Listar por tema "in vivo study"

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  • Endogenous α-calcitonin-gene-related peptide promotes exercise-induced, physiological heart hypertrophy in mice 
    Schuler, B.; Rieger, G.; Gubser, M.; Arras, M.; Gianella, M.; Vogel, O.; Jirkof, P.; Cesarovic, N.; Klohs, J.; Jakob, P.; Brock, M.; Gorr, T.A.; Baum, O.; Hoppeler, H.; Samillan-Soto, V.; Gassmann, M.; Fischer, J.A.; Born, W.; Vogel, J. (Wiley, 2014)
    Aim: It is unknown how the heart distinguishes various overloads, such as exercise or hypertension, causing either physiological or pathological hypertrophy. We hypothesize that alpha-calcitonin-gene-related peptide (αCGRP), ...
  • Mechanisms of liver fibrosis associated with experimental fasciola hepatica infection: Roles of Fas2 proteinase and hepatic stellate cell activation 
    Marcos, L.A.; Terashima, A.; Yi, P.; Andrade, R.; Cubero, F.J.; Albanis, E.; Gotuzzo Herencia, José Eduardo; Espinoza, J.R.; Friedman, S.L. (American Society of Parasitologists, 2011)
    We have evaluated the possible mechanisms of liver fibrosis caused by Fasciola hepatica in an animal model and in culture using immortalized human stellate cells. Liver biopsies of F. hepatica-infected rats were performed ...
  • Role of metal ions on the activity of Mycobacterium tuberculosis pyrazinamidase 
    Sheen Cortavarria, Patricia; Ferrer, P.; Gilman, Robert Hugh; Christiansen, G.; Moreno-Román, P.; Gutiérrez, A.H.; Sotelo, J.; Evangelista, W.; Fuentes, P.; Rueda, D.; Flores, M.; Olivera, P.; Solis, J.; Pesaresi, A.; Lamba, D.; Zimic-Peralta, Mirko Juan (American Society of Tropical Medicine and Hygiene, 2012)
    Pyrazinamidase of Mycobacterium tuberculosis catalyzes the conversion of pyrazinamide to the active molecule pyrazinoic acid. Reduction of pyrazinamidase activity results in a level of pyrazinamide resistance. Previous ...
  • Store-operated channels in the pulmonary circulation of high- and low-altitude neonatal lambs 
    Parrau, Daniela; Ebensperger, Germán; Herrera, Emilio A.; Moraga, Fernanda; Riquelme, Raquel A.; Ulloa, César E.; Rojas, Rodrigo T.; Silva, Pablo; Hernandez, Ismael; Ferrada, Javiera; Diaz, Marcela; Parer, Julian T.; Cabello, Gertrudis; Llanos, Aníbal J.; Reyes, Roberto V. (American Physiological Society, 2013)
    We determined whether store-operated channels (SOC) are involved in neonatal pulmonary artery function under conditions of acute and chronic hypoxia, using newborn sheep gestated and born either at high altitude (HA, 3,600 ...
  • Strongyloidiasis and Infective Dermatitis Alter Human T Lymphotropic Virus-1 Clonality in vivo 
    Gillet, Nicolas A.; Cook, Lucy; Laydon, Daniel J.; Hlela, Carol; Verdonck, Kristien; Alvarez, Carolina; Gotuzzo Herencia, José Eduardo; Clark, Daniel; Farré, Lourdes; Bittencourt, Achiléa; Asquith, Becca; Taylor, Graham P.; Bangham, Charles R.M. (Public Library of Science, 2013)
    Human T-lymphotropic Virus-1 (HTLV-1) is a retrovirus that persists lifelong by driving clonal proliferation of infected T-cells. HTLV-1 causes a neuroinflammatory disease and adult T-cell leukemia/lymphoma. Strongyloidiasis, ...

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