Listar por tema "area under the curve"

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  • Characterization of a novel cathepsin L-like protease from Taenia solium metacestodes for the immunodiagnosis of porcine cysticercosis 
    Leon-Janampa, Nancy; Liendo, Ruddy; Gilman, Robert Hugh; Padilla, Carlos; García Lescano, Héctor Hugo; Gonzales, Armando; Sheen Cortavarria, Patricia; Pajuelo Travezaño, Monica Jhenny; Zimic-Peralta, Mirko Juan; Cysticercosis Working Group in Peru (Elsevier, 2019)
    Porcine cysticercosis is an endemic parasitic disease caused by infection with Taenia solium that is found predominantly in developing countries. In order to aid in the development of simple diagnostic approaches, ...
  • Intra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid 
    Requena-Méndez, A.; Davies, G.; Waterhouse, D.; Ardrey, A.; Jave, O.; López-Romero, S.L.; Ward, S.A.; Moore, David Alexander James (Oxford University Press, 2018)
    Background: Poor response to TB therapy might be attributable to subtherapeutic levels in drug-compliant patients. Pharmacokinetic parameters can be affected by comorbidities or the interaction of drugs with food. Objectives ...
  • Mycobacterium tuberculosis-specific cytokine biomarkers for the diagnosis of childhood TB in a TB-endemic setting 
    Sudbury, Eva L.; Otero Vegas, Larissa; Tebruegge, Marc; Messina, Nicole L.; Seas Ramos, Carlos Rafael; Montes Delgado, Martin; Rios, Julia; Germano, Susie; Gardiner, Kaya; Clifford, Vanessa; Gotuzzo Herencia, José Eduardo; Curtis, Nigel (Elsevier, 2019)
    The tuberculin skin test and interferon-gamma release assays have limitations in diagnosing tuberculosis (TB), particularly in children. This study investigated the performance of candidate M. tuberculosis-specific cytokine ...
  • Pharmacokinetics and absorption of paromomycin and gentamicin from topical creams used to treat cutaneous leishmaniasis 
    Ravis, William R.; Llanos Cuentas, Elmer Alejandro; Sosa, Nestor; Kreishman-Deitrick, Mara; Kopydlowski, Karen M.; Nielsen, Carl; Smith, Kristen S.; Smith, Philip L.; Ransom, Janet H.; Lin, Yuh-Jing; Grogl, Max (American Society for Microbiology, 2013)
    This study evaluated the pharmacokinetics of topical creams containing 15% paromomycin (“paromomycin alone”) and 15% paromomycin plus 0.5% gentamicin (WR 279,396) in patients with cutaneous leishmaniasis. The investigational ...
  • Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: A randomized, placebo-controlled first-inhuman single-dose escalation study 
    An, G.; Murry, D.J.; Gajurel, K.; Bach, T.; Deye, G.; Stebounova, L.V.; Codd, E.E.; Horton, J.; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; Ince, D.; Hodgson-Zingman, D.; Nomicos, E.Y.H.; Conrad, T.; Kennedy, J.; Jones, W.; Gilman, Robert Hugh; Winokur, P. (American Society for Microbiology, 2019)
    Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of ...
  • Role of exhaled nitric oxide as a predictor of atopy 
    Romero Rivero, Karina Maribel; Robinson, Colin L.; Baumann, Lauren M.; Gilman, Robert Hugh; Hamilton, Robert G.; Hansel, Nadia N.; Checkley, William (BioMed Central, 2013)
    Background: The fractional exhaled nitric oxide (FeNO) is a quantitative, noninvasive and safe measure of airways inflammation that may complement the assessment of asthma. Elevations of FeNO have recently been found to ...
  • Validation of the Spanish Center for Epidemiological Studies Depression and Zung Self-Rating Depression Scales: A Comparative Validation Study 
    Ruiz-Grosso, P.; Loret de Mola, C.; Vega Dienstmaier, Johann Martín; Arévalo Flores, Jorge Martín; Chavez, K.; Vilela, A.; Lazo Porras, María de los Ángeles; Huapaya, J. (Public Library of Science, 2012)
    Background: Depressive disorders are leading contributors to burden of disease in developing countries. Research aiming to improve their diagnosis and treatment is fundamental in these settings, and psychometric tools are ...

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