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Browsing by Subject "multicenter study"

Browsing by Subject "multicenter study"

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  • Aspirin in patients undergoing noncardiac surgery 
    Devereaux, P.J.; Mrkobrada, M.; Sessler, D.I.; Leslie, K.; Alonso-Coello, P.; Kurz, A.; Villar, J.C.; Sigamani, A.; Biccard, B.M.; Meyhoff, C.S.; Parlow, J.L.; Guyatt, G.; Robinson, A.; Garg, A.X.; Rodseth, R.N.; Botto, F.; Lurati Buse, G.; Xavier, D.; Chan, M.T.V.; Tiboni, M.; Cook, D.; Kumar, P.A.; Forget, P.; Málaga Rodríguez, Germán Javier; Fleischmann, E.; Amir, M.; Eikelboom, J.; Mizera, R.; Torres, D.; Wang, C.Y.; VanHelder, T.; Paniagua, P.; Berwanger, O.; Srinathan, S.; Graham, M.; Pasin, L.; Le Manach, Y.; Gao, P.; Pogue, J.; Whitlock, R.; Lamy, A.; Kearon, C.; Baigent, C.; Chow, C.; Pettit, S.; Chrolavicius, S.; Yusuf, S. (Massachusetts Medical Society, 2014)
    BACKGROUND: There is substantial variability in the perioperative administration of aspirin in patients undergoing noncardiac surgery, both among patients who are already on an aspirin regimen and among those who are not. ...
  • Biomarkers of fluoride in children exposed to different sources of systemic fluoride 
    Buzalaf, M.A.R.; Rodrigues, M.H.C.; Pessan, J.P.; Leite, A.L.; Arana, A.; Villena, R.S.; Forte, F.D.S.; Sampaio, F.C. (SAGE Publications, 2011)
    There has been no comparison between fluoride concentrations in urine and nails of children exposed to different sources of systemic fluoride. The aim of this study was to compare the relationship between fluoride intake ...
  • Case report: Histopathological features of tungiasis in Peru 
    Maco, Vicente; Maco, Vicente P.; Tantalean, Manuel E.; Gotuzzo Herencia, José Eduardo (American Society of Tropical Medicine and Hygiene, 2013)
    Tungiasis is an ectoparasitic skin disease caused byTunga penetransandTunga trimamillata. There is a lackof histopathological studies that evaluate the recognition of this flea in tissues. We describe theex vivodermoscopic ...
  • Clonidine in patients undergoing noncardiac surgery 
    Devereaux, P.J.; Sessler, D.I.; Leslie, K.; Kurz, A.; Mrkobrada, M.; Alonso-Coello, P.; Villar, J.C.; Sigamani, A.; Biccard, B.M.; Meyhoff, C.S.; Parlow, J.L.; Guyatt, G.; Robinson, A.; Garg, A.X.; Rodseth, R.N.; Botto, F.; Lurati Buse, G.; Xavier, D.; Chan, M.T.V.; Tiboni, M.; Cook, D.; Kumar, P.A.; Forget, P.; Málaga Rodríguez, Germán Javier; Fleischmann, E.; Amir, M.; Eikelboom, J.; Mizera, R.; Torres, D.; Wang, C.Y.; VanHelder, T.; Paniagua, P.; Berwanger, O.; Srinathan, S.; Graham, M.; Pasin, L.; Le Manach, Y.; Gao, P.; Pogue, J.; Whitlock, R.; Lamy, A.; Kearon, C.; Chow, C.; Pettit, S.; Chrolavicius, S.; Yusuf, S. (Massachusetts Medical Society, 2014)
    BACKGROUND: Marked activation of the sympathetic nervous system occurs during and after non-cardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may prevent perioperative myocardial infarction and ...
  • Combined predictors of neurodevelopment in very low birth weight preterm infants 
    Medina-Alva, Pilar; Duque, Kevin R.; Zea-Vera, Alonso; Bellomo, Sicilia; Cárcamo Cavagnaro, César Paul Eugenio; Guillén Pinto, Daniel; Rivas, Maria; Tori, Alfredo; Zegarra, Jaime; Cam, Luis; Castañeda, Anne; Villavicencio, Aasith; Ochoa Woodell, Theresa Jean (Elsevier, 2019)
    Objective: To evaluate the combined prognostic value of neurological examination, head circumference and cranial ultrasound for neurodevelopmental delay (NDD) in very low birth weight (VLBW, <1500 g) preterm infants. ...
  • Disección endoscópica de submucosa para neoplasias gástricas superficiales en dos hospitales de referencia en Brasil: ¿se pueden igualar los resultados de Japón y Corea del Sur? 
    Arantes, V.; Aliaga Ramos, J.; Pedrosa, M.S. (Elsevier, 2021)
    Introduction and aims: Endoscopic submucosal dissection (ESD) in the treatment of superficial neoplasias of the gastrointestinal tract is currently one of the greatest advances in therapeutic endoscopy. Due to its high ...
  • Efficacy and tolerability of two single-day regimens of triclabendazole for fascioliasis in Peruvian children 
    Maco, V.; Marcos, L.; Delgado, J.; Herrera, J.; Nestares, J.; Terashima, A.; Samalvides Cuba, Frine; Gotuzzo Herencia, José Eduardo (Sociedade Brasileira de Medicina Tropical, 2015)
    Introduction: The therapeutic scheme of triclabendazole (TCBZ), the recommended anthelmintic against Fasciola hepatica, involves 10mg/kg of body weight administered in a single dose; however, clinical trials in children ...
  • Global REACH 2018: High Blood Viscosity and Hemoglobin Concentration Contribute to Reduced Flow-Mediated Dilation in High-Altitude Excessive Erythrocytosis 
    Tremblay, Joshua C.; Hoiland, Ryan L.; Howe, Connor A.; Coombs, Geoff B.; Vizcardo-Galindo, Gustavo A.; Figueroa-Mujica, Romulo J.; Bermudez, Daniela; Gibbons, Travis D.; Stacey, Benjamin S.; Bailey, Damian M.; Tymko, Michael M.; MacLeod, David B.; Gasho, Chris; Villafuerte, Francisco C.; Pyke, Kyra E.; Ainslie, Philip N. (Wolters Kluwer Health, 2019)
    Excessive erythrocytosis (EE; hemoglobin concentration [Hb] >/=21 g/dL in adult males) is associated with increased cardiovascular risk in highlander Andeans. We sought to quantify shear stress and assess endothelial ...
  • Incidence of virological failure and major regimen change of initial combination antiretroviral therapy in the Latin America and the Caribbean: An observational cohort study 
    Cesar, C.; Jenkins, C.A.; Shepherd, B.E.; Padgett, D.; Mejía Cordero, Fernando Alonso; Ribeiro, S.R.; Cortes, C.P.; Pape, J.W.; Sierra Madero, J.; Fink, V.; Sued, O.; McGowan, C.; Cahn, P.; Grinsztejn, B.; Reyes, M.W.; Gotuzzo Herencia, José Eduardo; CCASAnet (Elsevier, 2015)
    Background: Access to combination antiretroviral therapy (ART) is expanding in Latin America (Mexico, Central America, and South America) and the Caribbean. We assessed the incidence of and factors associated with regimen ...
  • Knowledge, attitudes and practice survey about antimicrobial resistance and prescribing among physicians in a hospital setting in Lima, Peru 
    García Apac, Coralith Marlinda; Llamocca, L.P.; García, K.; Jiménez, A.; Samalvides Cuba, Frine; Gotuzzo Herencia, José Eduardo; Jacobs, J. (BioMed Central, 2011)
    Background: Misuse of antimicrobials (AMs) and antimicrobial resistance (AMR) are global concerns. The present study evaluated knowledge, attitudes and practices about AMR and AM prescribing among medical doctors in two ...
  • Long-Term Efficacy and Safety of Biosimilar CT-P10 Versus Innovator Rituximab in Rheumatoid Arthritis: 48-Week Results from a Randomized Phase III Trial 
    Suh, Chang-Hee; Yoo, Dae Hyun; Berrocal Kasay, Alfredo; Chalouhi El-Khouri, Elia; Cons Molina, Francisco Fidenci; Shesternya, Pavel; Miranda, Pedro; Medina-Rodriguez, Francisco G.; Wiland, Piotr; Jeka, Slawomir; Chavez-Corrales, Jose; Linde, Thomas; Hrycaj, Pawel; Abello-Banfi, Mauricio; Hospodarskyy, Ihor; Jaworski, Janusz; Piotrowski, Mariusz; Brzosko, Marek; Krogulec, Marek; Shevchuk, Sergii; Calvo, Armando; Andersone, Daina; Park, Won; Shim, Seung Cheol; Lee, Sang Joon; Lee, Sung Young (Springer, 2019)
    Objective: The aim of this study was to investigate long-term clinical outcomes of extended treatment with CT-P10, a rituximab biosimilar, compared with rituximab reference products sourced from the USA and the EU (US-RTX ...
  • Multidrug-resistant tuberculosis and culture conversion with bedaquiline 
    Diacon, Andreas H.; Pym, Alexander; Grobusch, Martin P.; De Los Rios, Jorge M.; Gotuzzo Herencia, José Eduardo; Vasilyeva, Irina; Leimane, Vaira; Andries, Koen; Bakare, Nyasha; De Marez, Tine; Haxaire-Theeuwes, Myriam; Lounis, Nacer; Meyvisch, Paul; De Paepe, Els; Van Heeswijk, Rolf P.G.; Dannemann, Brian (Massachusetts Medical Society, 2014)
    BACKGROUND: Bedaquiline (Sirturo, TMC207), a diarylquinoline that inhibits mycobacterial ATP synthase, has been associated with accelerated sputum-culture conversion in patients with multidrug-resistant tuberculosis, when ...
  • Mycobacterium tuberculosis-specific cytokine biomarkers for the diagnosis of childhood TB in a TB-endemic setting 
    Sudbury, Eva L.; Otero Vegas, Larissa; Tebruegge, Marc; Messina, Nicole L.; Seas Ramos, Carlos Rafael; Montes Delgado, Martin; Rios, Julia; Germano, Susie; Gardiner, Kaya; Clifford, Vanessa; Gotuzzo Herencia, José Eduardo; Curtis, Nigel (Elsevier, 2019)
    The tuberculin skin test and interferon-gamma release assays have limitations in diagnosing tuberculosis (TB), particularly in children. This study investigated the performance of candidate M. tuberculosis-specific cytokine ...
  • Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study 
    García Castaño, A.; Pérez de Nanclares, G.; Madariaga, L.; Aguirre, M.; Chocron, S.; Madrid, A.; Lafita Tejedor, F.J.; Gil Campos, M.; Sánchez del Pozo, J.; Ruiz Cano, R.; Espino, M.; Gomez Vida, J.M.; Santos, F.; García Nieto, V.M.; Loza, R.; Rodríguez, L.M.; Hidalgo Barquero, E.; Printza, N.; Camacho, J.A.; Castaño, L.; Ariceta, G.; RenalTube Group (Springer, 2015)
    Molecular diagnosis is a useful diagnostic tool in primary nephrogenic diabetes insipidus (NDI), an inherited disease characterized by renal inability to concentrate urine. The AVPR2 and AQP2 genes were screened for mutations ...
  • Patient perspectives on the promptness and quality of care of road traffic incident victims in Peru: A cross-sectional, active surveillance study 
    Miranda, J. Jaime; Rosales-Mayor, Edmundo; Quistberg, D. Alex; Paca-Palao, Ada; Gianella, Camila; Perel, Pablo; Lopez, Luis; Luna, Diego; Best, Pablo; Huicho Oriundo, Luis (F1000 Research, 2013)
    Background: Road injuries are the second-leading cause of disease and injury in the Andean region of South America. Adequate management of road traffic crash victims is important to prevent and reduce deaths and serious ...
  • Provider attitudes towards a brief behavioral intervention for sexual health in Moldova 
    Stephenson, R.; Lesco, G.; Babii, V.; Luchian, A.; Bakunina, N.; De Vasconcelos, A.S.; Blondeel, K.; Caceres Palacios, Carlos Fernando; Pitter, R.A.; Metheny, N.; Goldenberg, T.; Kiarie, J.; Toskin, I. (BioMed Central, 2021)
    Background: Brief behavioral interventions are seen as an efficient way to improve knowledge, change behavior, and reduce provider stigma regarding sexual health. When grounded in evidence-based behavioral change techniques ...
  • Randomized trial of early bubble continuous positive airway pressure for very low birth weight infants 
    Tapia, J.L.; Urzua, S.; Bancalari, A.; Meritano, J.; Torres, G.; Fabres, J.; Toro, C.A.; Rivera, F.; Cespedes, E.; Burgos, J.F.; Mariani, G.; Roldan, L.; Silvera, F.; Gonzalez, Agustina; Dominguez, A. (Elsevier, 2012)
    Objective: To determine whether very low birth weight infants (VLBWIs), initially supported with continuous positive airway pressure (CPAP) and then selectively treated with the INSURE (intubation, surfactant, and extubation ...
  • Remission and low disease activity state (LDAS) are protective of intermediate and long-term outcomes in SLE patients. Results from LUMINA (LXXVIII), a multiethnic, multicenter US cohort 
    Alarcón, Graciela S.; Ugarte Gil, Manuel Francisco; Pons-Estel, G.; Vilá, L.M.; Reveille, J.D.; McGwin, G., Jr. (SAGE Publications, 2019)
    Objective: The objective of this report is to determine the impact of remission and low disease activity state (LDAS) on damage accrual and mortality in systemic lupus erythematosus (SLE) patients. Patients and methods: ...
  • Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results 
    Pan, Hongchao; Peto, Richard; Henao-Restrepo, Ana-Maria; Preziosi, Marie-Pierre; Sathiyamoorthy, Vasee; Abdool Karim, Quarraisha; Alejandria, Marissa M.; Hernández García, César; Kieny, Marie-Paule; Malekzadeh, Reza; Murthy, Srinivas; Reddy, K. Srinath; Roses Periago, Mirta; Abi Hanna, Pierre; Ader, Florence; Al-Bader, Abdullah M.; Alhasawi, Almonther; Allum, Emma; Alotaibi, Athari; Alvarez-Moreno, Carlos A.; Appadoo, Sheila; Asiri, Abdullah; Aukrust, Pål; Barratt-Due, Andreas; Bellani, Samir; Branca, Mattia; Cappel-Porter, Heike B. C.; Cerrato, Nery; Chow, Ting S.; Como, Najada; Eustace, Joe; Garcia Funegra, Patricia Jannet; Godbole, Sheela; Gotuzzo Herencia, José Eduardo; Griskevicius, Laimonas; Hamra, Rasha; Hassan, Mariam; Hassany, Mohamed; Hutton, David; Irmansyah, Irmansyah; Jancoriene, Ligita; Kirwan, Jana; Kumar, Suresh; Lennon, Peter; Lopardo, Gustavo; Lydon, Patrick; Magrini, Nicola; Maguire, Teresa; Manevska, Suzana; Manuel, Oriol; McGinty, Sibylle; Medina, Marco T.; Mesa Rubio, María L.; Miranda-Montoya, Maria C.; Nel, Jeremy; Nunes, Estevao P.; Perola, Markus; Portolés, Antonio; Rasmin, Menaldi R.; Raza, Aun; Rees, Helen; Reges, Paula P. S.; Rogers, Chris A.; Salami, Kolawole; Salvadori, Marina I.; Sinani, Narvina; Sterne, Jonathan A. C.; Stevanovikj, Milena; Tacconelli, Evelina; Tikkinen, Kari A. O.; Trelle, Sven; Zaid, Hala; Røttingen, John-Arne; Swaminathan, Soumya (Massachusetts Medical Society, 2020)
    BACKGROUND: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs - remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a - in patients hospitalized with ...
  • Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort 
    Aragon, Romina E.; Proano, Alvaro; Mongilardi, Nicole; de Ferrari, Aldo; Herrera, Phabiola; Roldan, Rollin; Paz, Enrique; Jaymez, Amador A.; Chirinos, Eduardo; Portugal, Jose; Quispe, Rocio; Brower, Roy G.; Checkley, William (BioMed Central, 2019)
    OBJECTIVES: We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting. DESIGN: A longitudinal study of ...

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