Listar por autor "Dorny, Pierre"

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Consistent Measurement of Parasite-Specific Antigen Levels in Sera of Patients with Neurocysticercosis Using Two Different Monoclonal Antibody (mAb)-Based Enzyme-Linked Immunosorbent Assays.

Castillo Berrios, Yesenia; Toribio Salazar, Luz Milagros; Guzmán Dueñas, Carolina del Rosario; Arroyo Hurtado, Gianfranco; Espinoza Guerrero, Cindy; Saavedra, Herbert; Bustos Palomino, Javier Arturo; Dorny, Pierre; O'Neal, Seth E.; García Lescano, Héctor Hugo (MDPI, 2023)

Monoclonal antibody (mAb)-based enzyme-linked immunosorbent assay (ELISA) is a complementary diagnosis technique for neurocysticercosis (NCC), which detects circulating parasite antigen (Ag) indicative of viable infection ...
Evaluation of cross-reactivity to Taenia hydatigena and Echinococcus granulosus in the enzyme-linked immunoelectrotransfer blot assay for the diagnosis of porcine cysticercosis

Gomez-Puerta, Lucho; Vargas-Calla, Ana; Castillo Berrios, Yesenia; Lopez-Urbina, Maria Teresa; Dorny, Pierre; García Lescano, Héctor Hugo; Gonzalez Zariquiey, Armando Emiliano; O'Neal, Seth E. (BioMed Central, 2019)

BACKGROUND: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to ...
Improved diagnosis of viable parenchymal neurocysticercosis by combining antibody banding patterns on enzyme-linked immunoelectrotransfer blot (EITB) with antigen ELISA assay.

Arroyo Hurtado, Gianfranco; Bustos Palomino, Javier Arturo; Lescano Guevara, Andres Guillermo; Gonzales, Isidro; Saavedra Pastor, Herbert; Pretell, E. Javier; Castillo Berrios, Yesenia; Perez, Erika; Handali, Sukwan; Noh, John; Dorny, Pierre; Gilman, Robert Hugh; O'Neal, Seth E.; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo (American Society for Microbiology, 2022)

The diagnosis of neurocysticercosis (NCC) depends on neuroimaging and serological confirmation. While antibody detection by enzyme-linked immunoelectrotransfer blot (EITB) fails to predict viable NCC, EITB banding patterns ...
In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against taenia solium

Paredes, Adriana; de Campos Lourenço, Tiago; Marzal, Miguel; Rivera, Andrea; Dorny, Pierre; Mahanty, Siddhartha; Guerra-Giraldez, Cristina; García Lescano, Héctor Hugo; Nash, Theodore E.; Cass, Quezia B. (American Society for Microbiology, 2013)

Albendazole is an anthelmintic drug widely used in the treatment of neurocysticercosis (NCC), an infection of the brain with Taenia solium cysts. However, drug levels of its active metabolite, albendazole sulfoxide (ABZSO), ...
Incidence of human Taenia solium larval Infections in an Ecuadorian endemic area: implications for disease burden assessment and control

Coral-Almeida, Marco; Rodríguez-Hidalgo, Richar; Celi-Erazo, Maritza; García Lescano, Héctor Hugo; Rodríguez, Silvia; Devleesschauwer, Brecht; Benítez-Ortiz, Washington; Dorny, Pierre; Praet, Nicolas (Public Library of Science, 2014)

BACKGROUND: Human cysticercosis is a zoonotic disease causing severe health disorders and even death. While prevalence data become available worldwide, incidence rate and cumulative incidence figures are lacking, which ...
Movements of free-range pigs in rural communities in Zambia: an explorative study towards future ring interventions for the control of Taenia solium

Van Damme, Inge; Pray, Ian; Mwape, Kabemba E.; Trevisan, Chiara; Coudenys, Fien; Mubanga, Chisimba; Mwelwa, Chembesofu; Vaernewyck, Victor; Dorny, Pierre; O’Neal, Seth E.; Gabriël, Sarah (BioMed Central, 2022)

Background: Taenia solium typically affects resource-poor communities where pigs are allowed to roam freely, and sanitation and hygiene levels are suboptimal. Sustainable, long-term strategies are urgently needed to control ...
Neurocysticercosis in Bhutan: a cross-sectional study in people with epilepsy

Brizzi, Kate; Pelden, Sonam; Tshokey, Tshokey; Nirola, Damber K.; Diamond, Megan B.; Klein, Joshua P.; Tshering, Lhab; Deki, Sonam; Nidup, Dechen; Bruno, Veronica; Dorny, Pierre; Hugo Garcia, Hector; Mateen, Farrah J.; Bhutan Epilepsy Project (Oxford University Press, 2016)

Background: We sought to provide an assessment of the burden of neurocysticercosis among people with epilepsy (PWE) in Bhutan and evaluate the yield of various tests for Taenia solium. Methods: PWE were enrolled at the ...
Parasite antigen in serum predicts the presence of viable brain parasites in patients with apparently calcified cysticercosis only

Zea-Vera, Alonsa; Cordova, Erika G.; Rodriguez, Silvia; Gonzales, Isidro; Pretell, E.Javier; Castillo Berrios, Yesenia; Castro-Suarez, Sheila; Gabriël, Sarah; Tsang, Victor C.W.; Dorny, Pierre; García Lescano, Héctor Hugo (Oxford University Press, 2013)

Computed tomography (CT) remains the standard neuroimaging screening exam for neurocysticercosis, and residual brain calcifications are the commonest finding. Magnetic resonance imaging (MRI) is more sensitive than CT but ...
Porcine Cysticercosis: Possible Cross-Reactivity of Taenia hydatigena to GP50 Antigen in the Enzyme-Linked Immunoelectrotransfer Blot Assay

Muro Ecca, Claudio Alberto; Gomez-Puerta, Luis A.; Flecker, Robert H.; Gamboa Morán, Ricardo; Barreto, Percy Vilchez; Dorny, Pierre; Tsang, Victor C. W.; Gilman, Robert Hugh; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; O'Neal, Seth E.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2017)

The lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB, reported sensitivity 99% and specificity 100%) is used as a serologic marker of exposure to Taenia solium in pigs. However, only a limited ...
Spontaneously Arrested Transmission of Cysticercosis in a Highly Endemic Village with a Very Low Migration Rate

Del Brutto, Oscar H.; O'Neal, Seth E.; Dorny, Pierre; García Lescano, Héctor Hugo (American Society of Tropical Medicine and Hygiene, 2018)

Taenia solium cysticercosis is difficult to eliminate without interventions or societal development. Atahualpa is a rural Ecuadorian village with documented low migration rate, where domestic pig raising is common and human ...
Successful Antiparasitic Treatment for Cysticercosis is Associated with a Fast and Marked Reduction of Circulating Antigen Levels in a Naturally Infected Pig Model

Gonzalez Zariquiey, Armando Emiliano; Bustos Palomino, Javier Arturo; García Lescano, Héctor Hugo; Rodriguez, Silvia; Zimic-Peralta, Mirko Juan; Castillo Berrios, Yesenia; Praet, Nicolas; Gabriel, Sarah; Gilman, Robert Hugh; Dorny, Pierre (American Society of Tropical Medicine and Hygiene, 2015)

Taenia solium cysticercosis is a common parasitic infection of humans and pigs. We evaluated the posttreatment evolution of circulating parasite-specific antigen titers in 693 consecutive blood samples from 50 naturally ...

Listar por autor "Dorny, Pierre"

Listar por autor "Dorny, Pierre"

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