Listar por tema "Mutagenicity Tests"

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Preclinical studies on the pharmacokinetics, safety, and toxicology of oxfendazole: toward first in human studies

Codd, Ellen E.; Ng, Hanna H.; McFarlane, Claire; Riccio, Edward S.; Doppalapudi, Rupa; Mirsalis, Jon C.; Horton, R. John; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; Gilman, Robert Hugh (SAGE Publications, 2015)

A 2-week study in rats identified target organs of oxfendazole toxicity to be bone marrow, epididymis, liver, spleen, testis, and thymus. Female rats had greater oxfendazole exposure and exhibited toxicities at lower doses ...