Listar por autor "O'Connor, Timothy D."

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  • Scliar, Marilia O.; Sant'Anna, Hanaisa P.; Santolalla Robles, Meddly Leslye; Leal, Thiago P.; Araujo, Nathalia M.; Alvim, Isabela; Borda, Victor; Magalhaes, Wagner C. S.; Gouveia, Mateus H.; Lyra, Ricardo; Machado, Moara; Michelin, Lucas; Rodrigues, Maira R.; Araujo, Gilderlanio S.; Kehdy, Fernanda S. G.; Zolini, Camila; Peixoto, Sergio V.; Luizon, Marcelo R.; Lobo, Francisco; Naslavsky, Michel S.; Yamamoto, Guilherme L.; Duarte, Yeda A. O.; Hansen, Matthew E. B.; Norris, Shane A.; Gilman, Robert Hugh; Guio, Heinner; Hsing, Ann W.; Mbulaiteye, Sam M.; Mensah, James; Dutil, Julie; Yeager, Meredith; Yeboah, Edward; Tishkoff, Sarah A.; Choudhury, Ananyo; Ramsay, Michele; Passos-Bueno, Maria Rita; Zatz, Mayana; O'Connor, Timothy D.; Pereira, Alexandre C.; Barreto, Mauricio L.; Lima-Costa, Maria Fernanda; Horta, Bernardo L.; Tarazona-Santos, Eduardo (Springer, 2021)
    Background/objectives: Admixed populations are a resource to study the global genetic architecture of complex phenotypes, which is critical, considering that non-European populations are severely underrepresented in genomic ...
  • Loesch, Douglas P.; Horimoto, Andrea R. V. R.; Heilbron, Karl; Sarihan, Elif I.; Inca-Martinez, Miguel; Mason, Emily; Cornejo-Olivas, Mario; Torres, Luis; Mazzetti, Pilar; Cosentino, Carlos; Sarapura-Castro, Elison; Rivera-Valdivia, Andrea; Medina, Angel C.; Dieguez, Elena; Raggio, Victor; Lescano, Andrés; Tumas, Vitor; Borges, Vanderci; Ferraz, Henrique B.; Rieder, Carlos R.; Schumacher-Schuh, Artur; Santos-Lobato, Bruno L.; Velez-Pardo, Carlos; Jimenez-Del-Rio, Marlene; Lopera, Francisco; Moreno, Sonia; Chana-Cuevas, Pedro; Fernandez, William; Arboleda, Gonzalo; Arboleda, Humberto; Arboleda-Bustos, Carlos E.; Yearout, Dora; Zabetian, Cyrus P.; Cannon, Paul; Thornton, Timothy A.; O'Connor, Timothy D.; Mata, Ignacio F.; Latin Amer Res Consortium Genetics (Wiley, 2021)
    Objective This work was undertaken in order to identify Parkinson's disease (PD) risk variants in a Latino cohort, to describe the overlap in the genetic architecture of PD in Latinos compared to European-ancestry subjects, ...
  • Loesch, Douglas P.; Horimoto, Andrea R. V. R.; Sarihan, Elif Irem; Inca-Martinez, Miguel; Mason, Emily; Cornejo-Olivas, Mario; Torres, Luis; Mazzetti, Pilar; Cosentino, Carlos; Sarapura-Castro, Elison; Rivera-Valdivia, Andrea; Medina, Angel C.; Dieguez, Elena; Raggio, Victor; Lescano, Andrés; Tumas, Vitor; Borges, Vanderci; Ferraz, Henrique B.; Rieder, Carlos R.; Schumacher-Schuh, Artur; Santos-Lobato, Bruno L.; Velez-Pardo, Carlos; Jimenez-Del-Rio, Marlene; Lopera, Francisco; Moreno, Sonia; Chana-Cuevas, Pedro; Fernandez, William; Arboleda, Gonzalo; Arboleda, Humberto; Arboleda-Bustos, Carlos E.; Yearout, Dora; Zabetian, Cyrus P; Thornton, Timothy A.; Mata, Ignacio F.; O'Connor, Timothy D.; International Parkinson Disease Genomics Consortium (IPDGC); Latin American Research Consortium on the Genetics of Parkinson's Disease (LARGE-PD) (Elsevier, 2022)
    Background: Large-scale Parkinson's disease (PD) genome-wide association studies (GWAS) have, until recently, only been conducted on subjects with European-ancestry. Consequently, polygenic risk scores (PRS) constructed ...
  • Moreira, Rennan Garcias; Saraiva-Duarte, Julia Maria; Pereira, Alexandre Costa; Sosa-Macias, Martha; Galaviz-Hernandez, Carlos; Santolalla Robles, Meddly Leslye; Magalhaes, Wagner C. S.; Zolini, Camila; Leal, Thiago Peixoto; Balazs, Zsolt; Llerena, Adrian; Gilman, Robert Hugh; Mill, Jose Geraldo; Borda, Victor; Guio, Heinner; O'Connor, Timothy D.; Tarazona-Santos, Eduardo; Rodrigues-Soares, Fernanda (Wiley, 2022)
    PDE4B (phosphodiesterase-4B) has an important role in cancer and in pharmacology of some disorders, such as inflammatory diseases. Remarkably in Native Americans, PDE4B variants are associated with acute lymphoblastic ...

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