Listar por tema "drug metabolism"

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Comparison of gene expression patterns among Leishmania braziliensis clinical isolates showing a different in vitro susceptibility to pentavalent antimony

Adaui, V.; Schnorbusch, K.; Zimic-Peralta, Mirko Juan; Gutirrez, A.; Decuypere, S.; Vanaerschot, M.; De Doncker, S.; Maes, I.; Llanos Cuentas, Elmer Alejandro; Chappuis, F.; Arvalo, J.; Dujardin, J.-C. (Crambridge University Press, 2011)

Introduction. Evaluation of Leishmania drug susceptibility depends on in vitro SbV susceptibility assays, which are labour-intensive and may give a biased view of the true parasite resistance. Molecular markers are urgently ...
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: A randomized, placebo-controlled first-inhuman single-dose escalation study

An, G.; Murry, D.J.; Gajurel, K.; Bach, T.; Deye, G.; Stebounova, L.V.; Codd, E.E.; Horton, J.; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; Ince, D.; Hodgson-Zingman, D.; Nomicos, E.Y.H.; Conrad, T.; Kennedy, J.; Jones, W.; Gilman, Robert Hugh; Winokur, P. (American Society for Microbiology, 2019)

Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of ...

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