Listar por autor "Gabler, Fernando"

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  • ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in chileans 
    Boekstegers, Felix; Marcelain, Katherine; Barahona Ponce, Carol; Baez Benavides, Pablo F.; Müller, Bettina; de Toro, Gonzalo; Retamales, Javier; Barajas, Olga; Ahumada, Monica; Morales, Erik; Rojas, Armando; Sanhueza, Verónica; Loader, Denisse; Rivera, María Teresa; Gutiérrez, Lorena; Bernal, Giuliano; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Bertrán, Maria Enriqueta; Gabler, Fernando; Spencer, Loreto; Olloquequi, Jordi; González Silos, Rosa; Fischer, Christine; Scherer, Dominique; Jenab, Mazda; Aleksandrova, Krasimira; Katzke, Verena; Weiderpass, Elisabete; Moradi, Tahereh; Fischer, Krista; Bossers, Willem; Brenner, Hermann; Hveem, Kristian; Eklund, Niina; Völker, Uwe; Waldenberger, Melanie; Fuentes Guajardo, Macarena; Gonzalez-Jose, Rolando; Bedoya, Gabriel; Bortolini, Maria C.; Canizales, Samuel; Gallo López-Aliaga, Carla Maria; Ruiz Linares, Andres; Rothhammer, Francisco; Lorenzo Bermejo, Justo (Elsevier, 2020)
    BACKGROUND: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. ...
  • Development and internal validation of a multifactorial risk prediction model for gallbladder cancer in a high-incidence country 
    Boekstegers, Felix; Scherer, Dominique; Barahona Ponce, Carol; Marcelain, Katherine; Gárate-Calderón, Valentina; Waldenberger, Melanie; Morales, Erik; Rojas, Armando; Munoz, César; Retamales, Javier; de Toro, Gonzalo; Barajas, Olga; Rivera, María Teresa; Cortés, Analía; Loader, Denisse; Saavedra, Javiera; Gutiérrez, Lorena; Ortega, Alejandro; Bertrán, Maria Enriqueta; Bartolotti, Leonardo; Gabler, Fernando; Campos, Mónica; Alvarado, Juan; Moisán, Fabricio; Spencer, Loreto; Nervi, Bruno; Carvajal-Hausdorf, Daniel; Losada, Héctor; Almau, Mauricio; Fernández, Plinio; Olloquequi, Jordi; Fuentes-Guajardo, Macarena; Gonzalez-Jose, Rolando; Bortolini, Maria Cátira; Acuña-Alonzo, Victor; Gallo, Carla; Linares, Andres Ruiz; Rothhammer, Francisco; Lorenzo Bermejo, Justo (Wiley, 2023)
    Since 2006, Chile has been implementing a gallbladder cancer (GBC) prevention program based on prophylactic cholecystectomy for gallstone patients aged 35 to 49 years. The effectiveness of this prevention program has not ...
  • Gallbladder Cancer Risk and Indigenous South American Mapuche Ancestry: Instrumental Variable Analysis Using Ancestry-Informative Markers 
    Zollner, Linda; Boekstegers, Felix; Barahona Ponce, Carol; Scherer, Dominique; Marcelain, Katherine; Gárate-Calderón, Valentina; Waldenberger, Melanie; Morales, Erik; Rojas, Armando; Munoz, César; Retamales, Javier; De Toro, Gonzalo; Kortmann, Allan Vera; Barajas, Olga; Rivera, María Teresa; Cortés, Analía; Loader, Denisse; Saavedra, Javiera; Gutiérrez, Lorena; Ortega, Alejandro; Bertrán, Maria Enriqueta; Bartolotti, Leonardo; Gabler, Fernando; Campos, Mónica; Alvarado, Juan; Moisán, Fabricio; Spencer, Loreto; Nervi, Bruno; Carvajal, Daniel; Losada, Héctor; Almau, Mauricio; Fernández, Plinio; Olloquequi, Jordi; Carter, Alice R.; Miquel Poblete, Juan Francisco; Bustos, Bernabe Ignacio; Fuentes Guajardo, Macarena; Gonzalez-Jose, Rolando; Bortolini, Maria Cátira; Acuña-Alonzo, Victor; Gallo López-Aliaga, Carla Maria; Ruiz Linares, Andres; Rothhammer, Francisco; Lorenzo Bermejo, Justo (MDPI, 2023)
    A strong association between the proportion of indigenous South American Mapuche ancestry and the risk of gallbladder cancer (GBC) has been reported in observational studies. Chileans show the highest incidence of GBC ...
  • Gallstones, Body Mass Index, C-Reactive Protein, and Gallbladder Cancer: Mendelian Randomization Analysis of Chilean and European Genotype Data 
    Barahona Ponce, Carol; Scherer, Dominique; Brinster, Regina; Boekstegers, Felix; Marcelain, Katherine; Gárate-Calderón, Valentina; Müller, Bettina; de Toro, Gonzalo; Retamales, Javier; Barajas, Olga; Ahumada, Monica; Morales, Erik; Rojas, Armando; Sanhueza, Verónica; Loader, Denisse; Rivera, María Teresa; Gutiérrez, Lorena; Bernal, Giuliano; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Bertrán, Maria Enriqueta; Gabler, Fernando; Spencer, Loreto; Olloquequi, Jordi; Fischer, Christine; Jenab, Mazda; Aleksandrova, Krasimira; Katzke, Verena; Weiderpass, Elisabete; Bonet, Catalina; Moradi, Tahereh; Fischer, Krista; Bossers, Willem; Brenner, Hermann; Hveem, Kristian; Eklund, Niina; Völker, Uwe; Waldenberger, Melanie; Fuentes Guajardo, Macarena; Gonzalez-Jose, Rolando; Bedoya, Gabriel; Bortolini, Maria C.; Canizales-Quinteros, Samuel; Gallo López-Aliaga, Carla Maria; Ruiz-Linares, Andres; Rothhammer, Francisco; Lorenzo Bermejo, Justo (Wiley, 2021)
    BACKGROUND AND AIMS: Gallbladder cancer (GBC) is a neglected disease with substantial geographical variability: Chile shows the highest incidence worldwide, while GBC is relatively rare in Europe. Here, we investigate the ...
  • Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression 
    Blandino, Alice; Scherer, Dominique; Rounge, Trine B.; Umu, Sinan U.; Boekstegers, Felix; Barahona Ponce, Carol; Marcelain, Katherine; Gárate-Calderón, Valentina; Waldenberger, Melanie; Morales, Erik; Rojas, Armando; Munoz, César; Retamales, Javier; de Toro, Gonzalo; Barajas, Olga; Rivera, Maria Teresa; Cortés, Analía; Loader, Denisse; Saavedra, Javiera; Gutiérrez, Lorena; Ortega, Alejandro; Bertrán, Maria Enriqueta; Gabler, Fernando; Campos, Mónica; Alvarado, Juan; Moisán, Fabrizio; Spencer, Loreto; Nervi, Bruno; Carvajal-Hausdorf, Daniel E.; Losada, Héctor; Almau, Mauricio; Fernández, Plinio; Gallegos, Iván; Olloquequi, Jordi; Fuentes-Guajardo, Macarena; Gonzalez-Jose, Rolando; Bortolini, Maria Cátira; Gallo López-Aliaga, Carla Maria; Ruiz Linares, Andrés; Rothhammer, Francisco; Bermejo, Justo Lorenzo (MDPI, 2022)
    Long noncoding RNAs (lncRNAs) play key roles in cell processes and are good candi-dates for cancer risk prediction. Few studies have investigated the association between individual genotypes and lncRNA expression. Here we ...

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