James (American Society for Microbiology, 2012)

For drug-compliant patients, poor responses to tuberculosis (TB) treatment might be attributable to subtherapeutic drug concentrations. An impaired absorption of rifampin was previously reported for patients with diabetes ...
Serial kinetics of the antibody response against the complete Brucella melitensis ORFeome in focal vertebral brucellosis

Cannella, A.P.; Lin, J.C.; Liang, L.; Atluri, V.; Gotuzzo Herencia, José Eduardo; Felgner, P.L.; Tsolis, R.M.; Vinetz, Joseph Michael (American Society for Microbiology, 2012)

Human brucellosis is a common zoonosis worldwide. Here we present a case of focal vertebral brucellosis in a 71-year-old Mexican-American woman who contracted infection from unpasteurized goat milk. Standard agglutination ...
Statistical analysis of 914 Mycobacterium tuberculosis genomes reveals single nucleotide polymorphisms in the ponA1 gene associated with rifampicin resistance

Rabanal Sánchez, Jhonatan (Springer, 2023)

Rifampicin resistance in Mycobacterium tuberculosis represents a big public health problem and the ponA1 gene could be related to this. Our study analyzed three secondary databases of 914 M. tuberculosis genomes, which ...
Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents

Camacho, J.; Barazarte, A.; Gamboa, N.; Rodrigues, J.; Rojas, R.; Vaisberg Wollach, Abraham Jaime; Gilman, Robert Hugh; Charris, J. (Elsevier, 2011)

A series of N′-substituted-2-(5-nitrofuran or 5-nitrothiophen-2-yl)- 3H-benzo[d]imidazole-5-carbohydrazide derivatives were synthesized and investigated for their abilities to inhibit β-hematin formation, hemoglobin ...

Browsing by Subject "Rifampicin"

Browsing by Subject "Rifampicin"

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