Listar por tema "Bacterial Proteins/genetics/metabolism"

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What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

Fouts, Derrick-E.; Matthias, Michael-A.; Adhikarla, Haritha; Adler, Ben; Amorim-Santos, Luciane; Berg, Douglas-E.; Bulach, Dieter; Buschiazzo, Alejandro; Chang, Yung-Fu; Galloway, Renee-L.; Haake, David-A.; Haft, Daniel-H.; Hartskeerl, Rudy; Ko, Albert-I.; Levett, Paul-N.; Matsunaga, James; Mechaly, Ariel-E.; Monk, Jonathan-M.; Nascimento, Ana-L. T.; Nelson, Karen-E.; Palsson, Bernhard; Peacock, Sharon-J.; Picardeau, Mathieu; Ricaldi, Jessica-N.; Thaipandungpanit, Janjira; Wunder, Elsio-A. Jr; Yang, X. Frank; Zhang, Jun-Jie; Vinetz, Joseph Michael (Public Library of Science, 2016)

Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread, neglected and emerging zoonotic disease. While whole genome analysis of individual pathogenic, intermediately pathogenic and saprophytic ...
Whole Genome Shotgun Sequencing Shows Selection on Leptospira Regulatory Proteins During in vitro Culture Attenuation

Lehmann, Jason S.; Corey, Victoria C.; Ricaldi, Jessica N.; Vinetz, Joseph Michael; Winzeler, Elizabeth A.; Matthias, Michael A. (American Society of Tropical Medicine and Hygiene, 2016)

Leptospirosis is the most common zoonotic disease worldwide with an estimated 500,000 severe cases reported annually, and case fatality rates of 12-25%, due primarily to acute kidney and lung injuries. Despite its prevalence, ...

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