Browsing by Subject "Antigens, Protozoan/genetics/immunology"

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Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: impact on vaccine design for placental malaria

Bordbar, Bita; Tuikue Ndam, Nicaise; Renard, Emmanuelle; Jafari-Guemouri, Sayeh; Tavul, Livingstone; Jennison, Charlie; Gnidehou, Sedami; Tahar, Rachida; Gamboa Vilela, Dionicia Baziliza; Bendezu, Jorge; Menard, Didier; Barry, Alyssa E.; Deloron, Philippe; Sabbagh, Audrey (Elsevier, 2014)

In placental malaria (PM), sequestration of infected erythrocytes in the placenta is mediated by an interaction between VAR2CSA, a Plasmodium falciparum protein expressed on erythrocytes, and chondroitin sulfate A (CSA) ...
Genome-level determination of Plasmodium falciparum blood-stage targets of malarial clinical immunity in the Peruvian Amazon

Torres Fajardo, Katherine Jessica; Castrillon, Carlos E.; Moss, Eli L.; Saito, Mayuko; Tenorio, Roy; Molina, Douglas M.; Davies, Huw; Neafsey, Daniel E.; Felgner, Philip; Vinetz, Joseph Michael; Gamboa Vilela, Dionicia Baziliza (Oxford University Press, 2015)

BACKGROUND: Persons with blood-stage Plasmodium falciparum parasitemia in the absence of symptoms are considered to be clinically immune. We hypothesized that asymptomatic subjects with P. falciparum parasitemia would ...

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