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Browsing by Author "O'Neal, Seth E."

Browsing by Author "O'Neal, Seth E."

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  • García, Héctor H.; González, Armando E.; O'Neal, Seth E.; Gilman, Robert H. (Instituto Nacional de Salud, 2018)
    Neurocysticercosis is the infection of the nervous system by the larvae (cysticerci) of the pork tapeworm Taenia solium. Neurocysticercosis is the major cause of acquired epilepsy worldwide and as such, it represents a ...
  • Flecker, Robert H.; Pray, Ian W.; Santivanez, Saul J.; Ayvar, Viterbo; Gamboa, Ricardo; Muro, Claudio; Moyano, Luz Maria; Benavides, Victor; Garcia, Hector H.; O'Neal, Seth E. (PLoS, 2017)
    BACKGROUND: Taenia solium inflicts substantial neurologic disease and economic losses on rural communities in many developing nations. "Ring-strategy" is a control intervention that targets treatment of humans and pigs ...
  • Beam, Michelle; Spencer, Angela; Fernandez, Lauralee; Atto, Ruth; Muro, Claudio; Vilchez, Percy; Gamboa, Ricardo; Olaya, Sandra; Ayvar, Viterbo; Gonzalez, Armando E.; Garcia, Hector H.; O'Neal, Seth E.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2018)
    Infection of the brain with Taenia solium larvae (neurocysticercosis) is a leading cause of preventable epilepsy worldwide. Effective and sustainable strategies to control parasite transmission in rural endemic communities ...
  • Garcia, Hector H.; Gonzalez, Armando E.; Tsang, Victor C. W.; O'Neal, Seth E.; Llanos-Zavalaga, Fernando; Gonzalvez, Guillermo; Romero, Jaime; Rodriguez, Silvia; Moyano, Luz M.; Ayvar, Viterbo; Diaz, Andre; Hightower, Allen; Craig, Philip S.; Lightowlers, Marshall W.; Gauci, Charles G.; Leontsini, Elli; Gilman, Robert H. (Massachusetts Medical Society, 2016)
    BACKGROUND: Taeniasis and cysticercosis are major causes of seizures and epilepsy. Infection by the causative parasite Taenia solium requires transmission between humans and pigs. The disease is considered to be eradicable, ...
  • Garcia, Hector H.; O'Neal, Seth E.; Gilman, Robert H. (Massachusetts Medical Society, 2016)
    Garcia et al. (June 16 issue) conclude that the transmission of taeniasis and cysticercosis was interrupted in a region in which these diseases are endemic owing to mass drug administration in humans and pigs. We are not ...
  • Fernandez, Lauralee; Gamboa, Ricardo; Vilchez, Percy; Pray, Ian; Beam, Michelle; Garvey, Brian; Spencer, Angela; Atto, Ruth; Muro, Claudio; Moyano, Luz Maria; Garcia, Hector H.; O'Neal, Seth E.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2019)
    Reintroduction of Taenia solium into a region in Peru where it had been eliminated prompted evaluation of the possibility of reintroduction from an urban reservoir of taeniasis. In a cross-sectional study of an adjacent ...
  • Gomez-Puerta, Lucho; Vargas-Calla, Ana; Castillo, Yesenia; Lopez-Urbina, Maria Teresa; Dorny, Pierre; Garcia, Hector H.; Gonzalez, Armando E.; O'Neal, Seth E. (Springer, 2019)
    BACKGROUND: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to ...
  • Lee, Chan; Noh, John; O'Neal, Seth E.; Gonzalez, Armando E.; Garcia, Hector H.; Handali, Sukwan (PLoS, 2019)
    We developed a novel and portable fluorescent sensor that integrates a lateral flow assay with a quantum dot (Qdots) label and a mobile phone reader for detection of specific antibodies in human serum. We evaluated the ...
  • Bustos, Javier A.; Arroyo, Gianfranco; Gilman, Robert H.; Soto-Becerra, Percy; Gonzales, Isidro; Saavedra, Herbert; Pretell, E. Javier; Nash, Theodore E.; O'Neal, Seth E.; Del Brutto, Oscar H.; Gonzalez, Armando E.; Garcia, Hector H.; Cysticercosis Working Group in Peru (Oxford University Press, 2020)
    BACKGROUND: Neurocysticercosis (NCC) is a major cause of acquired epilepsy in most of the world. Larval cysts in the human brain eventually resolve and either disappear or leave a calcified scar that is associated with ...
  • Moyano, Luz M.; O'Neal, Seth E.; Ayvar, Viterbo; Gonzalvez, Guillermo; Gamboa, Ricardo; Vilchez, Percy; Rodriguez, Silvia; Reistetter, Joe; Tsang, Victor C. W.; Gilman, Robert H.; Gonzalez, Armando E.; Garcia, Hector H. (PLoS, 2016)
    BACKGROUND: Neurocysticercosis is a common helminthic infection of the central nervous system and an important cause of adult-onset epilepsy in endemic countries. However, few studies have examined associations between ...
  • Garcia, Hector H.; O'Neal, Seth E.; Noh, John; Handali, Sukwan; Cysticercosis Working Group in Peru (American Society for Microbiology, 2018)
    Neurocysticercosis accounts for approximately 30% of all epilepsy cases in most developing countries. The immunodiagnosis of cysticercosis is complex and strongly influenced by the course of infection, the disease burden, ...
  • Garvey, Brian T.; Moyano, Luz M.; Ayvar, Viterbo; Rodriguez, Silvia; Gilman, Robert H.; Gonzalez, Armando E.; Garcia, Hector H.; O'Neal, Seth E.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2018)
    Neurocysticercosis causes substantial neurologic morbidity in endemic regions around the world. In this cross-sectional study, we describe the frequency of neurocysticercosis among a presumed high-risk group of people in ...
  • Muro, Claudio; Gomez-Puerta, Luis A.; Flecker, Robert H.; Gamboa, Ricardo; Barreto, Percy Vilchez; Dorny, Pierre; Tsang, Victor C. W.; Gilman, Robert H.; Gonzalez, Armando E.; Garcia, Hector H.; O'Neal, Seth E.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2017)
    The lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB, reported sensitivity 99% and specificity 100%) is used as a serologic marker of exposure to Taenia solium in pigs. However, only a limited ...
  • Vilchez Barreto, Percy M.; Gamboa, Ricardo; Santivañez, Saul; O'Neal, Seth E.; Muro, Claudio; Lescano, Andrés G.; Moyano, Luz-Maria; Gonzálvez, Guillermo; García, Hector H.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2017)
    Hymenolepis nana, the dwarf tapeworm, is a common intestinal infection of children worldwide. We evaluated infection and risk factor data that were previously collected from 14,761 children aged 2-15 years during a large-scale ...
  • O'Neal, Seth E.; Moyano, Luz M.; Ayvar, Viterbo; Rodriguez, Silvia; Gavidia, Cesar; Wilkins, Patricia P.; Gilman, Robert H.; Garcia, Hector H.; Gonzalez, Armando E. (PLoS, 2014)
    BACKGROUND: Taenia solium is a major cause of preventable epilepsy in developing nations. Screening and treatment of human intestinal stage infection (taeniasis) within high-risk foci may reduce transmission and prevent ...
  • Pray, Ian W.; Muro, Claudio; Gamboa, Ricardo; Vilchez, Percy; Wakeland, Wayne; Pan, William; Lambert, William E.; Garcia, Hector H.; O'Neal, Seth E. (Springer, 2019)
    BACKGROUND: Taenia solium (cysticercosis) is a parasitic cestode that is endemic in rural populations where open defecation is common and free-roaming pigs have access to human feces. The purpose of this study was to ...
  • Flores, Carlos Alonso; Jimenez, Juan; Gomez-Puerta, Luis A.; Palacios, Claudia; O'Neal, Seth E.; Muro, Claudio; Gonzalez, Armando E.; Gilman, Robert H.; Calderón, Maritza (Elsevier, 2021)
    Toxoplasma gondii is an important foodborne pathogen worldwide, with undercooked meat as the main source of human transmission. In this study, we determined the seroprevalence of T. gondii in free-range pigs from two ...
  • Pray, Ian W.; Ayvar, Viterbo; Gamboa, Ricardo; Muro, Claudio; Moyano, Luz M.; Benavides, Victor; Flecker, Robert H.; Garcia, Hector H.; O'Neal, Seth E. (PLoS, 2017)
    BACKGROUND: Taenia solium, a parasite that affects humans and pigs, is the leading cause of preventable epilepsy in the developing world. Geographic hotspots of pigs testing positive for serologic markers of T. solium ...
  • Del Brutto, Oscar H.; O'Neal, Seth E.; Dorny, Pierre; García, Héctor H. (American Society of Tropical Medicine and Hygiene, 2018)
    Taenia solium cysticercosis is difficult to eliminate without interventions or societal development. Atahualpa is a rural Ecuadorian village with documented low migration rate, where domestic pig raising is common and human ...
  • Beam, Michelle; Spencer, Angela G.; Atto, Ruth; Camizan, Roberto; Vilchez, Percy; Muro, Claudio; Gamboa, Ricardo; Pray, Ian; Garvey, Brian; Fernandez, Lauralee; Garcia, Hector H.; O'Neal, Seth E.; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2019)
    Cysticercosis, caused by Taenia solium, is a neglected disease that causes preventable epilepsy. We conducted an experiential learning workshop in northern Peru to educate community members on T. solium transmission and ...

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