Browsing by Subject "PZAse activity"

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PncA gene expression and prediction factors on pyrazinamide resistance in Mycobacterium tuberculosis

Sheen Cortavarria, Patricia; Lozano, Katherine; Gilman, Robert Hugh; Valencia, Hugo J.; Loli, Sebastian; Fuentes, Patricia; Grandjean, Louis; Zimic-Peralta, Mirko Juan (Elsevier, 2013)

Mutations in the pyrazinamidase (PZAse) coding gene, pncA, have been considered as the main cause of pyrazinamide (PZA) resistance in Mycobacterium tuberculosis. However, recent studies suggest there is no single mechanism ...

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