Listar por autor "Vinetz, Joseph Michael"

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  • Acceptability of a herd immunity-focused, transmission-blocking malaria vaccine in malaria-endemic communities in the Peruvian Amazon: an exploratory study 
    White, Sara E.; Harvey, Steven A.; Meza, Graciela; Llanos Cuentas, Elmer Alejandro; Guzman Guzman, Mitchel Anthony; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael (BioMed Central, 2018)
    BACKGROUND: A transmission-blocking vaccine (TBV) to prevent malaria-infected humans from infecting mosquitoes has been increasingly considered as a tool for malaria control and elimination. This study tested the hypothesis ...
  • Amazonian malaria: Asymptomatic human reservoirs, diagnostic challenges, environmentally driven changes in mosquito vector populations, and the mandate for sustainable control strategies 
    da Silva-Nunes, M.; Moreno, M.; Conn, J.E.; Gamboa Vilela, Dionicia Baziliza; Abeles, S.; Vinetz, Joseph Michael; Ferreira, M.U. (Elsevier, 2012)
    Across the Americas and the Caribbean, nearly 561,000 slide-confirmed malaria infections were reported officially in 2008. The nine Amazonian countries accounted for 89% of these infections; Brazil and Peru alone contributed ...
  • Anti-Plasmodium falciparum invasion ligand antibodies in a low malaria transmission region, Loreto, Peru 
    Villasis Mayuri, Elizabeth Melisa; Lopez-Perez, M.; Torres Fajardo, Katherine Jessica; Gamboa Vilela, Dionicia Baziliza; Neyra, V.; Bendezu, J.; Tricoche, N.; Lobo, C.; Vinetz, Joseph Michael; Lustigman, S. (BioMed Central, 2012)
    Background: Erythrocyte invasion by Plasmodium falciparum is a complex process that involves two families; Erythrocyte Binding-Like (EBL) and the Reticulocyte Binding-Like (PfRh) proteins. Antibodies that inhibit merozoite ...
  • Anti–MSP-10 IgG indicates recent exposure to Plasmodium vivax infection in the Peruvian Amazon 
    Rosas-Aguirre, A.; Patra, K.P.; Calderón Sánchez, Maritza Mercedes; Torres Fajardo, Katherine Jessica; Gamboa Vilela, Dionicia Baziliza; Arocutipa, E.; Málaga, E.; Garro, K.; Fernández, C.; Trompeter, G.; Alnasser, Y.; Llanos Cuentas, Elmer Alejandro; Gilman, Robert Hugh; Vinetz, Joseph Michael (American Society for Clinical Investigation, 2020)
    BACKGROUND. Serological tools for the accurate detection of recent malaria exposure are needed to guide and monitor malaria control efforts. IgG responses against Plasmodium vivax and P. falciparum merozoite surface ...
  • Assessment of an automated capillary system for Plasmodium vivax microsatellite genotyping 
    Manrique Valverde, Paulo Cesar; Hoshi, Mari; Fasabi, Manuel; Nolasco, Oscar; Yori, Pablo; Calderón Sánchez, Maritza Mercedes; Gilman, Robert Hugh; Kosek, Margaret N.; Vinetz, Joseph Michael; Gamboa Vilela, Dionicia Baziliza (BioMed Central, 2015)
    BACKGROUND: Several platforms have been used to generate the primary data for microsatellite analysis of malaria parasite genotypes. Each has relative advantages but share a limitation of being time- and cost-intensive. A ...
  • Brucella melitensis T cell epitope recognition in humans with brucellosis in Peru 
    Cannella, Anthony P.; Arlehamn, Cecilia S.Lindestam; Sidney, John; Patra, Kallash P.; Torres Fajardo, Katherine Jessica; Tsolis, Renee M.; Liang, Li; Felgner, Philip L.; Saito, Mayuko; Gotuzzo Herencia, José Eduardo; Gilman, Robert Hugh; Sette, Alessandro; Vinetz, Joseph Michael (American Society for Microbiology, 2014)
    Brucella melitensis, one of the causative agents of human brucellosis, causes acute, chronic, and relapsing infection. While T cell immunity in brucellosis has been extensively studied in mice, no recognized human T cell ...
  • Changes in Genetic Diversity from Field to Laboratory During Colonization of Anopheles darlingi Root (Diptera: Culicidae) 
    Lainhart, William; Bickersmith, Sara A.; Moreno, Marta; Rios, Carlos Tong; Vinetz, Joseph Michael; Conn, Jan E. (American Society of Tropical Medicine and Hygiene, 2015)
    The process of colonizing any arthropod species, including vector mosquitoes, necessarily involves adaptation to laboratory conditions. The adaptation and evolution of colonized mosquito populations needs consideration ...
  • Characteristics of rural leptospirosis patients admitted to referral hospitals during the 2008 leptospirosis outbreak in Sri Lanka: implications for developing public health control measures 
    Agampodi, Suneth B.; Nugegoda, Dhanaseela B.; Thevanesam, Vasanthi; Vinetz, Joseph Michael (American Society of Tropical Medicine and Hygiene, 2015)
    To determine the exposure risk factors of highly endemic rural leptospirosis in tropical setting, we conducted a prospective, hospital-based case control study in Sri Lanka. A conceptual hierarchy of variables was used to ...
  • Characteristics of Travel-Related Severe Plasmodium vivax and Plasmodium falciparum Malaria in Individuals Hospitalized at a Tertiary Referral Center in Lima, Peru 
    Llanos-Chea, Fiorella; Martinez, Dalila; Rosas, Angel; Samalvides Cuba, Frine; Vinetz, Joseph Michael; Llanos Cuentas, Elmer Alejandro (American Society of Tropical Medicine and Hygiene, 2015)
    Severe Plasmodium falciparum malaria is uncommon in South America. Lima, Peru, while not endemic for malaria, is home to specialized centers for infectious diseases that admit and manage patients with severe malaria (SM), ...
  • Colorimetric Detection of Plasmodium vivax in Urine Using MSP10 Oligonucleotides and Gold Nanoparticles 
    Alnasser, Yossef; Ferradas, Cusi; Clark, Taryn; Calderón Sánchez, Maritza Mercedes; Gurbillon, Alejandro; Gamboa Vilela, Dionicia Baziliza; McKakpo, Uri S.; Quakyi, Isabella A.; Bosompem, Kwabena M.; Sullivan, David J.; Vinetz, Joseph Michael; Gilman, Robert Hugh (Public Library of Science, 2016)
    Plasmodium vivax is the most prevalent cause of human malaria in the world and can lead to severe disease with high potential for relapse. Its genetic and geographic diversities make it challenging to control. P. vivax is ...
  • Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes 
    Prajapati, Surendra Kumar; Borlon, Celine; Rovira-Vallbona, Eduard; Gruszczyk, Jakub; Menant, Sebastien; Tham, Wai-Hong; Kattenberg, Johanna Helena; Villasis Mayuri, Elizabeth Melisa; De Meulenaere, Katlijn; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael; Fujita, Ricardo; Xuan, Xa Nguyen; Urbano Ferreira, Marcelo; Nino, Carlos H.; Patarroyo, Manuel A.; Spanakos, Gregory; Kestens, Luc; Abbeele, Jan Van Den; Rosanas-Urgell, Anna (Springer Nature, 2019)
    Plasmodium vivax parasites preferentially invade reticulocyte cells in a multistep process that is still poorly understood. In this study, we used ex vivo invasion assays and population genetic analyses to investigate the ...
  • Continuous Supply of Plasmodium vivax Sporozoites from Colonized Anopheles darlingi in the Peruvian Amazon 
    Moreno, Marta; Tong-Rios, Carlos; Orjuela-Sanchez, Pamela; Carrasco Escobar, Gabriel; Campo, Brice; Gamboa Vilela, Dionicia Baziliza; Winzeler, Elizabeth A.; Vinetz, Joseph Michael (American Chemical Society, 2018)
    In vitro culture of Plasmodium vivax liver stages underlies key understandings of the fundamental biology of this parasite, particularly the latent, hyponozoite stage, toward drug and vaccine development. Here, we report ...
  • Decreasing proportion of Anopheles darlingi biting outdoors between long-lasting insecticidal net distributions in peri-Iquitos, Amazonian Peru 
    Prussing, C.; Moreno, M.; Saavedra Romero, Marlon Pierino; Bickersmith, S. A.; Gamboa Vilela, Dionicia Baziliza; Alava, F.; Schlichting, C. D.; Emerson, K. J.; Vinetz, Joseph Michael; Conn, J. E. (BioMed Central, 2018)
    In Loreto Department, Peru, a successful 2005–2010 malaria control programme (known as PAMAFRO) included massive distribution of long-lasting insecticidal nets (LLINs). Additional local distribution of LLINs occurred in ...
  • Developing Plasmodium vivax Resources for Liver Stage Study in the Peruvian Amazon Region 
    Orjuela-Sanchez, Pamela; Villa, Zaira Hellen; Moreno, Marta; Tong-Rios, Carlos; Meister, Stephan; LaMonte, Gregory M.; Campo, Brice; Vinetz, Joseph Michael; Winzeler, Elizabeth A. (American Chemical Society, 2018)
    To develop new drugs and vaccines for malaria elimination, it will be necessary to discover biological interventions, including small molecules that act against Plasmodium vivax exoerythrocytic forms. However, a robust in ...
  • Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children 
    Felgner, Jiin; Jain, Aarti; Nakajima, Rie; Liang, Li; Jasinskas, Algis; Gotuzzo Herencia, José Eduardo; Vinetz, Joseph Michael; Miyajima, Fabio; Pirmohamed, Munir; Hassan-Hanga, Fatimah; Umoru, Dominic; Jibir, Binta Wudil; Gambo, Safiya; Olateju, Kudirat; Felgner, Philip L.; Obaro, Stephen; Davies, D. Huw (Public Library of Science, 2017)
    Improved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ...
  • Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection 
    LaMonte, G.M.; Orjuela-Sanchez, P.; Calla Choque, Jaeson Santos; Wang, L.T.; Li, S.; Swann, J.; Cowell, A.N.; Zou, B.Y.; Abdel-Haleem Mohamed, A.M.; Villa Galarce, Z.H.; Moreno, M.; Tong Rios, C.; Vinetz, Joseph Michael; Lewis, N.; Winzeler, E.A. (Springer Nature, 2019)
    The exoerythrocytic stage of Plasmodium infection is a critical window for prophylactic intervention. Using genome-wide dual RNA sequencing of flow-sorted infected and uninfected hepatoma cells we show that the human mucosal ...
  • Ecology and larval population dynamics of the primary malaria vector Nyssorhynchus darlingi in a high transmission setting dominated by fish farming in western Amazonian Brazil 
    Rufalco-Moutinho, Paulo; Moura Kadri, Samir; Peres Alonso, Diego; Moreno, Marta; Carrasco Escobar, Gabriel; Prussing, Catharine; Gamboa Vilela, Dionicia Baziliza; Vinetz, Joseph Michael; Mureb Sallum, Maria Anice; Conn, Jan E.; Martins Ribolla, Paulo Eduardo (Public Library of Science, 2021)
    Vale do Rio Jurua in western Acre, Brazil, is a persistent malaria transmission hotspot partly due to fish farming development that was encouraged to improve local standards of living. Fish ponds can be productive breeding ...
  • Effect of out-of-village working activities on recent malaria exposure in the Peruvian Amazon using parametric g-formula 
    Carrasco Escobar, Gabriel; Rosado, J.; Nolasco, Oscar; White, M.T.; Mueller, I.; Castro, M.C.; Rodriguez-Ferruci, H.; Gamboa Vilela, Dionicia Baziliza; Llanos Cuentas, Elmer Alejandro; Vinetz, Joseph Michael; Benmarhnia, T. (Springer, 2022)
    In the Amazon Region of Peru, occupational activities are important drivers of human mobility and may increase the individual risk of being infected while contributing to increasing malaria community-level transmission. ...
  • Epidemiological characteristics of P. vivax asymptomatic infections in the Peruvian Amazon 
    Villasis Mayuri, Elizabeth Melisa; Garcia Castillo, Stefano S.; Guzman Guzman, Mitchel Anthony; Torres, Julian; Gomez, Joaquin; Garro, Katherine; Cordova, Ana Maria; Reategui, Carolina; Abanto, Caroline; Vinetz, Joseph Michael; Gamboa Vilela, Dionicia Baziliza; Torres Fajardo, Katherine Jessica (Frontiers Media, 2022)
    Introduction: Herein, we tested the hypothesis that Asymptomatic P. vivax (Pv) infected individuals (Asym) feature different epidemiological, clinical and biochemical characteristics, as well as hematological parameters, ...
  • Epidemiology of disappearing Plasmodium vivax malaria: a case study in rural Amazonia 
    Barbosa, Susana; Gozze, Amanda B.; Lima, Nathália F.; Batista, Camilla L.; Bastos, Melissa da Silva; Nicolete, Vanessa C.; Fontoura, Pablo S.; Gonçalves, Raquel M.; Viana, Susana Ariane S.; Menezes, Maria José; Scopel, Kézia Katiani G.; Cavasini, Carlos E.; Malafronte, Rosely dos Santos; da Silva-Nunes, Mônica; Vinetz, Joseph Michael; Castro, Márcia C.; Ferreira, Marcelo U. (Public Library of Science, 2014)
    Background: New frontier settlements across the Amazon Basin pose a major challenge for malaria elimination in Brazil. Here we describe the epidemiology of malaria during the early phases of occupation of farming settlements ...

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