Listar por tema "discrete typing unit"

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  • Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains 
    Reis-Cunha, J.L.; Rodrigues-Luiz, G.F.; Valdivia, H.O.; Baptista, R.P.; Mendes, T.A.O.; Loss de Morais, G.; Guedes, R.; Macedo, A.M.; Bern, C.; Gilman, Robert Hugh; Talavera Lopez, C.; Andersson, B.; Vasconcelos, A.T.; Bartholomeu, D.C. (BioMed Central, 2015)
    Background: Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI-TcVI. CL Brener, the reference strain of the T. cruzi genome project, is a hybrid ...
  • Deep sequencing to detect diversity of Trypanosoma cruzi infection in patients co-infected with HIV and Chagas disease 
    Bowman, Natalie M.; Balasubramanian, Sujata; Gilman, Robert Hugh; Parobek, Christian; Calderón Sánchez, Maritza Mercedes; Waltmann, Andreea; Messenger, Louisa A.; Sanchez, Leny; Bern, Caryn; Juliano, Jonathan J. (Oxford University Press, 2021)
    Chagas disease, caused by Trypanosoma cruzi, can reactivate and cause severe acute disease in immunocompromised patients such as those infected with HIV. We conducted amplicon deep sequencing of a 327-base pair fragment ...

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