Listar por tema "multiple sclerosis"

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  • Biological and nonbiological complex drugs for multiple sclerosis in Latin America: Regulations and risk management 
    Carrá, A.; Macías Islas, M.A.; Tarulla, A.; Bichuetti, D.B.; Finkelsztejn, A.; Dadalti Fragoso, Y.; Árcega-Revilla, R.; Cárcamo Rodríguez, C.; Durán, J.C.; García Bonitto, J.; León, Rosalba; Oehninger Gatti, C.; Orozco, G.; Vizcarra-Escobar, Darwin (Taylor and Francis, 2015)
    Biological drugs and nonbiological complex drugs with expired patents are followed by biosimilars and follow-on drugs that are supposedly similar and comparable with the reference product in terms of quality, safety and ...
  • CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis 
    Menezes, Soraya Maria; Decanine, Daniele; Brassat, David; Khouri, Ricardo; Schnitman, Saul V.; Kruschewsky, Ramon; López, Giovanni; Alvarez, Carolina; Talledo Albujar, Michael John; Gotuzzo Herencia, José Eduardo; Vandamme, Anne-Mieke; Galvão-Castro, Bernardo; Liblau, Roland; Weyenbergh, Johan Van (BioMed Central, 2014)
    Background: Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no ...
  • A Fas(hi) Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation 
    Menezes, Soraya Maria; Leal, Fabio E.; Dierckx, Tim; Khouri, Ricardo; Decanine, Daniele; Silva-Santos, Gilvaneia; Schnitman, Saul V.; Kruschewsky, Ramon; Lopez, Giovanni; Alvarez, Carolina; Talledo Albujar, Michael John; Gotuzzo Herencia, José Eduardo; Nixon, Douglas F.; Vercauteren, Jurgen; Brassat, David; Liblau, Roland; Vandamme, Anne Mieke; Galvao-Castro, Bernardo; Van Weyenbergh, Johan (Frontiers Media, 2017)
    Human T-cell lymphotropic virus (HTLV)-1 was the first human retrovirus to be associated to cancer, namely adult T-cell leukemia (ATL), but its pathogenesis remains enigmatic, since only a minority of infected individuals ...
  • Latitudinal prevalence gradient of multiple sclerosis in Latin America 
    Risco, J.; Maldonado, H.; Luna, L.; Osada, J.; Ruiz, P.; Juarez, A.; Vizcarra-Escobar, Darwin (SAGE Publications, 2011)
    Background: Multiple sclerosis (MS) has a unique geographical distribution that reflects both genetic and environmental factors. Many studies have shown a positive correlation between MS frequency and latitude across both ...
  • Optimizing outcomes in multiple sclerosis: Consensus guidelines for the diagnosis and treatment of multiple sclerosis in Latin America 
    Carra, A.; Macías Islas, M.A.; Gabbai, A.A.; Correale, J.; Bolana, C.; Sotelo, E.D.; Bonitto, J.G.; Vergara Edwards, F.; Vizcarra-Escobar, Darwin (SAGE Publications, 2011)
    Objective: The prevalence of multiple sclerosis (MS) in Latin America varies across different studies but an intermediate risk and increased frequency of the disease have been reported in recent years. The circumstances ...
  • Practical Issues Concerning the Approval and Use of Biosimilar Drugs for the Treatment of Multiple Sclerosis in Latin America 
    Steinberg, Judith; Fragoso, Yara D.; Duran Quiroz, Juan Carlos; Garcia, Juan Raul; Guerra, Caroline; Rodriguez, Virginia; Carcamo Rodriguez, Claudia; Ciampi, Ethel; Correa-Diaz, Edgar; Macias, Miguel; Novarro, Nelson; Vizcarra-Escobar, Darwin; Oehninger Gatti, Carlos; Orozco, Geraldine; Carra, Adriana (Springer, 2019)
    The use of biosimilar drugs for multiple sclerosis (MS) has become widespread in Latin America, with the goal of reducing costs of treatments, promoting the sustainability of healthcare systems, and improving patient ...
  • Treatment issues in multiple sclerosis in Latin America 
    Vizcarra-Escobar, Darwin; Mendiola-Yamasato, A.; Anculle-Arauco, V.; Vizcarra-Pasapera, J.; Guillen-Mendoza, Daniel (Karger, 2015)
    Treatment issues of multiple sclerosis (MS) in Latin America (LA) have recently been addressed. Some particular features of the health systems, patients and medical providers are scarcely described. Moreover, LA patients ...

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