Listar por tema "drug targeting"

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  • CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis 
    Menezes, Soraya Maria; Decanine, Daniele; Brassat, David; Khouri, Ricardo; Schnitman, Saul V.; Kruschewsky, Ramon; López, Giovanni; Alvarez, Carolina; Talledo Albujar, Michael John; Gotuzzo Herencia, José Eduardo; Vandamme, Anne-Mieke; Galvão-Castro, Bernardo; Liblau, Roland; Weyenbergh, Johan Van (BioMed Central, 2014)
    Background: Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no ...
  • Neurocysticercosis: A natural human model of epileptogenesis 
    Nash, T.E.; Mahanty, S.; Loeb, J.A.; Theodore, W.H.; Friedman, A.; Sander, J.W.; Singh, G.; Cavalheiro, E.; Del Brutto, O.H.; Takayanagui, O.M.; Fleury, A.; Verastegui Pimentel, Manuela Renee; Preux, P.-M.; Montano, S.; Pretell, E.J.; White, A.C. Jr.; Gonzales, A.E.; Gilman, Robert Hugh; García Lescano, Héctor Hugo (Wiley, 2015)
    Objective: To develop a better understanding of mechanisms of seizures and long-term epileptogenesis using neurocysticercosis. Methods A workshop was held bringing together experts in epilepsy and epileptogenesis and ...
  • Series "matrix metalloproteinases in lung health and disease": Matrix metalloproteinases in tuberculosis 
    Elkington, P.T.; Ugarte Gil, Cesar Augusto; Friedland, J.S. (European Respiratory Society, 2011)
    Tuberculosis (TB) remains a global health pandemic. Infection is spread by the aerosol route and Mycobacterium tuberculosis must drive lung destruction to be transmitted to new hosts. Such inflammatory tissue damage is ...

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