Listar por autor "Rosas-Aguirre, Angel"

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Assessing malaria transmission in a low endemicity area of north-western Peru

Rosas-Aguirre, Angel; Llanos Cuentas, Elmer Alejandro; Speybroeck, Niko; Cook, Jackie; Contreras-Mancilla, Juan; Soto, Veronica; Gamboa Vilela, Dionicia Baziliza; Pozo, Edwar; Ponce, Oscar J.; Pereira, Mayne O.; Soares, Irene S.; Theisen, Michael; D'Alessandro, Umberto; Erhart, Annette (BioMed Central, 2013)

Background: Where malaria endemicity is low, control programmes need increasingly sensitive tools for monitoring malaria transmission intensity (MTI) and to better define health priorities. A cross-sectional survey was ...
Economic cost of uncomplicated Plasmodium vivax malaria case management in the Peruvian Amazon

Moreno-Gutierrez, Diamantina; Rosas-Aguirre, Angel; Llanos-Cuentas, Alejandro (Universidad Peruana Cayetano Heredia, 2019)

Peru is an upper-middle-income country, but a large part of the population is still unable to benefit from such economic growth, with poverty rates exceeding 40% in rural areas, mainly in the Andean and the Amazon Regions. ...
Economic costs analysis of uncomplicated malaria case management in the Peruvian Amazon

Moreno-Gutierrez, Diamantina; Rosas-Aguirre, Angel; Llanos Cuentas, Elmer Alejandro; Bilcke, Joke; Barboza, José Luis; Hayette, Marie-Pierre; Contreras-Mancilla, Juan; Aguirre, Kristhian; Gamboa Vilela, Dionicia Baziliza; Rodriguez, Hugo; Speybroeck, Niko; Beutels, Philippe (BioMed Central, 2020)

Background: Case management is one of the principal strategies for malaria control. This study aimed to estimate the economic costs of uncomplicated malaria case management and explore the influence of health-seeking ...
Effectiveness of a malaria surveillance strategy based on active case detection during high transmission season in the Peruvian Amazon

Moreno-Gutierrez, Diamantina; Llanos Cuentas, Elmer Alejandro; Luis Barboza, Jose; Contreras-Mancilla, Juan; Gamboa Vilela, Dionicia Baziliza; Rodriguez, Hugo; Carrasco Escobar, Gabriel; Boreux, Raphael; Hayette, Marie-Pierre; Beutels, Philippe; Speybroeck, Niko; Rosas-Aguirre, Angel (MDPI, 2018)

Background: Faced with the resurgence of malaria, malaria surveillance in the Peruvian Amazon incorporated consecutive active case detection (ACD) interventions using light microscopy (LM) as reactive measure in communities ...
Epidemiology of Plasmodium vivax Malaria in Peru

Rosas-Aguirre, Angel; Gamboa Vilela, Dionicia Baziliza; Manrique Valverde, Paulo Cesar; Conn, Jan-E.; Moreno, Marta; Lescano Guevara, Andres Guillermo; Sanchez, Juan-F.; Rodriguez, Hugo; Silva, Hermann; Llanos Cuentas, Elmer Alejandro; Vinetz, Joseph Michael (American Society of Tropical Medicine and Hygiene, 2016)

Malaria in Peru, dominated by Plasmodium vivax, remains a public health problem. The 1990s saw newly epidemic malaria emerge, primarily in the Loreto Department in the Amazon region, including areas near to Iquitos, the ...
Hotspots of Malaria Transmission in the Peruvian Amazon: Rapid Assessment through a Parasitological and Serological Survey

Rosas-Aguirre, Angel; Speybroeck, Niko; Llanos Cuentas, Elmer Alejandro; Rosanas-Urgell, Anna; Carrasco Escobar, Gabriel; Rodriguez, Hugo; Gamboa Vilela, Dionicia Baziliza; Contreras-Mancilla, Juan; Alava, Freddy; Soares, Irene S.; Remarque, Edmond; D Alessandro, Umberto; Erhart, Annette (Public Library of Science, 2015)

BACKGROUND: With low and markedly seasonal malaria transmission, increasingly sensitive tools for better stratifying the risk of infection and targeting control interventions are needed. A cross-sectional survey to ...
Household level spatio-temporal analysis of Plasmodium falciparum and Plasmodium vivax malaria in Ethiopia

Seyoum, Dinberu; Yewhalaw, Delenasaw; Duchateau, Luc; Brandt, Patrick; Rosas-Aguirre, Angel; Speybroeck, Niko (BioMed Central, 2017)

Background: The global decline of malaria burden and goals for elimination has led to an increased interest in the fine-scale epidemiology of malaria. Micro-geographic heterogeneity of malaria infection could have implications ...
Human-mobility-related transmission of new parasite genetic clusters in Mazan basin in the Peruvian Amazon

Manrique, Paulo; Nolasco, Oscar; Ramirez, Roberson; Miranda-Alban, J.; Carrasco-Escobar, Gabriel; Contreras-Mancilla Juan Jose; Rodriguez, Hugo; Speybroeck, Niko; Rosas-Aguirre, Angel; Llanos-Cuentas, Alejandro; Escalante, Ananias A.; Gamboa, Dionisia (Universidad Peruana Cayetano Heredia, 2019)

Plasmodium vivax is the main cause of malaria in the Peruvian Amazon and Mazan is considered one of its districts with high risk of malaria transmission. In this site, previous studies has described P. vivax transmission ...
Identification of different malaria patterns due to Plasmodium falciparum and Plasmodium vivax in Ethiopian children: a prospective cohort study

Seyoum, Dinberu; Kifle, Yehenew-Getachew; Rondeau, Virginie; Yewhalaw, Delenasaw; Duchateau, Luc; Rosas-Aguirre, Angel; Speybroeck, Niko (BioMed Central, 2016)

BACKGROUND: The identification of epidemiological pattern of infection with Plasmodium falciparum and Plasmodium vivax in malaria-endemic area, where multiple episodes are common, is important for intervention programmes. ...
Integrating Parasitological and Entomological Observations to Understand Malaria Transmission in Riverine Villages in the Peruvian Amazon.

Rosas-Aguirre, Angel; Moreno, Marta; Moreno-Gutierrez, Diamantina; Llanos Cuentas, Elmer Alejandro; Saavedra Romero, Marlon Pierino; Contreras-Mancilla, Juan; Barboza, Jose; Alava, Freddy; Aguirre, Kristhian; Carrasco Escobar, Gabriel; Prussing, Catharine; Vinetz, Joseph Michael; Conn, Jan E.; Speybroeck, Niko; Gamboa Vilela, Dionicia Baziliza (Oxford University Press, 2021)

BACKGROUND: Remote rural riverine villages account for most of the reported malaria cases in the Peruvian Amazon. As transmission decreases due to intensive standard control efforts, malaria strategies in these villages ...
Long-Lasting Insecticide Net Ownership, Access and Use in Southwest Ethiopia: A Community-Based Cross-Sectional Study

Seyoum, Dinberu; Speybroeck, Niko; Duchateau, Luc; Brandt, Patrick; Rosas-Aguirre, Angel (MDPI, 2017)

Introduction:A large proportion of the Ethiopian population (approximately 68%) lives in malaria risk areas. Millions of long-lasting insecticide treated nets (LLINs) have been distributed as part of the malaria prevention ...
Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon

Serra-Casas, Elisa; Manrique Valverde, Paulo Cesar; Ding, Xavier C.; Carrasco Escobar, Gabriel; Alava, Freddy; Gave, Anthony; Rodriguez, Hugo; Contreras-Mancilla, Juan; Rosas-Aguirre, Angel; Speybroeck, Niko; González, Iveth J.; Rosanas-Urgell, Anna; Gamboa Vilela, Dionicia Baziliza (Public Library of Science, 2017)

BACKGROUND: Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the ...
Micro-epidemiology and spatial heterogeneity of P. vivax parasitaemia in riverine communities of the Peruvian Amazon: A multilevel analysis

Carrasco Escobar, Gabriel; Gamboa Vilela, Dionicia Baziliza; Castro, Marcia C.; Bangdiwala, Shrikant I.; Rodriguez, Hugo; Contreras-Mancilla, Juan; Alava, Freddy; Speybroeck, Niko; Lescano Guevara, Andres Guillermo; Vinetz, Joseph Michael; Rosas-Aguirre, Angel; Llanos Cuentas, Elmer Alejandro (Springer Nature, 2017)

Malaria has steadily increased in the Peruvian Amazon over the last five years. This study aimed to determine the parasite prevalence and micro-geographical heterogeneity of Plasmodium vivax parasitaemia in communities of ...
Micro-heterogeneity of malaria transmission in the Peruvian Amazon: a baseline assessment underlying a population-based cohort study

Rosas-Aguirre, Angel; Guzman Guzman, Mitchel Anthony; Gamboa Vilela, Dionicia Baziliza; Chuquiyauri, Raul; Ramirez, Roberson; Manrique Valverde, Paulo Cesar; Carrasco Escobar, Gabriel; Puemape Cárdenas, Carmen Luz; Llanos Cuentas, Elmer Alejandro; Vinetz, Joseph Michael (BioMed Central, 2017)

BACKGROUND: Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and ...
Microsatellite analysis reveals connectivity among geographically distant transmission zones of Plasmodium vivax in the Peruvian Amazon: A critical barrier to regional malaria elimination

Manrique Valverde, Paulo Cesar; Miranda-Alban, Julio; Alarcon-Baldeon, Jhonatan; Ramirez, Roberson; Carrasco Escobar, Gabriel; Herrera, Henry; Guzman Guzman, Mitchel Anthony; Rosas-Aguirre, Angel; Llanos Cuentas, Elmer Alejandro; Vinetz, Joseph Michael; Escalante, Ananias A.; Gamboa Vilela, Dionicia Baziliza (Public Library of Science, 2019)

Despite efforts made over decades by the Peruvian government to eliminate malaria, Plasmodium vivax remains a challenge for public health decision-makers in the country. The uneven distribution of its incidence, plus its ...
Modelling the potential of focal screening and treatment as elimination strategy for Plasmodium falciparum malaria in the Peruvian Amazon Region

Rosas-Aguirre, Angel; Erhart, Annette; Llanos Cuentas, Elmer Alejandro; Branch, Oralee; Berkvens, Dirk; Abatih, Emmanuel; Lambert, Philippe; Frasso, Gianluca; Rodriguez, Hugo; Gamboa Vilela, Dionicia Baziliza; Sihuincha, Moises; Rosanas-Urgell, Anna; D'Alessandro, Umberto; Speybroeck, Niko (BioMed Central, 2015)

BACKGROUND: Focal screening and treatment (FSAT) of malaria infections has recently been introduced in Peru to overcome the inherent limitations of passive case detection (PCD) and further decrease the malaria burden. ...
Plasmodium vivax malaria at households: spatial clustering and risk factors in a low endemicity urban area of the northwestern Peruvian coast

Rosas-Aguirre, Angel; Ponce, Oscar J.; Carrasco Escobar, Gabriel; Speybroeck, Niko; Contreras-Mancilla, Juan; Gamboa Vilela, Dionicia Baziliza; Pozo, Edwar; Herrera, Socrates; Llanos Cuentas, Elmer Alejandro (BioMed Central, 2015)

BACKGROUND: Peru has presented a decreasing malaria trend during the last decade, particularly in areas on northwestern coast; however, a limited number of cases continues to be reported yearly mainly in malaria hotspots. ...
Plasmodium vivax mono-infection as main cause of severe malaria in a co-endemic region for P. vivax and P. falciparum in the Peruvian Amazon

Moreno-Gutierrez, Diamantina; Casapía, Martin; Quino-Ascurra, Higinio; Celis-Salinas, J.; Quiroz-Morey, A.; Barbosa-Chichipe, José Luis; Llanos-Cuentas, Alejandro; Beutels, Philippe; Speybroeck, Niko; Rosas-Aguirre, Angel (Universidad Peruana Cayetano Heredia, 2019)

Loreto, covering 28% of Peru's territory with around one million inhabitants, is the department most affected by malaria. In 2017, it reported 53163 malaria cases (about 90% of total cases in the country), of which 75% and ...
Proyecto Serovivax (Elac2015/ T08-1061): Identificación a Escala Genómica de Microarreglos de Proteínas de Respuestas de Anticuerpos que Mejor Discriminan Entre Infecciones Recientes y Antiguas a Plasmodium vivax en la Amazonía Peruana

Rosas-Aguirre, Angel; Contreras-Mancilla, Juan; White, Michael; Severini, Cinzia; Silva-Soares, Irine; Percy, M.; Erhart, Annette; Gatto, Laurent; Mueller, Ivo; Llanos-Cuentas, Alejandro; Vinetz, Joseph; Speybroeck, Niko (Universidad Peruana Cayetano Heredia, 2019)

Plasmodium vivax es un desafío para la eliminación de la malaria. Esta especie cuenta con un estadío hepático latente (Hipnozoíto) que mantiene la transmisión de la enfermedad. El proyecto SEROVIVAX tiene como objetivo ...
Relative contribution of low-density and asymptomatic infections to Plasmodium vivax transmission in the Amazon: pooled analysis of individual participant data from population-based cross-sectional surveys

Ferreira, Marcelo U.; Corder, Rodrigo M.; Johansen, Igor C.; Kattenberg, Johanna H.; Moreno, Marta; Rosas-Aguirre, Angel; Ladeia-Andrade, Simone; Conn, Jan E.; Llanos Cuentas, Elmer Alejandro; Gamboa Vilela, Dionicia Baziliza; Rosanas-Urgell, Anna; Vinetz, Joseph Michael (Elsevier, 2022)

Background: Low-density and asymptomatic Plasmodium vivax infections remain largely undetected and untreated and may contribute significantly to malaria transmission in the Amazon. Methods: We analysed individual participant ...