Universidad Peruana Cayetano Heredia

Listar por tema "Drug Therapy, Combination"

Listar por tema "Drug Therapy, Combination"

Ordenar por:Orden:Resultados:

  • Assessing the HIV Care Continuum in Latin America: progress in clinical retention, cART use and viral suppression 
    Rebeiro, Peter-F.; Cesar, Carina; Shepherd, Bryan-E.; De-Boni, Raquel-B.; Cortes, Claudia-P.; Rodriguez, Fernanda; Belaunzaran-Zamudio, Pablo; Pape, Jean-W.; Padgett, Denis; Hoces, Daniel; McGowan, Catherine-C.; Cahn, Pedro (Wiley, 2016)
    INTRODUCTION: We assessed trends in HIV Care Continuum outcomes associated with delayed disease progression and reduced transmission within a large Latin American cohort over a decade: clinical retention, combination ...
  • Blood pressure response to six-minute walk test in hypertensive subjects exposed to high altitude: effects of antihypertensive combination treatment 
    Lang, Morin; Faini, Andrea; Caravita, Sergio; Bilo, Grzegorz; Anza-Ramirez, Cecilia; Villafuerte, Francisco C.; Macarlupu, Jose-Luis; Salvioni, Elisabetta; Agostoni, Piergiuseppe; Parati, Gianfranco (Elsevier, 2016)
    Background: Limited evidence exists on blood pressure (BP) responses to exercise in hypertensive subjects exposed to high altitude, and on the effects of antihypertensive treatment in this setting. We aimed to asses BP ...
  • Effect of bovine lactoferrin on the minimum inhibitory concentrations of ampicillin and trimethoprim-sulfamethoxazole for clinical Shigella spp. strains. 
    Mosquito, Susan; Zegarra, Gianina; Villanueva, Claudia; Ruiz, Joaquin; Ochoa Woodell, Theresa Jean (NRC Research Press, 2012)
    Here, we determined the effect of bovine lactoferrin (bLF) on the minimum inhibitory concentration (MIC) of ampicillin and trimethoprim-sulfamethoxazole in Shigella . Using a microdilution method, the MIC was determined ...
  • Efficacy of three different regimens of primaquine for the prevention of relapses of Plasmodium vivax malaria in the Amazon Basin of Peru 
    Durand, Salomón; Cabezas, Cesar; Lescano Guevara, Andres Guillermo; Galvez, Mariela; Gutierrez, Sonia; Arrospide, Nancy; Alvarez, Carlos; Santolalla Robles, Meddly Leslye; Bacon, David J.; Graf, Paul C. F. (American Society of Tropical Medicine and Hygiene, 2014)
    We evaluated the efficacy of three primaquine (PQ) regimes to prevent relapses with Plasmodium vivax through an open-label randomized trial in Loreto, Peru. Vivax monoinfections were treated with chloroquine for 3 days and ...
  • Factors associated with early mycological clearance in HIV-associated cryptococcal meningitis 
    Concha-Velasco, Fatima; González Lagos, Elsa Violeta; Seas Ramos, Carlos Rafael; Bustamante Rufino, Ana Beatriz (Public Library of Science, 2017)
    Introduction: The first-line combination therapy for HIV-associated cryptococcal meningitis (CM), a condition of high mortality particularly in the first two weeks of treatment, consists of amphotericin B plus flucytosine ...
  • Incidence of virological failure and major regimen change of initial combination antiretroviral therapy in the Latin America and the Caribbean: An observational cohort study 
    Cesar, C.; Jenkins, C.A.; Shepherd, B.E.; Padgett, D.; Mejía Cordero, Fernando Alonso; Ribeiro, S.R.; Cortes, C.P.; Pape, J.W.; Sierra Madero, J.; Fink, V.; Sued, O.; McGowan, C.; Cahn, P.; Grinsztejn, B.; Reyes, M.W.; Gotuzzo Herencia, José Eduardo; CCASAnet (Elsevier, 2015)
    Background: Access to combination antiretroviral therapy (ART) is expanding in Latin America (Mexico, Central America, and South America) and the Caribbean. We assessed the incidence of and factors associated with regimen ...
  • Multidrug resistant tuberculosis 
    Millard, James; Ugarte Gil, Cesar Augusto; Moore, David Alexander James (BMJ Publishing Group, 2015)
    Tuberculosis remains a major cause of morbidity and mortality globally, with an estimated nine million people developing the disease and 1.5 million deaths in 2013; equating to 4100 deaths a day.1 Nevertheless, considerable ...
  • Multidrug-resistant tuberculosis and culture conversion with bedaquiline 
    Diacon, Andreas H.; Pym, Alexander; Grobusch, Martin P.; De Los Rios, Jorge M.; Gotuzzo Herencia, José Eduardo; Vasilyeva, Irina; Leimane, Vaira; Andries, Koen; Bakare, Nyasha; De Marez, Tine; Haxaire-Theeuwes, Myriam; Lounis, Nacer; Meyvisch, Paul; De Paepe, Els; Van Heeswijk, Rolf P.G.; Dannemann, Brian (Massachusetts Medical Society, 2014)
    BACKGROUND: Bedaquiline (Sirturo, TMC207), a diarylquinoline that inhibits mycobacterial ATP synthase, has been associated with accelerated sputum-culture conversion in patients with multidrug-resistant tuberculosis, when ...
  • An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial 
    Bouton, Tara C.; Phillips, Patrick P. J.; Mitnick, Carole D.; Peloquin, Charles A.; Eisenach, Kathleen; Patientia, Ramonde F.; Lecca, Leonid; Gotuzzo Herencia, José Eduardo; Gandhi, Neel R.; Butler, Donna; Diacon, Andreas H.; Martel, Bruno; Santillan, Juan; Hunt, Kathleen Robergeau; Vargas, Dante; von Groote-Bidlingmaier, Florian; Seas Ramos, Carlos Rafael; Dianis, Nancy; Moreno-Martinez, Antonio; Horsburgh, C. Robert (BioMed Central, 2017)
    BACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the ...
  • The promises and challenges of pre-exposure prophylaxis as part of the emerging paradigm of combination HIV prevention 
    Caceres Palacios, Carlos Fernando; Koechlin, Florence; Goicochea, Pedro; Sow, Papa-Salif; O'Reilly, Kevin R.; Mayer, Kenneth H.; Godfrey-Faussett, Peter (Wiley, 2015)
    INTRODUCTION: Towards the end of the twentieth century, significant success was achieved in reducing incidence in several global HIV epidemics through ongoing prevention strategies. However, further progress in risk reduction ...
  • Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole 
    Cangalaya, Carla; Bustos Palomino, Javier Arturo; Calcina, Juan; Vargas-Calla, Ana; Mamani, Javier; Suarez, Diego; Arroyo Hurtado, Gianfranco; Gonzalez Zariquiey, Armando Emiliano; Chacaltana, Juan; Guerra-Giraldez, Cristina; Mahanty, Siddhartha; Nash, Theodore E.; García Lescano, Héctor Hugo (Public Library of Science, 2017)
    Background: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation ...
  • Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results 
    Pan, Hongchao; Peto, Richard; Henao-Restrepo, Ana-Maria; Preziosi, Marie-Pierre; Sathiyamoorthy, Vasee; Abdool Karim, Quarraisha; Alejandria, Marissa M.; Hernández García, César; Kieny, Marie-Paule; Malekzadeh, Reza; Murthy, Srinivas; Reddy, K. Srinath; Roses Periago, Mirta; Abi Hanna, Pierre; Ader, Florence; Al-Bader, Abdullah M.; Alhasawi, Almonther; Allum, Emma; Alotaibi, Athari; Alvarez-Moreno, Carlos A.; Appadoo, Sheila; Asiri, Abdullah; Aukrust, Pål; Barratt-Due, Andreas; Bellani, Samir; Branca, Mattia; Cappel-Porter, Heike B. C.; Cerrato, Nery; Chow, Ting S.; Como, Najada; Eustace, Joe; Garcia Funegra, Patricia Jannet; Godbole, Sheela; Gotuzzo Herencia, José Eduardo; Griskevicius, Laimonas; Hamra, Rasha; Hassan, Mariam; Hassany, Mohamed; Hutton, David; Irmansyah, Irmansyah; Jancoriene, Ligita; Kirwan, Jana; Kumar, Suresh; Lennon, Peter; Lopardo, Gustavo; Lydon, Patrick; Magrini, Nicola; Maguire, Teresa; Manevska, Suzana; Manuel, Oriol; McGinty, Sibylle; Medina, Marco T.; Mesa Rubio, María L.; Miranda-Montoya, Maria C.; Nel, Jeremy; Nunes, Estevao P.; Perola, Markus; Portolés, Antonio; Rasmin, Menaldi R.; Raza, Aun; Rees, Helen; Reges, Paula P. S.; Rogers, Chris A.; Salami, Kolawole; Salvadori, Marina I.; Sinani, Narvina; Sterne, Jonathan A. C.; Stevanovikj, Milena; Tacconelli, Evelina; Tikkinen, Kari A. O.; Trelle, Sven; Zaid, Hala; Røttingen, John-Arne; Swaminathan, Soumya (Massachusetts Medical Society, 2020)
    BACKGROUND: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs - remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a - in patients hospitalized with ...
  • Single-dose tafenoquine to prevent relapse of plasmodium vivax malaria 
    Lacerda, M.V.G.; Llanos Cuentas, Elmer Alejandro; Krudsood, S.; Lon, C.; Saunders, D.L.; Mohammed, R.; Yilma, D.; Pereira, D.B.; Espino, F.E.J.; Mia, R.Z.; Chuquiyauri, R.; Val, F.; Casapía, M.; Monteiro, W.M.; Brito, M.A.M.; Costa, M.R.F.; Buathong, N.; Noedl, H.; Diro, E.; Getie, S.; Wubie, K.M.; Abdissa, A.; Zeynudin, A.; Abebe, C.; Tada, M.S.; Brand, F.; Beck, H.-P.; Angus, B.; Duparc, S.; Kleim, J.-P.; Kellam, L.M.; Rousell, V.M.; Jones, S.W.; Hardaker, E.; Mohamed, K.; Clover, D.D.; Fletcher, K.; Breton, J.J.; Ugwuegbulam, C.O.; Green, J.A.; Koh, G.C.K.W. (Massachusetts Medical Society, 2019)
    BACKGROUND: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed "radical cure"). Tafenoquine ...
  • Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America 
    De-Boni, Raquel-B.; Shepherd, Bryan-E.; Grinsztejn, Beatriz; Cesar, Carina; Cortes, Claudia; Padgett, Denis; Gotuzzo Herencia, José Eduardo; Belaunzaran-Zamudio, Pablo-F.; Rebeiro, Peter-F.; Duda, Stephany-N.; McGowan, Catherine-C. (Springer, 2016)
    This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, ...
  • Successful Antiparasitic Treatment for Cysticercosis is Associated with a Fast and Marked Reduction of Circulating Antigen Levels in a Naturally Infected Pig Model 
    Gonzalez Zariquiey, Armando Emiliano; Bustos Palomino, Javier Arturo; García Lescano, Héctor Hugo; Rodriguez, Silvia; Zimic-Peralta, Mirko Juan; Castillo Berrios, Yesenia; Praet, Nicolas; Gabriel, Sarah; Gilman, Robert Hugh; Dorny, Pierre (American Society of Tropical Medicine and Hygiene, 2015)
    Taenia solium cysticercosis is a common parasitic infection of humans and pigs. We evaluated the posttreatment evolution of circulating parasite-specific antigen titers in 693 consecutive blood samples from 50 naturally ...
  • Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study 
    Llanos Cuentas, Elmer Alejandro; Lacerda, Marcus V.; Rueangweerayut, Ronnatrai; Krudsood, Srivicha; Gupta, Sandeep K.; Kochar, Sanjay K.; Arthur, Preetam; Chuenchom, Nuttagarn; Möhrle, Jörg J.; Duparc, Stephan; Ugwuegbulam, Cletus; Kleim, Jörg-Peter; Carter, Nick; Green, Justin A.; Kellam, Lynda (Elsevier, 2014)
    BACKGROUND: Clinical effectiveness of previous regimens to treat Plasmodium vivax infection have been hampered by compliance. We aimed to assess the dose-response, safety, and tolerability of single-dose tafenoquine plus ...
  • Tafenoquine versus primaquine to prevent relapse of plasmodium vivax malaria 
    Llanos Cuentas, Elmer Alejandro; Lacerda, M.V.G.; Hien, T.T.; Vélez, I.D.; Namaik-Larp, C.; Chu, C.S.; Villegas, M.F.; Val, F.; Monteiro, W.M.; Brito, M.A.M.; Costa, M.R.F.; Chuquiyauri, R.; Casapía, M.; Nguyen, C.H.; Aruachan, S.; Papwijitsil, R.; Nosten, F.H.; Bancone, G.; Angus, B.; Duparc, S.; Craig, G.; Rousell, V.M.; Jones, S.W.; Hardaker, E.; Clover, D.D.; Kendall, L.; Mohamed, K.; Koh, G.C.K.W.; Wilches, V.M.; Breton, J.J.; Green, J.A. (Massachusetts Medical Society, 2019)
    BACKGROUND: Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed "radical cure." METHODS: We ...
  • Treatment Options for Hirsutism: A Systematic Review and Network Meta-Analysis 
    Barrionuevo, Patricia; Nabhan, Mohammed; Altayar, Osama; Wang, Zhen; Erwin, Patricia J.; Asi, Noor; Martin, Kathryn A.; Murad, M. Hassan (Oxford University Press, 2018)
    Background: Several pharmacologic treatments for hirsutism are used in practice; however, their relative efficacy is unclear. Methods: We searched MEDLINE, EMBASE, and CENTRAL through January 2017 for randomized controlled ...
  • Type B Insulin Resistance in Peru 
    Zelada, Henry; Gamarra, Dante; Arbanil, Hugo; Manrique, Helard (Elsevier, 2016)
    Type B insulin resistance (IR) is a rare autoimmune disease characterized by the presence of insulin receptor autoantibodies, resulting in a marked IR inducing hyperglycemia. Our first case is a 42-year-old female with a ...

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