Listar por tema "leishmaniasis"

Mostrando ítems 1-9 de 9

Association of the Endobiont Double-Stranded RNA Virus LRV1 With Treatment Failure for Human Leishmaniasis Caused by Leishmania braziliensis in Peru and Bolivia

Adaui, Vanessa; Lye, Lon-Fye; Akopyants, Natalia S.; Zimic-Peralta, Mirko Juan; Llanos Cuentas, Elmer Alejandro; Garcia, Lineth; Maes, Ilse; De Doncker, Simonne; Dobson, Deborah E.; Arévalo Zelada, Jorge Luis; Dujardin, Jean-Claude; Beverley, Stephen M. (Oxford University Press, 2015)

Cutaneous and mucosal leishmaniasis, caused in South America by Leishmania braziliensis, is difficult to cure by chemotherapy (primarily pentavalent antimonials [Sb(V)]). Treatment failure does not correlate well with ...
The catalytic role of a research university and international partnerships in building research capacity in Peru: A bibliometric analysis.

Belter, Christopher W.; Garcia Funegra, Patricia Jannet; Livinski, Alicia A.; León-Velarde, Fabiola; Weymouth, Kristen H.; Glass, Roger I. (Public Library of Science, 2019)

Objective: In Peru, the past three decades have witnessed impressive growth in biomedical research catalyzed from a single research university and its investigators who secured international partnerships and funding. We ...
Characterization of Leishmania species from Peru

Romero, G.G.; Arana, Margarita; López, Martin; Montoya, I.; Bohl, R.; Campos Sanchez, Miguel; Arévalo Zelada, Jorge Luis; Llanos Cuentas, Elmer Alejandro (Oxford University Press, 1987)

Twenty-six isolates of Leishmania parasites of Peruvian origin were studied by isoenzyme electrophoresis of four marker enzymes (ASAT, ALAT, G6PD and GPI), kinetoplast DNA hybridization and monoclonal antibody binding and ...
DNA thermodynamic pressure: A potential contributor to genome evolution

Zimic-Peralta, Mirko Juan; Guerra Giraldez, Daniel; Arévalo Zelada, Jorge Luis (Oxford University Press, 2002)

Codon usage bias is a feature of living organisms. The origin of this bias might be explained not only by external factors but also by the nature of the structure of deoxyribonucleic acid (DNA) itself. We have developed a ...
A FRET-Based Real-Time PCR Assay to Identify the Main Causal Agents of New World Tegumentary Leishmaniasis

Tsukayama Cisneros, Pablo; Núñez, Jorge H.; De Los Santos, Maxy; Soberón, Valeria; Lucas, Carmen M.; Matlashewski, Greg; Llanos Cuentas, Elmer Alejandro; Ore, Marianela; Baldeviano, G.Christian; Edgel, Kimberly A.; Lescano Guevara, Andres Guillermo; Graf, Paul C.F.; Bacon, David J. (Public Library of Science, 2013)

In South America, various species of Leishmania are endemic and cause New World tegumentary leishmaniasis (NWTL). The correct identification of these species is critical for adequate clinical management and surveillance ...
Influence of Leishmania RNA Virus 1 on Proinflammatory Biomarker Expression in a Human Macrophage Model of American Tegumentary Leishmaniasis

Kariyawasam, R.; Grewal, J.; Lau, R.; Purssell, A.; Valencia, B. M.; Llanos Cuentas, Elmer Alejandro; Boggild, A. K. (Oxford University Press, 2017)

Backgound. Species of the Leishmania Viannia (L. V.) subgenus harbor the double-stranded Leishmania RNA virus 1 (LRV-1), previously identified in isolates from Brazil and Peru. Higher levels of LRV-1 in metastasizing strains ...
Molecular epidemiology and diagnosis of Leishmania: What have we learnt from genome structure and function?

Dujardin, J.; Victoir, K.; De Doncker, S.; Guerbouj, S.; Arévalo Zelada, Jorge Luis; Le Ray, D. (Oxford University Press, 2002)

This paper reviews our exploration of the dynamics of the Leishmania genome and its contribution to epidemiology and diagnosis. We used as a model Peruvian populations of L. (Viannia) braziliensis and L. (V.) peruviana, 2 ...
Non-invasive cytology brush pcr diagnostic testing in mucosal leishmaniasis: Superior performance to conventional biopsy with histopathology

Boggild, A.K.; Valencia, B.M.; Veland, N.; Ramos, A.P.; Calderon, F.; Arévalo Zelada, Jorge Luis; Low, D.E.; Llanos Cuentas, Elmer Alejandro (Public Library of Science, 2011)

Background: Traditional methods of diagnosing mucosal leishmaniasis (ML), such as biopsy with histopathology, are insensitive and require collection of an invasive diagnostic specimen. Methods: We compared standard invasive ...
Virulence factor RNA transcript expression in the Leishmania Viannia subgenus: Influence of species, isolate source, and Leishmania RNA virus-1

Kariyawasam, R.; Mukkala, A.N.; Lau, R.; Valencia, B.M.; Llanos Cuentas, Elmer Alejandro; Boggild, A.K. (Springer, 2019)

Background: Leishmania RNA virus-1 (LRV1) is a double-stranded RNA virus identified in 20-25% of Viannia - species endemic to Latin America, and is believed to accelerate cutaneous to mucosal leishmaniasis over time. Our ...

Listar por tema "leishmaniasis"

Listar por tema "leishmaniasis"

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