Listar por tema "Caucasian"

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  • Development of a panel of genome-wide ancestry informative markers to study admixture throughout the americas 
    Galanter, J.M.; Fernandez-Lopez, J.C.; Gignoux, C.R.; Barnholtz-Sloan, J.; Fernandez-Rozadilla, C.; Via, M.; Hidalgo-Miranda, A.; Contreras, A.V.; Figueroa, L.U.; Raska, P.; Jimenez-Sanchez, G.; Zolezzi, I.S.; Torres, M.; Ponte, C.R.; Ruiz, Y.; Salas, A.; Nguyen, E.; Eng, C.; Borjas, L.; Zabala, W.; Barreto, G.; González, F.R.; Ibarra, A.; Taboada, P.; Porras, L.; Moreno, F.; Bigham, A.; Gutierrez, G.; Brutsaert, T.; León-Velarde, Fabiola; Moore, L.G.; Vargas, E.; Cruz, M.; Escobedo, J.; Rodriguez-Santana, J.; Rodriguez-Cintrón, W.; Chapela, R.; Ford, J.G.; Bustamante, C.; Seminara, D.; Shriver, M.; Ziv, E.; Burchard, E.G.; Haile, R.; Parra, E.; Carracedo, A. (Public Library of Science, 2012)
    Most individuals throughout the Americas are admixed descendants of Native American, European, and African ancestors. Complex historical factors have resulted in varying proportions of ancestral contributions between ...
  • Geografía génica de Chile. Distribución regional de los aportes genéticos americanos, europeos y africanos 
    Fuentes, Macarena; Pulgar, Iván; Gallo López-Aliaga, Carla Maria; Bortolini, María-Cátira; Canizales-Quinteros, Samuel; Bedoya, Gabriel; González-José, Rolando; Ruiz-Linares, Andrés; Rothhammer, Francisco (Sociedad Médica de Santiago, 2014)
    Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
  • A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia 
    Adhikari, K.; Mendoza-Revilla, J.; Sohail, A.; Fuentes-Guajardo, M.; Lampert, J.; Chacón-Duque, J.C.; Hurtado, M.; Villegas, V.; Granja, V.; Acuña-Alonzo, V.; Jaramillo, C.; Arias, W.; Lozano, R.B.; Everardo, P.; Gómez-Valdés, J.; Villamil-Ramírez, H.; Silva de Cerqueira, C.C.; Hunemeier, T.; Ramallo, V.; Schuler-Faccini, L.; Salzano, F.M.; Gonzalez-José, R.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Bedoya, G.; Rothhammer, F.; Tobin, D.J.; Fumagalli, M.; Balding, D.; Ruiz-Linares, A. (Springer Nature, 2019)
    We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation ...
  • Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations 
    Kehdy, F.S.G.; Gouveia, M.H.; Machado, M.; Magalhães, W.C.S.; Horimoto, A.R.; Horta, B.L.; Moreira, R.G.; Leal, T.P.; Scliar, M.O.; Soares-Souza, G.B.; Rodrigues-Soares, F.; Araújo, G.S.; Zamudio, R.; Sant Anna, H.P.; Santos, H.C.; Duarte, N.E.; Fiaccone, R.L.; Figueiredo, C.A.; Silva, T.M.; Costa, G.N.O.; Beleza, S.; Berg, D.E.; Cabrera, L.; Debortoli, G.; Duarte, D.; Ghirotto, S.; Gilman, Robert Hugh; Gonçalves, V.F.; Marrero, A.R.; Muniz, Y.C.; Weissensteiner, H.; Yeager, M.; Rodrigues, L.C.; Barreto, M.L.; Lima-Costa, M.F.; Pereira, A.C.; Rodrigues, M.R.; Tarazona-Santos, E. (National Academy of Sciences, 2015)
    While South Americans are underrepresented in human genomic diversity studies, Brazil has been a classical model for population genetics studies on admixture.We present the results of the EPIGEN Brazil Initiative, the most ...
  • Remission and low disease activity state (LDAS) are protective of intermediate and long-term outcomes in SLE patients. Results from LUMINA (LXXVIII), a multiethnic, multicenter US cohort 
    Alarcón, Graciela S.; Ugarte Gil, Manuel Francisco; Pons-Estel, G.; Vilá, L.M.; Reveille, J.D.; McGwin, G., Jr. (SAGE Publications, 2019)
    Objective: The objective of this report is to determine the impact of remission and low disease activity state (LDAS) on damage accrual and mortality in systemic lupus erythematosus (SLE) patients. Patients and methods: ...
  • Socioeconomic inequalities in adult oral health across different ethnic groups in England 
    Delgado-Angulo, Elsa K.; Mangal, Munisha; Bernabé, Eduardo (BioMed Central, 2019)
    BACKGROUND: Ethnic inequalities in oral health among British adults remain largely unexplored. This study explored the role of socioeconomic position (SEP) in explaining ethnic inequalities in oral health; and the consistency ...
  • Understanding Risk Factors for Poor Outcomes in a Multiethnic Longitudinal Cohort: The LUMINA (Lupus in Minorities: Nature vs. Nurture) Experience (LUMINA LXXXII) 
    González, L.A.; Pons-Estel, G.J.; Toloza, S.M.A.; Ugarte Gil, Manuel Francisco; Alarcón, Graciela S. (Elsevier, 2021)
    The Lupus in Minorities: Nature Vs Nurture (LUMINA) cohort has placed Hispanics on the lupus map in the United States. Texan Hispanic and African American patients experience, overall, worse outcomes than the Caucasian and ...

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