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Browsing by Author "Bustos, Javier A."

Browsing by Author "Bustos, Javier A."

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  • Arroyo, Gianfranco; Bustos, Javier A.; Lescano, Andres G.; Gonzales, Isidro; Saavedra, Herbert; Rodriguez, Silvia; Pretell, E. Javier; Bonato, Pierina S.; Lanchote, Vera L.; Takayanagui, Osvaldo M.; Horton, John; Gonzalez, Armando E.; Gilman, Robert H.; Garcia, Hector H. (Oxford University Press, 2019)
    Background: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable ...
  • Arroyo, Gianfranco; Rodriguez, Silvia; Lescano, Andres G.; Alroy, Karen A.; Bustos, Javier A.; Santivañez, Saul; Gonzales, Isidro; Saavedra, Herbert; Pretell, E. Javier; Gonzalez, Armando E.; Gilman, Robert H.; Tsang, Victor C. W.; Garcia, Hector H.; Cysticercosis Working Group in Peru (Oxford University Press, 2018)
    Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections ...
  • Duque, Kevin R.; Escalaya, Alejandro L.; Zapata, Willy; Burneo, Jorge G.; Bustos, Javier A.; Gonzales, Isidro; Saavedra, Herbert; Pretell, E. Javier; Garcia, Hector H.; Cysticercosis Working Group in Peru (Elsevier, 2018)
    OBJECTIVE: Discordances between imaging findings of parenchymal neurocysticercosis and seizure expression have been reported, and as such the possibility that neurocysticercosis and seizures may frequently coexist by chance ...
  • Garcia, Hector H.; Gonzales, Isidro; Bustos, Javier A.; Saavedra, Herbert; Gavidia, Martin; Rodriguez, Lourdes; Najar, Enrique; Umeres, Hugo; Pretell, E. Javier (Elsevier, 2015)
    We thank Aba Mahamat and colleagues for their comments on our Article1 and patient data illustrating a difficult case successfully treated with combined albendazole and praziquantel. We do not deem use of the combination ...
  • Garcia, Hector H.; Lescano, Andres G.; Gonzales, Isidro; Bustos, Javier A.; Pretell, E. Javier; Horton, John; Saavedra, Herbert; Gonzalez, Armando E.; Gilman, Robert H. (Oxford University Press, 2016)
    Background. The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 ...
  • Nash, Theodore E.; Bustos, Javier A.; Garcia, Hector H. (Elsevier, 2017)
    Taenia solium (the pork tapeworm) is present in most developing countries, where it is a frequent cause of seizures and other neurological disease. Parasitic larvae invade the human brain, establish, and eventually resolve, ...
  • Abraham, Annette; Bustos, Javier A.; Carabin, Hélène; de Meijere, Robert; Sahu, Priyadarshi S.; Rajshekhar, Vedantam; Singh, Gagandeep; White, A. Clinton Jr; Chiodini, Peter L.; Gabriël, Sarah; Homeida, Mamoun; Nash, Theodore; Ngowi, Bernard; Zhou, Xiao Nong; Coyle, Christina; Garcia, Hector H.; Winkler, Andrea S. (PLoS, 2021)
    Single brain enhancing lesions (SEL) are the most common presentation of neurocysticercosis (NCC) observed on neuroimaging in people presenting with epileptic seizures not only on the Indian sub-continent and in travelers ...
  • Garcia, Hector H.; Gonzales, Isidro; Lescano, Andres G.; Bustos, Javier A.; Zimic, Mirko; Escalante, Diego; Saavedra, Herbert; Gavidia, Martin; Rodriguez, Lourdes; Najar, Enrique; Umeres, Hugo; Pretell, E. Javier (Elsevier, 2014)
    BACKGROUND: Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs ...
  • Garcia, Hector H.; Gonzales, Isidro; Lescano, Andres G.; Bustos, Javier A.; Zimic, Mirko; Escalante, Diego; Saavedra, Herbert; Gavidia, Martin; Rodriguez, Lourdes; Najar, Enrique; Umeres, Hugo; Pretell, E. Javier (Elsevier, 2014)
    Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs would ...
  • Garcia, Hector H.; Gonzales, Isidro; Lescano, Andres G.; Bustos, Javier A.; Pretell, E.Javier; Saavedra, Herbert; Nash, Theodore E.; The Cysticercosis Working Group in Peru (Wiley, 2014)
    Objective: Neurocysticercosis (NCC) is a major cause of seizures and epilepsy in endemic countries. Antiparasitic treatment of brain cysts leads to seizures due to the host's inflammatory reaction, requiring concomitant ...
  • Bustos, Javier A.; Arroyo, Gianfranco; Gilman, Robert H.; Soto-Becerra, Percy; Gonzales, Isidro; Saavedra, Herbert; Pretell, E. Javier; Nash, Theodore E.; O'Neal, Seth E.; Del Brutto, Oscar H.; Gonzalez, Armando E.; Garcia, Hector H.; Cysticercosis Working Group in Peru (Oxford University Press, 2020)
    BACKGROUND: Neurocysticercosis (NCC) is a major cause of acquired epilepsy in most of the world. Larval cysts in the human brain eventually resolve and either disappear or leave a calcified scar that is associated with ...
  • Bustos, Javier A.; Arroyo, Gianfranco; Gilman, Robert H.; Soto-Becerra, Percy; Gonzales, Isidro; Saavedra, Herbert; Pretell, E. Javier; Nash, Theodore E.; O'Neal, Seth E.; Del Brutto, Oscar H.; Gonzalez, Armando E.; Garcia, Hector H. (Oxford University Press, 2021)
    BACKGROUND: Neurocysticercosis is a major cause of acquired epilepsy. Larval cysts in the human brain eventually resolve and either disappear or leave a calcification that is associated with seizures. In this study, we ...
  • Herrick, Jesica A.; Maharathi, Biswajit; Kim, Jin Suh; Abundis, Gerardo G.; Garg, Anjali; Gonzales, Isidro; Saavedra, Herbert; Bustos, Javier A.; Garcia, Hector H.; Loeb, Jeffrey A.; Cysticercosis Working Group in Peru (Wiley, 2018)
    Objective: We conducted a retrospective, case-control study of neurocysticercosis patients to ascertain early markers that identify subjects likely to develop treatment-resistant seizures. Methods: Clinical histories and ...
  • Garcia, Hector H.; Castillo, Yesenia; Gonzales, Isidro; Bustos, Javier A.; Saavedra, Herbert; Jacob, Louis; Del Brutto, Oscar H.; Wilkins, Patricia P.; Gonzalez, Armando E.; Gilman, Robert H.; Cysticercosis Working Group in Peru (Wiley, 2018)
    OBJECTIVE: To evaluate the diagnostic performance of two commercially available ELISA kits, Novalisa® and Ridascreen® , for the detection of antibodies to Taenia solium, compared to serological diagnosis of neurocysticercosis ...
  • Abanto, Jesús; Blanco, D.; Saavedra, Herbert; Gonzales, Isidro; Siu, Diego; Pretell, E. Javier; Bustos, Javier A.; Garcia, Hector H.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2021)
    Neurocysticercosis (NCC) is endemic in many parts of the world, carrying significant neurological morbidity that varies according to whether lesions are located inside the cerebral parenchyma or in extraparenchymal spaces. ...
  • Jewell, Paul D.; Abraham, Annette; Schmidt, Veronika; Buell, Kevin G.; Bustos, Javier A.; Garcia, Hector H.; Dixon, Matthew A.; Walker, Martin; Ngowi, Bernard J.; Basanez, Maria-Gloria; Winkler, Andrea S. (Wiley, 2021)
    Objectives Neurocysticercosis (NCC) and human immunodeficiency virus (HIV) have a high disease burden and are prevalent in overlapping low- and middle-income areas. Yet, treatment guidance for people living with HIV/AIDS ...
  • Bustos, Javier A.; Gonzales, Isidro; Saavedra, Herbert; Handali, Sukwan; Garcia, Hector H.; Cysticercosis Working Group in Peru (Elsevier, 2021)
    Neurocysticercosis is endemic in most of the world and in endemic areas it accounts for approximately 30% of cases of epilepsy. Appropriate diagnosis and management of neurocysticercosis requires understanding the diverse ...
  • Cangalaya, Carla; Bustos, Javier A.; Calcina, Juan; Vargas-Calla, Ana; Mamani, Javier; Suarez, Diego; Arroyo, Gianfranco; Gonzalez, Armando E.; Chacaltana, Juan; Guerra-Giraldez, Cristina; Mahanty, Siddhartha; Nash, Theodore E.; Garcia, Hector H. (PLoS, 2017)
    Background: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation ...
  • Bustos, Javier A.; García, Hector H.; Del Brutto, Oscar H. (American Society of Tropical Medicine and Hygiene, 2017)
    Intraventricular neurocysticercosis (NCC) is a severe form of NCC requiring prompt diagnosis and treatment. We aimed to assess the reliability of the most recent version of diagnostic criteria for this form of NCC. Two ...
  • Bustos, Javier A.; García, Héctor H.; Del Brutto, Oscar H. (American Society of Tropical Medicine and Hygiene, 2017)
    In the letter “Reproducibility of Diagnostic Criteria for Ventricular Neurocysticercosis,” the authors manifest their unhappiness with the results of the systematic review we conducted to assess reliability of the revised ...

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