Listar por autor "Eisenach, Kathleen"

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  • Increased Doses Lead to Higher Drug Exposures of Levofloxacin for Treatment of Tuberculosis 
    Peloquin, Charles A.; Phillips, Patrick P. J.; Mitnick, Carole D.; Eisenach, Kathleen; Patientia, Ramonde F.; Lecca, Leonid; Gotuzzo Herencia, José Eduardo; Gandhi, Neel R.; Butler, Donna; Diacon, Andreas H.; Martel, Bruno; Santillan, Juan; Hunt, Kathleen Robergeau; Vargas, Dante; von Groote-Bidlingmaier, Florian; Seas Ramos, Carlos Rafael; Dianis, Nancy; Moreno-Martinez, Antonio; Kaur, Pawandeep; Horsburgh, C. Robert (American Society for Microbiology, 2018)
    Patients with multidrug-resistant tuberculosis in Peru and South Africa were randomized to a weight-banded nominal dose of 11, 14, 17, or 20 mg/kg/day levofloxacin (minimum, 750 mg) in combination with other second-line ...
  • Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages 
    Stucki, David; Brites, Daniela; Jeljeli, Leila; Coscolla, Mireia; Liu, Qingyun; Trauner, Andrej; Fenner, Lukas; Rutaihwa, Liliana; Borrell, Sonia; Luo, Tao; Gao, Qian; Kato-Maeda, Midori; Ballif, Marie; Egger, Matthias; Macedo, Rita; Mardassi, Helmi; Moreno, Milagros; Tudo-Vilanova, Griselda; Fyfe, Janet; Globan, Maria; Thomas, Jackson; Jamieson, Frances; Guthrie, Jennifer-L.; Asante-Poku, Adwoa; Yeboah-Manu, Dorothy; Wampande, Eddie; Ssengooba, Willy; Joloba, Moses; Henry-Boom, W.; Basu, Indira; Bower, James; Saraiva, Margarida; Vaconcellos, Sidra-E. G.; Suffys, Philip; Koch, Anastasia; Wilkinson, Robert; Gail-Bekker, Linda; Malla, Bijaya; Ley, Serej-D.; Beck, Hans-Peter; de-Jong, Bouke-C.; Toit, Kadri; Sanchez-Padilla, Elisabeth; Bonnet, Maryline; Gil-Brusola, Ana; Frank, Matthias; Penlap-Beng, Veronique-N.; Eisenach, Kathleen; Alani, Issam; Wangui-Ndung'u, Perpetual; Revathi, Gunturu; Gehre, Florian; Akter, Suriya; Ntoumi, Francine; Stewart-Isherwood, Lynsey; Ntinginya, Nyanda-E.; Rachow, Andrea; Hoelscher, Michael; Cirillo, Daniela-Maria; Skenders, Girts; Hoffner, Sven; Bakonyte, Daiva; Stakenas, Petras; Diel, Roland; Crudu, Valeriu; Moldovan, Olga; Al-Hajoj, Sahal; Otero Vegas, Larissa; Barletta, Francesca; Jane-Carter, E.; Diero, Lameck; Supply, Philip; Comas, Inaki; Niemann, Stefan; Gagneux, Sebastien (Springer Nature, 2016)
    Generalist and specialist species differ in the breadth of their ecological niches. Little is known about the niche width of obligate human pathogens. Here we analyzed a global collection of Mycobacterium tuberculosis ...
  • An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial 
    Bouton, Tara C.; Phillips, Patrick P. J.; Mitnick, Carole D.; Peloquin, Charles A.; Eisenach, Kathleen; Patientia, Ramonde F.; Lecca, Leonid; Gotuzzo Herencia, José Eduardo; Gandhi, Neel R.; Butler, Donna; Diacon, Andreas H.; Martel, Bruno; Santillan, Juan; Hunt, Kathleen Robergeau; Vargas, Dante; von Groote-Bidlingmaier, Florian; Seas Ramos, Carlos Rafael; Dianis, Nancy; Moreno-Martinez, Antonio; Horsburgh, C. Robert (BioMed Central, 2017)
    BACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the ...

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