Listar por tema "Alzheimer Disease/enzymology/metabolism/therapy"

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Uncontrolled SFK-mediated protein trafficking in prion and Alzheimer's disease

Málaga Trillo, George Edward; Ochs, Katharina (Taylor and Francis, 2016)

Prions and Amyloid beta (Aβ) peptides induce synaptic damage via complex mechanisms that include the pathological alteration of intracellular signaling cascades. The host-encoded cellular prion protein (PrPC) acts as a ...