Listar por tema "Genetics, Population"

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  • Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals 
    Ruiz-Linares, Andrés; Adhikari, Kaustubh; Acuña-Alonzo, Victor; Quinto-Sanchez, Mirsha; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Everardo, Paola; de Avila, Francisco; Gómez-Valdés, Jorge; León-Mimila, Paola; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Burley, Mari-Wyn; Konca, Esra; de Oliveira, Marcelo Zagonel; Veronez, Mauricio Roberto; Rubio-Codina, Marta; Attanasio, Orazio; Gibbon, Sahra; Ray, Nicolas; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; Rosique, Javier; Schuler-Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria-Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; Balding, David; Gonzalez-José, Rolando (Public Library of Science, 2014)
    The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social ...
  • Ancient female philopatry, asymmetric male gene flow, and synchronous population expansion support the influence of climatic oscillations on the evolution of South American sea lion (Otaria flavescens) 
    Oliveira, Larissa Rosa de; Gehara, Marcelo C. M.; Fraga, Lúcia D.; Lopes, Fernando; Túnez, Juan Ignacio; Cassini, Marcelo H.; Majluf, Patricia; Cardenas Alayza, Susana; Pavés, Héctor J.; Crespo, Enrique Alberto; García, Nestor; Loizaga de Castro, Rocío; Hoelzel, A. Rus; Sepúlveda, Maritza; Olavarría, Carlos; Valiati, Victor Hugo; Quiñones, Renato; Pérez-Alvarez, Maria Jose; Ott, Paulo Henrique; Bonatto, Sandro L. (Public Library of Science, 2017)
    The South American sea lion (Otaria flavescens) is widely distributed along the southern Atlantic and Pacific coasts of South America with a history of significant commercial exploitation. We aimed to evaluate the population ...
  • Bayesian inferences suggest that Amazon Yunga Natives diverged from Andeans less than 5000 ybp: Implications for South American prehistory 
    Scliar, Marilia O.; Gouveia, Mateus H.; Benazzo, Andrea; Ghirotto, Silvia; Fagundes, Nelson J.; Leal, Thiago P.; Magalhães, Wagner C.; Pereira, Latife; Rodrigues, Maira R.; Soares-Souza, Giordano B.; Cabrera, Lilia; Berg, Douglas E.; Gilman, Robert Hugh; Bertorelle, Giorgio; Tarazona-Santos, Eduardo (BioMed Central, 2014)
    Background: Archaeology reports millenary cultural contacts between Peruvian Coast-Andes and the Amazon Yunga, a rainforest transitional region between Andes and Lower Amazonia. To clarify the relationships between cultural ...
  • Evidence for temporal population replacement and the signature of ecological adaptation in a major Neotropical malaria vector in Amazonian Peru 
    Lainhart, William; Bickersmith, Sara A.; Nadler, Kyle J.; Moreno, Marta; Saavedra Romero, Marlon Pierino; Chu, Virginia M.; Ribolla, Paulo E.; Vinetz, Joseph Michael; Conn, Jan E. (BioMed Central, 2015)
    BACKGROUND: The major Neotropical malaria vector, Anopheles darlingi, was reintroduced into the Iquitos, Loreto, Peru area during the early 1990s, where it displaced other anophelines and caused a major malaria epidemic. ...
  • The Genetic Diversity of the Americas 
    Adhikari, Kaustubh; Chacón-Duque, Juan Camilo; Mendoza-Revilla, Javier; Fuentes-Guajardo, Macarena; Ruiz-Linares, Andrés (Annual Reviews, 2017)
    The history of the Americas involved the encounter of millions of Native Americans, Europeans, and Africans. A variable admixture of these three continental groups has taken place throughout the continent, influenced by ...
  • A global reference for human genetic variation 
    1000 Genomes Project; Auton, A.; Abecasis, G.R.; Altshuler, D.M.; Durbin, R.M.; Bentley, D.R.; Chakravarti, A.; Clark, A.G.; Donnelly, P.; Eichler, E.E.; Flicek, P.; Gabriel, S.B.; Gibbs, R.A.; Green, E.D.; Hurles, M.E.; Knoppers, B.M.; Korbel, J.O.; Lander, E.S.; Lee, C.; Lehrach, H.; Mardis, E.R.; Marth, G.T.; McVean, G.A.; Nickerson, D.A.; Schmidt, J.P.; Sherry, S.T.; Wang, J.; Wilson, R.K.; Boerwinkle, E.; Doddapaneni, H.; Han, Y.; Korchina, V.; Kovar, C.; Lee, S.; Muzny, D.; Reid, J.G.; Zhu, Y.; Chang, Y.; Feng, Q.; Fang, X.; Guo, X.; Jian, M.; Jiang, H.; Jin, X.; Lan, T.; Li, G.; Li, J.; Li, Y.; Liu, S.; Liu, X.; Lu, Y.; Ma, X.; Tang, M.; Wang, B.; Wang, G.; Wu, H.; Wu, R.; Xu, X.; Yin, Y.; Zhang, D.; Zhang, W.; Zhao, J.; Zhao, M.; Zheng, X.; Gupta, N.; Gharani, N.; Toji, L.H.; Gerry, N.P.; Resch, A.M.; Barker, J.; Clarke, L.; Gil, L.; Hunt, S.E.; Kelman, G.; Kulesha, E.; Leinonen, R.; McLaren, W.M.; Radhakrishnan, R.; Roa, A.; Smirnov, D.; Smith, R.E.; Streeter, I.; Thormann, A.; Toneva, I.; Vaughan, B.; Zheng-Bradley, X.; Grocock, R.; Humphray, S.; James, T.; Kingsbury, Z.; Sudbrak, R.; Albrecht, M.W.; Amstislavskiy, V.S.; Borodina, T.A.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.; Fulton, L.; Ananiev, V.; Belaia, Z.; Beloslyudtsev, D.; Bouk, N.; Chen, C.; Church, D.; Cohen, R.; Cook, C.; Garner, J.; Hefferon, T.; Kimelman, M.; Liu, C.; Lopez, J.; Meric, P.; O'Sullivan, C.; Ostapchuk, Y.; Phan, L.; Ponomarov, S.; Schneider, V.; Shekhtman, E.; Sirotkin, K.; Slotta, D.; Zhang, H.; Balasubramaniam, S.; Burton, J.; Danecek, P.; Keane, T.M.; Kolb-Kokocinski, A.; McCarthy, S.; Stalker, J.; Quail, M.; Davies, C.J.; Gollub, J.; Webster, T.; Wong, B.; Zhan, Y.; Campbell, C.L.; Kong, Y.; Marcketta, A.; Yu, F.; Antunes, L.; Bainbridge, M.; Sabo, A.; Huang, Z.; Coin, L.J.M.; Fang, L.; Li, Q.; Li, Z.; Lin, H.; Liu, B.; Luo, R.; Shao, H.; Xie, Y.; Ye, C.; Yu, C.; Zhang, F.; Zheng, H.; Zhu, H.; Alkan, C.; Dal, E.; Kahveci, F.; Garrison, E.P.; Kural, D.; Lee, W.-P.; Leong, W.F.; Stromberg, M.; Ward, A.N.; Wu, J.; Zhang, M.; Daly, M.J.; DePristo, M.A.; Handsaker, R.E.; Banks, E.; Bhatia, G.; Del Angel, G.; Genovese, G.; Li, H.; Kashin, S.; McCarroll, S.A.; Nemesh, J.C.; Poplin, R.E.; Yoon, S.C.; Lihm, J.; Makarov, V.; Gottipati, S.; Keinan, A.; Rodriguez-Flores, J.L.; Rausch, T.; Fritz, M.H.; Stütz, A.M.; Beal, K.; Datta, A.; Herrero, J.; Ritchie, G.R.S.; Zerbino, D.; Sabeti, P.C.; Shlyakhter, I.; Schaffner, S.F.; Vitti, J.; Cooper, D.N.; Ball, E.V.; Stenson, P.D.; Barnes, B.; Bauer, M.; Cheetham, R.K.; Cox, A.; Eberle, M.; Kahn, S.; Murray, L.; Peden, J.; Shaw, R.; Kenny, E.E.; Batzer, M.A.; Konkel, M.K.; Walker, J.A.; MacArthur, D.G.; Lek, M.; Herwig, R.; Ding, L.; Koboldt, D.C.; Larson, D.; Ye, K.; Gravel, S.; Swaroop, A.; Chew, E.; Lappalainen, T.; Erlich, Y.; Gymrek, M.; Willems, T.F.; Simpson, J.T.; Shriver, M.D.; Rosenfeld, J.A.; Bustamante, C.D.; Montgomery, S.B.; De La Vega, F.M.; Byrnes, J.K.; Carroll, A.W.; DeGorter, M.K.; Lacroute, P.; Maples, B.K.; Martin, A.R.; Moreno-Estrada, A.; Shringarpure, S.S.; Zakharia, F.; Halperin, E.; Baran, Y.; Cerveira, E.; Hwang, J.; Malhotra, A.; Plewczynski, D.; Radew, K.; Romanovitch, M.; Zhang, C.; Hyland, F.C.L.; Craig, D.W.; Christoforides, A.; Homer, N.; Izatt, T.; Kurdoglu, A.A.; Sinari, S.A.; Squire, K.; Xiao, C.; Sebat, J.; Antaki, D.; Gujral, M.; Noor, A.; Ye, K.; Burchard, E.G.; Hernandez, R.D.; Gignoux, C.R.; Haussler, D.; Katzman, S.J.; Kent, W.J.; Howie, B.; Ruiz-Linares, A.; Dermitzakis, E.T.; Devine, S.E.; Kang, H.M.; Kidd, J.M.; Blackwell, T.; Caron, S.; Chen, W.; Emery, S.; Fritsche, L.; Fuchsberger, C.; Jun, G.; Li, B.; Lyons, R.; Scheller, C.; Sidore, C.; Song, S.; Sliwerska, E.; Taliun, D.; Tan, A.; Welch, R.; Wing, M.K.; Zhan, X.; Awadalla, P.; Hodgkinson, A.; Li, Y.; Shi, X.; Quitadamo, A.; Lunter, G.; Marchini, J.L.; Myers, S.; Churchhouse, C.; Delaneau, O.; Gupta-Hinch, A.; Kretzschmar, W.; Iqbal, Z.; Mathieson, I.; Menelaou, A.; Rimmer, A.; Xifara, D.K.; Oleksyk, T.K.; Fu, Y.; Liu, X.; Xiong, M.; Jorde, L.; Witherspoon, D.; Xing, J.; Browning, B.L.; Browning, S.R.; Hormozdiari, F.; Sudmant, P.H.; Khurana, E.; Tyler-Smith, C.; Albers, C.A.; Ayub, Q.; Chen, Y.; Colonna, V.; Jostins, L.; Walter, K.; Xue, Y.; Gerstein, M.B.; Abyzov, A.; Balasubramanian, S.; Chen, J.; Clarke, D.; Fu, Y.; Harmanci, A.O.; Jin, M.; Lee, D.; Liu, J.; Mu, X.J.; Zhang, J.; Zhang, Y.; Hartl, C.; Shakir, K.; Degenhardt, J.; Meiers, S.; Raeder, B.; Casale, F.P.; Stegle, O.; Lameijer, E.-W.; Hall, I.; Bafna, V.; Michaelson, J.; Gardner, E.J.; Mills, R.E.; Dayama, G.; Chen, K.; Fan, X.; Chong, Z.; Chen, T.; Chaisson, M.J.; Huddleston, J.; Malig, M.; Nelson, B.J.; Parrish, N.F.; Blackburne, B.; Lindsay, S.J.; Ning, Z.; Zhang, Y.; Lam, H.; Sisu, C.; Challis, D.; Evani, U.S.; Lu, J.; Nagaswamy, U.; Yu, J.; Li, W.; Habegger, L.; Yu, H.; Cunningham, F.; Dunham, I.; Lage, K.; Jespersen, J.B.; Horn, H.; Kim, D.; Desalle, R.; Narechania, A.; Sayres, M.A.W.; Mendez, F.L.; Poznik, G.D.; Underhill, P.A.; Mittelman, D.; Banerjee, R.; Cerezo, M.; Fitzgerald, T.W.; Louzada, S.; Massaia, A.; Yang, F.; Kalra, D.; Hale, W.; Dan, X.; Barnes, K.C.; Beiswanger, C.; Cai, H.; Cao, H.; Henn, B.; Jones, D.; Kaye, J.S.; Kent, A.; Kerasidou, A.; Mathias, R.; Ossorio, P.N.; Parker, M.; Rotimi, C.N.; Royal, C.D.; Sandoval, K.; Su, Y.; Tian, Z.; Tishkoff, S.; Via, M.; Wang, Y.; Yang, H.; Yang, L.; Zhu, J.; Bodmer, W.; Bedoya, G.; Cai, Z.; Gao, Y.; Chu, J.; Peltonen, L.; Garcia-Montero, A.; Orfao, A.; Dutil, J.; Martinez-Cruzado, J.C.; Mathias, R.A.; Hennis, A.; Watson, H.; McKenzie, C.; Qadri, F.; LaRocque, R.; Deng, X.; Asogun, D.; Folarin, O.; Happi, C.; Omoniwa, O.; Stremlau, M.; Tariyal, R.; Jallow, M.; Joof, F.S.; Corrah, T.; Rockett, K.; Kwiatkowski, D.; Kooner, J.; Hien, T.T.; Dunstan, S.J.; ThuyHang, N.; Fonnie, R.; Garry, R.; Kanneh, L.; Moses, L.; Schieffelin, J.; Grant, D.S.; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; Saleheen, D.; Rasheed, A.; Brooks, L.D.; Felsenfeld, A.L.; McEwen, J.E.; Vaydylevich, Y.; Duncanson, A.; Dunn, M.; Schloss, J.A. (Springer Nature, 2015)
    The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report ...
  • A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia 
    Adhikari, K.; Mendoza-Revilla, J.; Sohail, A.; Fuentes-Guajardo, M.; Lampert, J.; Chacón-Duque, J.C.; Hurtado, M.; Villegas, V.; Granja, V.; Acuña-Alonzo, V.; Jaramillo, C.; Arias, W.; Lozano, R.B.; Everardo, P.; Gómez-Valdés, J.; Villamil-Ramírez, H.; Silva de Cerqueira, C.C.; Hunemeier, T.; Ramallo, V.; Schuler-Faccini, L.; Salzano, F.M.; Gonzalez-José, R.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Bedoya, G.; Rothhammer, F.; Tobin, D.J.; Fumagalli, M.; Balding, D.; Ruiz-Linares, A. (Springer Nature, 2019)
    We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation ...
  • Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network 
    Escalante, Ananias A.; Ferreira, Marcelo U.; Vinetz, Joseph Michael; Volkman, Sarah K.; Cui, Liwang; Gamboa Vilela, Dionicia Baziliza; Krogstad, Donald J.; Barry, Alyssa E.; Carlton, Jane M.; van Eijk, Anna Maria; Pradhan, Khageswar; Mueller, Ivo; Greenhouse, Bryan; Pacheco, M. Andreina; Vallejo, Andres F.; Herrera, Socrates; Felger, Ingrid (American Society of Tropical Medicine and Hygiene, 2015)
    Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being ...
  • Microgeographical structure in the major Neotropical malaria vector Anopheles darlingi using microsatellites and SNP markers 
    Campos, Melina; Conn, Jan E.; Alonso, Diego Peres; Vinetz, Joseph Michael; Emerson, Kevin J.; Ribolla, Paulo Eduardo Martins (BioMed Central, 2017)
    BACKGROUND: In recent decades, throughout the Amazon Basin, landscape modification contributing to profound ecological change has proceeded at an unprecedented rate. Deforestation that accompanies human activities can ...
  • Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations 
    Kehdy, F.S.G.; Gouveia, M.H.; Machado, M.; Magalhães, W.C.S.; Horimoto, A.R.; Horta, B.L.; Moreira, R.G.; Leal, T.P.; Scliar, M.O.; Soares-Souza, G.B.; Rodrigues-Soares, F.; Araújo, G.S.; Zamudio, R.; Sant Anna, H.P.; Santos, H.C.; Duarte, N.E.; Fiaccone, R.L.; Figueiredo, C.A.; Silva, T.M.; Costa, G.N.O.; Beleza, S.; Berg, D.E.; Cabrera, L.; Debortoli, G.; Duarte, D.; Ghirotto, S.; Gilman, Robert Hugh; Gonçalves, V.F.; Marrero, A.R.; Muniz, Y.C.; Weissensteiner, H.; Yeager, M.; Rodrigues, L.C.; Barreto, M.L.; Lima-Costa, M.F.; Pereira, A.C.; Rodrigues, M.R.; Tarazona-Santos, E. (National Academy of Sciences, 2015)
    While South Americans are underrepresented in human genomic diversity studies, Brazil has been a classical model for population genetics studies on admixture.We present the results of the EPIGEN Brazil Initiative, the most ...
  • Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World 
    Yalcindag, Erhan; Rougeron, Virginie; Elguero, Eric; Arnathau, Céline; Durand, Patrick; Brisse, Sylvain; Diancourt, Laure; Aubouy, Agnes; Becquart, Pierre; D'Alessandro, Umberto; Fontenille, Didier; Gamboa Vilela, Dionicia Baziliza; Maestre, Amanda; Ménard, Didier; Musset, Lisie; Noya, Oscar; Veron, Vincent; Wide, Albina; Carme, Bernard; Legrand, Eric; Chevillon, Christine; Ayala, Francisco J.; Renaud, Francois; Prugnolle, Franck (Wiley, 2014)
    Pathogens, which have recently colonized a new host species or new populations of the same host, are interesting models for understanding how populations may evolve in response to novel environments. During its colonization ...
  • Plasmodium vivax Diversity and Population Structure across Four Continents 
    Koepfli, Cristian; Rodrigues, Priscila T.; Antao, Tiago; Orjuela-Sanchez, Pamela; Van den Eede, Peter; Gamboa Vilela, Dionicia Baziliza; van Hong, Nguyen; Bendezu, Jorge; Erhart, Annette; Barnadas, Celine; Ratsimbasoa, Arsene; Menard, Didier; Severini, Carlo; Menegon, Michela; Nour, Bakri Y. M.; Karunaweera, Nadira; Mueller, Ivo; Ferreira, Marcelo U.; Felger, Ingrid (Public Library of Science, 2015)
    Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity, genotyping data ...
  • Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe 
    Sikora, Martin; Carpenter, Meredith L.; Moreno-Estrada, Andres; Henn, Brenna M.; Underhill, Peter A.; Sanchez-Quinto, Federico; Zara, Ilenia; Pitzalis, Maristella; Sidore, Carlo; Busonero, Fabio; Maschio, Andrea; Angius, Andrea; Jones, Chris; Mendoza-Revilla, Javier; Nekhrizov, Georgi; Dimitrova, Diana; Theodossiev, Nikola; Harkins, Timothy T.; Keller, Andreas; Maixner, Frank; Zink, Albert; Abecasis, Goncalo; Sanna, Serena; Cucca, Francesco; Bustamante, Carlos D. (Public Library of Science, 2014)
    Genome sequencing of the 5,300-year-old mummy of the Tyrolean Iceman, found in 1991 on a glacier near the border of Italy and Austria, has yielded new insights into his origin and relationship to modern European populations. ...
  • The Simons Genome Diversity Project: 300 genomes from 142 diverse populations 
    Mallick, Swapan; Li, Heng; Lipson, Mark; Mathieson, Iain; Gymrek, Melissa; Racimo, Fernando; Zhao, Mengyao; Chennagiri, Niru; Nordenfelt, Susanne; Tandon, Arti; Skoglund, Pontus; Lazaridis, Iosif; Sankararaman, Sriram; Fu, Qiaomei; Rohland, Nadin; Renaud, Gabriel; Erlich, Yaniv; Willems, Thomas; Gallo López-Aliaga, Carla Maria; Spence, Jeffrey-P.; Song, Yun-S.; Poletti, Giovanni; Balloux, Francois; van-Driem, George; de-Knijff, Peter; Gallego Romero, Irene; Jha, Aashish-R.; Behar, Doron-M.; Bravi, Claudio-M.; Capelli, Cristian; Hervig, Tor; Moreno-Estrada, Andres; Posukh, Olga-L.; Balanovska, Elena; Balanovsky, Oleg; Karachanak-Yankova, Sena; Sahakyan, Hovhannes; Toncheva, Draga; Yepiskoposyan, Levon; Tyler-Smith, Chris; Xue, Yali; Abdullah, M. Syafiq; Ruiz-Linares, Andres; Beall, Cynthia-M.; Di-Rienzo, Anna; Jeong, Choongwon; Starikovskaya, Elena-B.; Metspalu, Ene; Parik, Juri; Villems, Richard; Henn, Brenna-M.; Hodoglugil, Ugur; Mahley, Robert; Sajantila, Antti; Stamatoyannopoulos, George; Wee, Joseph-T. S.; Khusainova, Rita; Khusnutdinova, Elza; Litvinov, Sergey; Ayodo, George; Comas, David; Hammer, Michael-F.; Kivisild, Toomas; Klitz, William; Winkler, Cheryl-A.; Labuda, Damian; Bamshad, Michael; Jorde, Lynn-B.; Tishkoff, Sarah-A.; Watkins, W. Scott; Metspalu, Mait; Dryomov, Stanislav; Sukernik, Rem; Singh, Lalji; Thangaraj, Kumarasamy; Paabo, Svante; Kelso, Janet; Patterson, Nick; Reich, David (Springer Nature, 2016)
    Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human ...
  • Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile 
    Lorenzo Bermejo, Justo; Boekstegers, Felix; Gonzalez Silos, Rosa; Marcelain, Katherine; Baez Benavides, Pablo; Barahona Ponce, Carol; Muller, Bettina; Ferreccio, Catterina; Koshiol, Jill; Fischer, Christine; Peil, Barbara; Sinsheimer, Janet; Fuentes Guajardo, Macarena; Barajas, Olga; Gonzalez-Jose, Rolando; Bedoya, Gabriel; Catira Bortolini, Maria; Canizales-Quinteros, Samuel; Gallo López-Aliaga, Carla Maria; Ruiz Linares, Andres; Rothhammer, Francisco (Public Library of Science, 2017)
    Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and ...
  • Whole-Genome sequencing uncovers the genetic basis of chronic mountain sickness in andean highlanders 
    Zhou, Dan; Udpa, Nitin; Ronen, Roy; Stobdan, Tsering; Liang, Junbin; Appenzeller, Otto; Zhao, Huiwen W.; Yin, Yi; Du, Yuanping; Guo, Lixia; Cao, Rui.; Wang, Yu; Jin, Xin; Huang, Chen; Jia, Wenlong; Cao, Dandan; Guo, Guangwu; Gamboa, Jorge L.; Villafuerte, Francisco C.; Callacondo, David; Xue, Jin; Liu, Siqi; Frazer, Kelly A.; Li, Yingrui; Bafna, Vineet; Haddad, Gabriel G. (Elsevier, 2013)
    The hypoxic conditions at high altitudes present a challenge for survival, causing pressure for adaptation. Interestingly, many highaltitude denizens (particularly in the Andes) are maladapted, with a condition known as ...

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