Listar por autor "Conn, Jan E."

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Bionomics of malaria vectors in hyperendemic transmission areas of the Peruvian Amazon

Herrera-Varela, Manuela; Manrique, Edgar; Saavedra, Marlon; Vinetz, Joseph; Conn, Jan E. (Universidad Peruana Cayetano Heredia, 2019)

La transmisión de la malaria en la Amazonía Peruana es causada principalmente por Plasmodium vivax y transmitida por Nyssorhynchus (previamente Anopheles) darlingi. La ecología larval de esta especie y su relación con la ...
Changes in Genetic Diversity from Field to Laboratory During Colonization of Anopheles darlingi Root (Diptera: Culicidae)

Lainhart, William; Bickersmith, Sara A.; Moreno, Marta; Rios, Carlos Tong; Vinetz, Joseph Michael; Conn, Jan E. (American Society of Tropical Medicine and Hygiene, 2015)

The process of colonizing any arthropod species, including vector mosquitoes, necessarily involves adaptation to laboratory conditions. The adaptation and evolution of colonized mosquito populations needs consideration ...
Ecology and larval population dynamics of the primary malaria vector Nyssorhynchus darlingi in a high transmission setting dominated by fish farming in western Amazonian Brazil

Rufalco-Moutinho, Paulo; Moura Kadri, Samir; Peres Alonso, Diego; Moreno, Marta; Carrasco Escobar, Gabriel; Prussing, Catharine; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael; Mureb Sallum, Maria Anice; Conn, Jan E.; Martins Ribolla, Paulo Eduardo (Public Library of Science, 2021)

Vale do Rio Jurua in western Acre, Brazil, is a persistent malaria transmission hotspot partly due to fish farming development that was encouraged to improve local standards of living. Fish ponds can be productive breeding ...
Evidence for temporal population replacement and the signature of ecological adaptation in a major Neotropical malaria vector in Amazonian Peru

Lainhart, William; Bickersmith, Sara A.; Nadler, Kyle J.; Moreno, Marta; Saavedra Romero, Marlon Pierino; Chu, Virginia M.; Ribolla, Paulo E.; Vinetz, Joseph Michael; Conn, Jan E. (BioMed Central, 2015)

BACKGROUND: The major Neotropical malaria vector, Anopheles darlingi, was reintroduced into the Iquitos, Loreto, Peru area during the early 1990s, where it displaced other anophelines and caused a major malaria epidemic. ...
Evidence-Based Malaria Control and Elimination in the Amazon: Input from the International Center of Excellence in Malaria Research Network in Peru and Brazil.

Ferreira, Marcelo U.; Gamboa Vilela, Dionicia Baziliza; Torres Fajardo, Katherine Jessica; Rodriguez-Ferrucci, Hugo; Soto-Calle, Veronica E.; Pardo, Karim; Fontoura, Pablo S.; Tomko, Sheena S.; Gazzinelli, Ricardo T.; Conn, Jan E.; Castro, Marcia C.; Llanos Cuentas, Elmer Alejandro; Vinetz, Joseph Michael (American Journal of Tropical Medicine and Hygiene, 2022)

Malaria remains endemic in 17 countries in the Americas, where 723,000 cases were reported in 2019. The majority (> 90%) of the regional malaria burden is found within the Amazon Basin, which includes nine countries and ...
High-accuracy detection of malaria vector larval habitats using drone-based multispectral imagery

Carrasco Escobar, Gabriel; Manrique, Edgar; Ruiz Cabrejos, Jorge; Saavedra Romero, Marlon Pierino; Alava, Freddy; Bickersmith, Sara; Prussing, Catharine; Vinetz, Joseph Michael; Conn, Jan E.; Moreno, Marta; Gamboa Vilela, Dionicia Baziliza (Public Library of Science, 2019)

Interest in larval source management (LSM) as an adjunct intervention to control and eliminate malaria transmission has recently increased mainly because long-lasting insecticidal nets (LLINs) and indoor residual spray ...
Higher risk of malaria transmission outdoors than indoors by Nyssorhynchus darlingi in riverine communities in the Peruvian Amazon.

Saavedra Romero, Marlon Pierino; Conn, Jan E.; Alava, Freddy; Carrasco Escobar, Gabriel; Prussing, Catharine; Bickersmith, Sara A.; Sangama, Jorge L.; Fernandez-Minope, Carlos; Guzman Guzman, Mitchel Anthony; Tong, Carlos; Valderrama, Carlos; Vinetz, Joseph Michael; Gamboa Vilela, Dionicia Baziliza; Moreno, Marta (BioMed Central, 2019)

BACKGROUND: Malaria remains an important public health problem in Peru where incidence has been increasing since 2011. Of over 55,000 cases reported in 2017, Plasmodium vivax was the predominant species (76%), with P. ...
Implications for changes in Anopheles darlingi biting behaviour in three communities in the peri-Iquitos region of Amazonian Peru

Moreno, Marta; Saavedra Romero, Marlon Pierino; Bickersmith, Sara A.; Lainhart, William; Tong, Carlos; Alava, Freddy; Vinetz, Joseph Michael; Conn, Jan E. (BioMed Central, 2015)

BACKGROUND: Malaria transmission in the peri-Iquitos region of Amazonian Peru has been designated as seasonal and hypo-endemic with recently described hyper-endemic hotspots. Despite relatively recent distribution of ...
Infection of laboratory-colonized Anopheles darlingi mosquitoes by Plasmodium vivax

Moreno, Marta; Tong, Carlos; Guzman Guzman, Mitchel Anthony; Chuquiyauri, Raul; Llanos Cuentas, Elmer Alejandro; Rodriguez, Hugo; Gamboa Vilela, Dionicia Baziliza; Meister, Stephan; Winzeler, Elizabeth A.; Maguina, Paula; Conn, Jan E.; Vinetz, Joseph Michael (American Society of Tropical Medicine and Hygiene, 2014)

Anopheles darlingi Root is the most important malaria vector in the Amazonia region of South America. However, continuous propagation of An. darlingi in the laboratory has been elusive, limiting entomological, genetic/genomic, ...
Insecticide Resistance in Areas Under Investigation by the International Centers of Excellence for Malaria Research: A Challenge for Malaria Control and Elimination

Quinones, Martha L.; Norris, Douglas E.; Conn, Jan E.; Moreno, Marta; Burkot, Thomas R.; Bugoro, Hugo; Keven, John B.; Cooper, Robert; Yan, Guiyun; Rosas, Angel; Palomino, Miriam; Donnelly, Martin J.; Mawejje, Henry D.; Eapen, Alex; Montgomery, Jacqui; Coulibaly, Mamadou B.; Beier, John C.; Kumar, Ashwani (American Society of Tropical Medicine and Hygiene, 2015)

Scale-up of the main vector control interventions, residual insecticides sprayed on walls or structures and/or impregnated in bed nets, together with prompt diagnosis and effective treatment, have led to a global reduction ...
Insights into Plasmodium vivax Asymptomatic Malaria Infections and Direct Skin-Feeding Assays to Assess Onward Malaria Transmission in the Amazon

Moreno, Marta; Torres Fajardo, Katherine Jessica; Tong, Carlos; Castillo, Stefano S. Garcia; Carrasco Escobar, Gabriel; Guedez, Gerson; Torres, Lutecio; Herrera Varela, Manuela; Guerra, Layne; Guzman Guzman, Mitchel Anthony; Wong, Daniel; Ramirez, Roberson; Llanos Cuentas, Elmer Alejandro; Conn, Jan E.; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael (American Journal of Tropical Medicine and Hygiene, 2022)

Understanding the reservoir and infectivity of Plasmodium gametocytes to vector mosquitoes is crucial to align strategies aimed at malaria transmission elimination. Yet, experimental information is scarce regarding the ...
Integrating Parasitological and Entomological Observations to Understand Malaria Transmission in Riverine Villages in the Peruvian Amazon.

Rosas-Aguirre, Angel; Moreno, Marta; Moreno-Gutierrez, Diamantina; Llanos Cuentas, Elmer Alejandro; Saavedra Romero, Marlon Pierino; Contreras-Mancilla, Juan; Barboza, Jose; Alava, Freddy; Aguirre, Kristhian; Carrasco Escobar, Gabriel; Prussing, Catharine; Vinetz, Joseph Michael; Conn, Jan E.; Speybroeck, Niko; Gamboa Vilela, Dionicia Baziliza (Oxford University Press, 2021)

BACKGROUND: Remote rural riverine villages account for most of the reported malaria cases in the Peruvian Amazon. As transmission decreases due to intensive standard control efforts, malaria strategies in these villages ...
Intensive trapping of blood-fed Anopheles darlingi in Amazonian Peru reveals unexpectedly high proportions of avian blood-meals

Moreno, Marta; Saavedra Romero, Marlon Pierino; Bickersmith, Sara A.; Prussing, Catharine; Michalski, Adrian; Tong Rios, Carlos; Vinetz, Joseph Michael; Conn, Jan E. (Public Library of Science, 2017)

Anopheles darlingi, the main malaria vector in the Neotropics, has been considered to be highly anthropophilic. However, many behavioral aspects of this species remain unknown, such as the range of blood-meal sources. ...
Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil

Torres Fajardo, Katherine Jessica; Ferreira, Marcelo U.; Castro, Marcia C.; Escalante, Ananias A.; Conn, Jan E.; Villasis Mayuri, Elizabeth Melisa; da Silva Araujo, Maisa; Almeida, Gregorio; Rodrigues, Priscila T.; Corder, Rodrigo M.; Fernandes, Anderson R. J.; Calil, Priscila R.; Ladeia, Winni A.; Garcia-Castillo, Stefano S.; Gomez, Joaquin; do Valle Antonelli, Lis Ribeiro; Gazzinelli, Ricardo T.; Golenbock, Douglas T.; Llanos Cuentas, Elmer Alejandro; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael (American Journal of Tropical Medicine and Hygiene, 2022)

The 1990s saw the rapid reemergence of malaria in Amazonia, where it remains an important public health priority in South America. The Amazonian International Center of Excellence in Malaria Research (ICEMR) was designed ...
Malaria vector species in amazonian Peru co-occur in larval habitats but have distinct larval microbial communities

Prussing, Catharine; Saavedra Romero, Marlon Pierino; Bickersmith, Sara A.; Alava, Freddy; Guzman Guzman, Mitchel Anthony; Manrique, Edgar; Carrasco Escobar, Gabriel; Moreno, Marta; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael; Conn, Jan E. (Public Library of Science, 2019)

In Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source ...
Microgeographical structure in the major Neotropical malaria vector Anopheles darlingi using microsatellites and SNP markers

Campos, Melina; Conn, Jan E.; Alonso, Diego Peres; Vinetz, Joseph Michael; Emerson, Kevin J.; Ribolla, Paulo Eduardo Martins (BioMed Central, 2017)

BACKGROUND: In recent decades, throughout the Amazon Basin, landscape modification contributing to profound ecological change has proceeded at an unprecedented rate. Deforestation that accompanies human activities can ...
Mutations Linked to Insecticide Resistance Not Detected in the Ace-1 or VGSC Genes in Nyssorhynchus darlingi from Multiple Localities in Amazonian Brazil and Peru

Bickersmith, Sara A.; Jurczynski, John D.; Sallum, Maria Anice Mureb; Chaves, Leonardo S. M.; Bergo, Eduardo S.; Rodriguez, Gloria A. D.; Morante, Clara A.; Rios, Carlos T.; Saavedra Romero, Marlon Pierino; Alava, Freddy; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael; Conn, Jan E. (MDPI, 2023)

Indoor residual spray (IRS), mainly employing pyrethroid insecticides, is the most common intervention for preventing malaria transmission in many regions of Latin America; the use of long-lasting insecticidal nets (LLINs) ...
Natural Infection of Nyssorhynchus darlingi and Nyssorhynchus benarrochi B with Plasmodium during the Dry Season in the Understudied Low-Transmission Setting of Datem del Marañon Province, Amazonian Peru.

Conn, Jan E.; Bickersmith, Sara A.; Saavedra Romero, Marlon Pierino; Morales Monje, Juliana Andrea; Alava, Freddy; Diaz Rodriguez, Gloria A.; Del Aguila Morante, Clara R.; Tong, Carlos G.; Alvarez-Antonio, Carlos; Daza Huanahui, Jesus M.; Vinetz, Joseph Michael; Gamboa Vilela, Dionicia Baziliza (American Journal of Tropical Medicine and Hygiene, 2023)

The persistence of malaria hotspots in Datem del Marañon Province, Peru, prompted vector control units at the Ministry of Health, Loreto Department, to collaborate with the Amazonian International Center of Excellence for ...
New Records of Anopheles benarrochi B (Diptera: Culicidae) in Malaria Hotspots in the Amazon Regions of Ecuador and Peru

Morales Viteri, Diego; Herrera Varela, Manuela; Albuja, Maribel; Quiroga, Cristina; Diaz, Gloria; Del Aguila Morante, Clara; Ramirez, Dario; Vinetz, Joseph Michael; Bickersmith, Sara A.; Conn, Jan E. (Oxford University Press, 2021)

The increase in malaria transmission in the Amazon region motivated vector control units of the Ministry of Health of Ecuador and Peru to investigate Anopheles (Diptera: Culicidae) species present in transmission hotspots. ...
Nyssorhynchus darlingi genome-wide studies related to microgeographic dispersion and blood-seeking behavior

Alvarez, Marcus Vinicius Nis; Alonso, Diego Peres; Kadri, Samir Moura; Rufalco-Moutinho, Paulo; Bernardes, Isabella Adriadne Ferrari; de Mello, Ana Carolina Florindo; Souto, Ana Carolina; Carrasco Escobar, Gabriel; Moreno, Marta; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael; Conn, Jan E.; Ribolla, Paulo E.M. (BioMed Central, 2022)

Background: In Brazil, malaria is concentrated in the Amazon Basin, where more than 99% of the annual cases are reported. The main goal of this study was to investigate the population structure and genetic association of ...