Listar por tema "heterozygosity"

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  • Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains 
    Reis-Cunha, J.L.; Rodrigues-Luiz, G.F.; Valdivia, H.O.; Baptista, R.P.; Mendes, T.A.O.; Loss de Morais, G.; Guedes, R.; Macedo, A.M.; Bern, C.; Gilman, Robert Hugh; Talavera Lopez, C.; Andersson, B.; Vasconcelos, A.T.; Bartholomeu, D.C. (BioMed Central, 2015)
    Background: Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI-TcVI. CL Brener, the reference strain of the T. cruzi genome project, is a hybrid ...
  • Facial asymmetry and genetic ancestry in Latin American admixed populations 
    Quinto-Sánchez, Mirsha; Adhikari, K.; Acuña-Alonzo, V.; Cintas, C.; Silva De Cerqueira, C.C.; Ramallo, V.; Castillo, L.; Farrera, A.; Jaramillo, C.; Arias, W.; Fuentes, M.; Everardo, P.; De Avila, F.; Gomez-Valdés, J.; Hünemeier, T.; Gibbon, S.; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; Rosique, J.; Bortolini, M.C.; Canizales-Quinteros, S.; Rothhammer, F.; Bedoya, G.; Ruiz-Linares, A.; González-José, R. (Wiley, 2015)
    Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of ...
  • Identification of Main Genetic Causes Responsible for Non-Syndromic Hearing Loss in a Peruvian Population 
    Figueroa Ildefonso, Erick Gianpierre; Bademci, Guney; Rajabli, Farid; Cornejo-Olivas, Mario; Villanueva, Ruy Diego Chacon; Badillo-Carrillo, Rodolfo; Inca-Martinez, Miguel; Neyra, Karina Milla; Sineni, Claire; Tekin, Mustafa (MDPI, 2019)
    Hearing loss (HL) is a common sensory disorder affecting over 5% of the global population. The etiology underlying HL includes congenital and acquired causes; genetic factors are the main cause in over 50% of congenital ...
  • Plasmodium vivax sub-patent infections after radical treatment are common in peruvian patients: Results of a 1-year prospective cohort study 
    van den Eede, P.; Soto-Calle, V.E.; Delgado Ratto, Christopher; Gamboa Vilela, Dionicia Baziliza; Grande, T.; Rodriguez, H.; Llanos Cuentas, Elmer Alejandro; Anné, J.; D'Alessandro, U.; Erhart, A. (Public Library of Science, 2011)
    Background: There is an increasing body of literature reporting treatment failure of the currently recommended radical treatment of Plasmodium vivax infections. As P. vivax is the main malaria species outside the African ...
  • Sexual reproduction in a natural Trypanosoma cruzi population 
    Berry, Alexander S. F.; Salazar Sánchez, Renzo Sadath; Castillo Neyra, Ricardo; Borrini-Mayori, Katty; Chipana-Ramos, Claudia; Vargas-Maquera, Melina; Ancca-Juarez, Jenny; Naquira Velarde, Cesar Gabriel; Levy, Michael Z.; Brisson, Dustin (Public Library of Science, 2019)
    Background: Sexual reproduction provides an evolutionary advantageous mechanism that combines favorable mutations that have arisen in separate lineages into the same individual. This advantage is especially pronounced in ...

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