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Systematic reviews supporting practice guideline recommendations lack protection against bias

Brito, Juan P.; Tsapas, Apostolos; Griebeler, Marcio L.; Wang, Zhen; Prutsky, Gabriela J.; Domecq, Juan Pablo; Murad, M.Hassan; Montori, Victor M. (Elsevier, 2013)

To evaluate the quality of systematic reviews (SRs) affecting clinical practice in endocrinology.