Listar por autor "Cangalaya, Carla"

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  • Disruption of the blood-brain barrier in pigs naturally infected with Taenia solium, untreated and after anthelmintic treatment 
    Guerra-Giraldez, Cristina; Marzal, Miguel; Cangalaya, Carla; Balboa, Diana; Orrego Solano, Miguel Ángel; Paredes, Adriana; Gonzales-Gustavson, Eloy; Arroyo Hurtado, Gianfranco; García Lescano, Héctor Hugo; Gonzalez Zariquiey, Armando Emiliano; Mahanty, Siddhartha; Nash, Theodore E. (Elsevier, 2013)
    Neurocysticercosis is a widely prevalent disease in the tropics that causes seizures and a variety into of neurological symptoms in most of the world. Experimental models are limited and do not allow assessment of the ...
  • Evans blue staining reveals vascular leakage associated with focal areas of host-parasite interaction in brains of pigs infected with Taenia solium 
    Marzal, Miguel; Guerra-Giraldez, Cristina; Paredes, Adriana; Cangalaya, Carla; Rivera, Andrea; Gonzalez Zariquiey, Armando Emiliano; Mahanty, Siddhartha; García Lescano, Héctor Hugo; Nash, Theodore E. (Public Library of Science, 2014)
    Cysticidal drug treatment of viable Taenia solium brain parenchymal cysts leads to an acute pericystic host inflammatory response and blood brain barrier breakdown (BBB), commonly resulting in seizures. Naturally infected ...
  • Experimental brain infection with cysticercosis in sheep 
    Sota Ortecho, K. A.; Bustos Palomino, Javier Arturo; Verastegui Pimentel, Manuela Renee; Toribio, Luz; Chile Andrade, Nancy; Angulo, Noelia; Cangalaya, Carla; Calcina, J.; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh; García Lescano, Héctor Hugo (Instituto Nacional de Salud, 2022)
    Objective. To explore the feasibility of developing a sheep model of neurocysticercosis (NCC) by intracranial infection with T. solium oncospheres. Materials and methods. We carried out an experimental infection model of ...
  • Inflammation Caused by Praziquantel Treatment Depends on the Location of the Taenia solium Cysticercus in Porcine Neurocysticercosis 
    Cangalaya, Carla; Zimic-Peralta, Mirko Juan; Marzal, Miguel; Gonzalez Zariquiey, Armando Emiliano; Guerra-Giraldez, Cristina; Mahanty, Siddhartha; Nash, Theodore E.; García Lescano, Héctor Hugo (Public Library of Science, 2015)
    BACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. ...
  • Mathematical algorithm for the automatic recognition of intestinal parasites 
    Alva, Alicia; Cangalaya, Carla; Quiliano, Miguel; Krebs, Casey; Gilman, Robert Hugh; Sheen Cortavarria, Patricia; Zimic-Peralta, Mirko Juan (Public Library of Science, 2017)
    Parasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical ...
  • Perilesional Inflammation in Neurocysticercosis - Relationship Between Contrast-Enhanced Magnetic Resonance Imaging, Evans Blue Staining and Histopathology in the Pig Model 
    Cangalaya, Carla; Bustos Palomino, Javier Arturo; Calcina, Juan; Vargas-Calla, Ana; Suarez, Diego; Gonzalez Zariquiey, Armando Emiliano; Chacaltana, Juan; Guerra-Giraldez, Cristina; Mahanty, Siddhartha; Nash, Theodore-E.; García Lescano, Héctor Hugo (Public Library of Science, 2016)
    BACKGROUND: Disease manifestations in neurocysticercosis (NCC) are frequently due to inflammation of degenerating Taenia solium brain cysts. Exacerbated inflammation post anthelmintic treatment is associated with leakage ...
  • Post-treatment vascular leakage and inflammatory responses around brain cysts in porcine neurocysticercosis 
    Mahanty, Siddhartha; Orrego Solano, Miguel Ángel; Mayta, Holger; Marzal, Miguel; Cangalaya, Carla; Paredes, Adriana; Gonzales-Gustavson, Eloy; Arroyo Hurtado, Gianfranco; Gonzalez Zariquiey, Armando Emiliano; Guerra-Giraldez, Cristina; García Lescano, Héctor Hugo; Nash, Theodore E. (Public Library of Science, 2015)
    Cysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. ...
  • Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole 
    Cangalaya, Carla; Bustos Palomino, Javier Arturo; Calcina, Juan; Vargas-Calla, Ana; Mamani, Javier; Suarez, Diego; Arroyo Hurtado, Gianfranco; Gonzalez Zariquiey, Armando Emiliano; Chacaltana, Juan; Guerra-Giraldez, Cristina; Mahanty, Siddhartha; Nash, Theodore E.; García Lescano, Héctor Hugo (Public Library of Science, 2017)
    Background: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation ...
  • TNF-α blockade suppresses pericystic inflammation following anthelmintic treatment in porcine neurocysticercosis 
    Mahanty, Siddhartha; Orrego Solano, Miguel Ángel; Cangalaya, Carla; Adrianzen, M. Paz; Arroyo Hurtado, Gianfranco; Calcina, Juan; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; Guerra-Giraldez, Cristina; Nash, Theodore E.; Cysticercosis Working Group in Peru (Public Library of Science, 2017)
    BACKGROUND: Neurocysticercosis (NCC) is an infection of the brain with the larval cyst of the tapeworm, Taenia solium. Cysticidal treatment induces parasite killing resulting in a post inflammatory response and seizures, ...

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