Browsing by Subject "Mutant Proteins"

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Diverging mechanisms of activation of chemokine receptors revealed by novel chemokine agonists

Sarmiento, J.; Shumate, C.; Suetomi, K.; Ravindran, A.; Villegas, L.; Rajarathnam, K.; Navarro, J. (Public Library of Science, 2011)

CXCL8/interleukin-8 is a pro-inflammatory chemokine that triggers pleiotropic responses, including inflammation, angiogenesis, wound healing and tumorigenesis. We engineered the first selective CXCR1 agonists on the basis ...

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