Browsing by Subject "bone morphogenetic protein 6"

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Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly

Gammella, Elena; Diaz, Victor; Recalcati, Stefania; Buratti, Paolo; Samaja, Michele; Dey, Soumyadeep; Noguchi, Constance Tom; Gassmann, Max; Cairo, Gaetano (American Physiological Society, 2015)

Under conditions of accelerated erythropoiesis, elevated erythropoietin (Epo) levels are associated with inhibition of hepcidin synthesis, a response that ultimately increases iron availability to meet the enhanced iron ...
Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice

Díaz, Víctor; Gammella, Elena; Recalcati, Stefania; Santambrogio, Paolo; Naldi, Arianne Monge; Vogel, Johannes; Gassmann, Max; Cairo, Gaetano (Wiley, 2013)

The liver-derived peptide hepcidin controls the balance between iron demand and iron supply. By inhibiting the iron export activity of ferroportin, hepcidin modulates iron absorption and delivery from the body's stores. ...

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