Listar por tema "hepcidin"

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Adaptation of iron requirement to hypoxic conditions at high altitude

Gassmann, Max; Muckenthaler, Martina U. (American Physiological Society, 2015)

Adequate acclimatization time to enable adjustment to hypoxic conditions is one of the most important aspects for mountaineers ascending to high altitude. Accordingly, most reviews emphasize mechanisms that cope with reduced ...
A Critical Analysis of the Automated Hematology Assessment in Pregnant Women at Low and at High Altitude: Association between Red Blood Cells, Platelet Parameters, and Iron Status

Figueroa-Mujica, R.; Ccahuantico, L.A.; Ccorahua-Rios, M.S.; Sanchez-Huaman, J.J.; Vásquez-Velasquez, Cinthya; Ponce-Huarancca, J.M.; Rozas-Gamarra, R.E.; Gonzales Rengifo, Gustavo Francisco (MDPI, 2022)

The objectives of the study were to determine differences in the parameters of red blood cells (RBC), white blood cells (WBC), and platelets at low altitude (LA) and at high altitude (HA) and with the gestation being ...
Is the prevalence of anemia in children living at high altitudes real? An observational study in Peru

Choque-Quispe, Benita Maritza; Alarcón Yaquetto, Dulce Esperanza; Paredes-Ugarte, Wilber; Zaira, Arturo; Ochoa, Adelayda; Gonzales Rengifo, Gustavo Francisco (Wiley, 2020)

Abstract: Anemia diagnosis in populations residing at high altitude (HA) involves an adjustment of hemoglobin (Hb) values owing to the increase in its concentration with altitude. The suitability of the adjustment has been ...
Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice

Díaz, Víctor; Gammella, Elena; Recalcati, Stefania; Santambrogio, Paolo; Naldi, Arianne Monge; Vogel, Johannes; Gassmann, Max; Cairo, Gaetano (Wiley, 2013)

The liver-derived peptide hepcidin controls the balance between iron demand and iron supply. By inhibiting the iron export activity of ferroportin, hepcidin modulates iron absorption and delivery from the body's stores. ...
Regulation of hepcidin expression at high altitude

Talbot, N.P.; Lakhal, S.; Smith, T.G.; Privat, C.; Nickol, A.H.; Rivera Chira, Maria Concepcion; León-Velarde, Fabiola; Dorrington, K.L.; Mole, D.R.; Robbins, P.A. (Elsevier, 2012)

Enhanced erythropoietic drive and iron deficiency both influence iron homeostasis through the suppression of the iron regulatory hormone hepcidin. Hypoxia also suppresses hepcidin through a mechanism that is unknown. We ...

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