Listar por tema "tuberculosis"

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  • Active and passive case-finding in tuberculosis-affected households in Peru: a 10-year prospective cohort study 
    Saunders, Matthew J.; Tovar, Marco A.; Collier, Dami; Baldwin, Matthew R.; Montoya, Rosario; Valencia, Teresa R.; Gilman, Robert Hugh; Evans, Carlton Anthony William (Elsevier, 2019)
    Background: Active case-finding among contacts of patients with tuberculosis is a global health priority, but the effects of active versus passive case-finding are poorly characterised. We assessed the contribution of ...
  • Algorithm for the diagnosis of smear-negative pulmonary tuberculosis in high-incidence resource-constrained settings 
    Soto, Alonso; Solari, Lely; Agapito, Juan; Gotuzzo Herencia, José Eduardo; Accinelli Tanaka, Roberto Alfonso; Vargas, Dante; Acurio, Vilma; Matthys, Francine; Van der Stuyft, Patrick (Wiley, 2013)
    Objectives: Diagnosis of smear-negative pulmonary tuberculosis (SNPT) remains a challenge, particularly in resource-constrained settings. We evaluated a diagnostic algorithm that combines affordable laboratory tools and a ...
  • Alternative cost-effective media to facilitate MODS culture for diagnostics of tuberculosis 
    Sheen Cortavarria, Patricia; Rodriguez, Joseline; Alcantara, Roberto; Vargas, Johnny; Grandjean, Louis; Moore, David Alexander James; Gilman, Robert Hugh; Zimic-Peralta, Mirko Juan (Elsevier, 2022)
    Most culture-based methods for tuberculosis diagnosis remain low-cost options for low- and mid-income countries. The MODS culture is a rapid and low-cost assay to diagnose tuberculosis and determine drug susceptibility. ...
  • Automatic diagnostics of tuberculosis using convolutional neural networks analysis of MODS digital images 
    Lopez-Garnier, Santiago; Sheen Cortavarria, Patricia; Zimic-Peralta, Mirko Juan (Public Library of Science, 2019)
    Tuberculosis is an infectious disease that causes ill health and death in millions of people each year worldwide. Timely diagnosis and treatment is key to full patient recovery. The Microscopic Observed Drug Susceptibility ...
  • Bioimpedance markers and tuberculosis outcome among HIV-infected patients 
    Montalvo, Raúl; Bernabé Ortiz, Antonio; Kirwan, Daniela E.; Gilman, Robert Hugh (African Traditional Herbal Medicine Supporters Initiative, 2018)
    Background: The changes in body composition markers (weight, fat mass, lean mass, and BMI) over time can be associated with TB treatment outcome among HIV-infected patients. The aim of this study was to investigate whether ...
  • A case control study to identify community venues associated with genetically clustered Multidrug-resistant Tuberculosis disease in Lima, Peru 
    Bui, David P.; Oren, Eyal; Roe, Denise J.; Brown, Heidi E.; Harris, Robin B.; Knight, Gwenan M.; Gilman, Robert Hugh; Grandjean, Louis (Oxford University Press, 2018)
    Background: The majority of tuberculosis transmission occurs in community settings. The primary aim of this study was to assess the association between exposure to community venues and multidrug-resistant tuberculosis ...
  • The catalytic role of a research university and international partnerships in building research capacity in Peru: A bibliometric analysis. 
    Belter, Christopher W.; Garcia Funegra, Patricia Jannet; Livinski, Alicia A.; León-Velarde, Fabiola; Weymouth, Kristen H.; Glass, Roger I. (Public Library of Science, 2019)
    Objective: In Peru, the past three decades have witnessed impressive growth in biomedical research catalyzed from a single research university and its investigators who secured international partnerships and funding. We ...
  • Clinical standards for the assessment, management and rehabilitation of post-TB lung disease 
    Migliori, G.B.; Marx, F.M.; Ambrosino, N.; Zampogna, E.; Schaaf, H.S.; van der Zalm, M.M.; Allwood, B.; Byrne, A.L.; Mortimer, K.; Wallis, R.S.; Fox, G.J.; Leung, C.C.; Chakaya, J.M.; Seaworth, B.; Rachow, A.; Marais, B.J.; Furin, J.; Akkerman, O.W.; Al Yaquobi, F.; Amaral, A.F.S.; Borisov, S.; Caminero, J.A.; Carvalho, A.C.C.; Chesov, D.; Codecasa, L.R.; Teixeira, R.C.; Dalcolmo, M.P.; Datta, S.; Dinh-Xuan, A.-T.; Duarte, R.; Evans, Carlton Anthony William; García-García, J.-M.; Günther, G.; Hoddinott, G.; Huddart, S.; Ivanova, O.; Laniado-Laborín, R.; Manga, S.; Manika, K.; Mariandyshev, A.; Mello, F.C.Q.; Mpagama, S.G.; Muñoz-Torrico, M.; Nahid, P.; Ong, C.W.M.; Palmero, D.J.; Piubello, A.; Pontali, E.; Silva, D.R.; Singla, R.; Spanevello, A.; Tiberi, S.; Udwadia, Z.F.; Vitacca, M.; Centis, R.; D'Ambrosio, L.; Sotgiu, G.; Lange, C.; Visca, D. (International Union Against Tuberculosis and Lung Disease, 2021)
    BACKGROUND: Increasing evidence suggests that post-TB lung disease (PTLD) causes significant morbidity and mortality. The aim of these clinical standards is to provide guidance on the assessment and management of PTLD and ...
  • Clinical, radiological and functional characteristics of pulmonary diseases among htlv-1 infected patients without prior active tuberculosis infection 
    Cachay Figueroa, Rodrigo Antonio; Gil-Zacarias, M.; Watanabe-Tejada, T.; Schwalb Calderon, Alvaro; Mejía Cordero, Fernando Alonso; Gayoso, O.; Gotuzzo Herencia, José Eduardo (MDPI, 2021)
    The lifelong infection with the human T lymphotropic virus type 1 (HTLV-1) has been associated with a variety of clinical manifestations; one of the less-explored is HTLV-1-associated pulmonary disease. Imaging of lung ...
  • Conformational Response of 30S-bound IF3 to A-Site Binders Streptomycin and Kanamycin 
    Chulluncuy, Roberto; Espiche, Carlos; Nakamoto, Jose-Alberto; Fabbretti, Attilio; Milon, Pohl (MDPI, 2016)
    Aminoglycoside antibiotics are widely used to treat infectious diseases. Among them, streptomycin and kanamycin (and derivatives) are of importance to battle multidrug-resistant (MDR) Mycobacterium tuberculosis. Both drugs ...
  • Conocimiento y actitudes sobre tuberculosis en pacientes pertenecientes al programa de control de la tuberculosis de San Juan de Lurigancho, Lima-Perú 
    Seas Ramos, Carlos Rafael; Zamudio Fuertes, Carlos Eduardo; Calderón Arizmendi, María Laura; Calderón Arizmendi, María Laura; Shah, Lena; Gonzales-Lago, Elsa; Pérez Dávila, Luis Andrés; Robledo Lock, Jorge Luis (Universidad Peruana Cayetano Heredia, 2017)
    Introducción: La tuberculosis (TB) continúa siendo un problema para la salud pública en el Perú. Las deficiencias en el conocimiento de la enfermedad, barreras culturales y prácticas de la sociedad influyen en el control ...
  • Contact evaluation and isoniazid preventive therapy among close and household contacts of tuberculosis patients in Lima, Peru: an analysis of routine data. 
    Otero Vegas, Larissa; Battaglioli, Tullia; Rios, Julia; De la Torre, Zayda; Trocones, Nayda; Ordonez, Cielo; Seas Ramos, Carlos Rafael; Van der Stuyft, Patrick (Wiley, 2019)
    OBJECTIVE: Contacts of pulmonary tuberculosis (TB) cases are at high risk of TB infection and progression to disease. Close and household contacts and those <5 years old have the highest risk. Isoniazid preventive therapy ...
  • The contribution of late HIV diagnosis on the occurrence of HIV-associated tuberculosis 
    Girardi, Enrico; Caro-Vega, Yanink; Cozzi-Lepri, Alessandro; Musaazi, Joseph; Carriquiry, Gabriela; Castelnuovo, Barbara; Gori, Andrea; Manabe, Yukari C.; Gotuzzo Herencia, José Eduardo; D'arminio Monforte, Antonella; Crabtree-Ramirez, Brenda; Mussini, Cristina (Wolters Kluwer Health, 2022)
    OBJECTIVES: To describe the timing of tuberculosis (TB) presentation in relation to diagnosis of HIV infection and antiretroviral therapy (ART) initiation and to evaluate whether the established impact from late presentation ...
  • Cough Frequency During Treatment Associated With Baseline Cavitary Volume and Proximity to the Airway in Pulmonary TB 
    Proaño, Alvaro; Bui, David P.; López, José W.; Vu, Nancy M.; Bravard, Marjory A.; Lee, Gwenyth O.; Tracey, Brian H.; Xu, Ziyue; Comina, Germán; Ticona, Eduardo; Mollura, Daniel J.; Friedland, Jon S.; Moore, David Alexander James; Evans, Carlton Anthony William; Caligiuri, Philip; Gilman, Robert Hugh (Elsevier, 2018)
    BACKGROUND: Cough frequency, and its duration, is a biomarker that can be used in low-resource settings without the need of laboratory culture and has been associated with transmission and treatment response. Radiologic ...
  • Cutaneous Mycobacterial Infections 
    Franco-Paredes, Carlos; Marcos, Luis A.; Henao-Martínez, Andrés F.; Rodríguez-Morales, Alfonso J.; Villamil-Gómez, Wilmer E.; Gotuzzo Herencia, José Eduardo; Bonifaz, Alexandro (American Society for Microbiology, 2018)
    Humans encounter mycobacterial species due to their ubiquity in different environmental niches. In many individuals, pathogenic mycobacterial species may breach our first-line barrier defenses of the innate immune system ...
  • Development of an automated MODS plate reader to detect early growth of Mycobacterium tuberculosis 
    Comina, G.; Mendoza, D.; Velazco, A.; Coronel, J.; Sheen Cortavarria, Patricia; Gilman, Robert Hugh; Moore, David Alexander James; Zimic-Peralta, Mirko Juan (Wiley, 2011)
    In this work, an automated microscopic observation drug susceptibility (MODS) plate reader has been developed. The reader automatically handles MODS plates and after autofocussing digital images are acquired of the ...
  • Direct determination of pyrazinamide (PZA) susceptibility by sputum microscopic observation drug susceptibility (MODS) culture at neutral pH: the MODS-PZA assay 
    Alcántara, Roberto; Fuentes, Patricia; Marin, Lisette; Kirwan, Daniela E.; Gilman, Robert Hugh; Zimic-Peralta, Mirko Juan; Sheen Cortavarria, Patricia (American Society for Microbiology, 2020)
    Pyrazinamide (PZA) is considered the pivot drug in all tuberculosis treatment regimens, due to its particular action on the persistent forms of Mycobacterium tuberculosis. However, no drug susceptibility test (DST) is ...
  • Diseases masking and delaying the diagnosis of urogenital tuberculosis 
    Altez-Fernandez, Carlos; Seas Ramos, Carlos Rafael; Zegarra, Luis; Ugarte Gil, Cesar Augusto (SAGE Publications, 2016)
    We read with interest the article by Kulchavenya and Kholtobin on urogenital tuberculosis (UGTB) [Kulchavenya and Kholtobin, 2015], in which the authors provide information about unusual UGTB cases. While the authors claim ...
  • Drug susceptibility testing and mortality in patients treated for tuberculosis in high-burden countries: a multicentre cohort study 
    Zürcher, K.; Ballif, M.; Fenner, L.; Borrell, S.; Keller, P.M.; Gnokoro, J.; Marcy, O.; Yotebieng, M.; Diero, L.; Carter, E.J.; Rockwood, N.; Wilkinson, R.J.; Cox, H.; Ezati, N.; Abimiku, A.G.; Collantes, J.; Avihingsanon, A.; Kawkitinarong, K.; Reinhard, M.; Hömke, R.; Huebner, R.; Gagneux, S.; Böttger, E.C.; Egger, M.; Chammartin, F.; Boettger, E.C.; Keller, P.; Abimiku, A.; Wenzi, L.; Tabala, M.; Warren, R.; Streicher, E.; Wilkinson, R.J.; Carter, E.J.; Zamudio Fuertes, Carlos Eduardo; Sohn, A.; Petersen, T.; Kasipong, N.; N'Guessan, K.; International epidemiology Databases to Evaluate AIDS (Elsevier, 2019)
    Background: Drug resistance is a challenge for the global control of tuberculosis. We examined mortality in patients with tuberculosis from high-burden countries, according to concordance or discordance of results from ...
  • Duration of Anti-Tuberculosis Therapy and Timing of Antiretroviral Therapy Initiation: Association with Mortality in HIV-Related Tuberculosis 
    Cortes, Claudia P.; Wehbe, Firas H.; McGowan, Catherine C.; Shepherd, Bryan E.; Duda, Stephany N.; Jenkins, Cathy A.; González Lagos, Elsa Violeta; Carriquiry, Gabriela; Schechter, Mauro; Padgett, Denis; Cesar, Carina; Madero, Juan Sierra; Pape, JeanW.; Masys, D.R.; Sterling, T.R.; Wolff, M.; Arancibia, J.M.; Saavedra, F.; Salinas, C.; Gonzalez, E.; Carriquiry, G.; Mayer, E.; Condorhuaman, P.; Gotuzzo Herencia, José Eduardo; Schechter, M.; Tuboi, S.H.; Padgett, D.; Cesar, C.; Fink, V.; Sued, O.; Cahn, P.; Crabtree, B.; Madero, J.S.; Bacon, M.; Williams, C.; Shepherd, B.E.; Jenkins, C.A.; Duda, S.N.; Masys, D.R.; McGowan, C.C. (Public Library of Science, 2013)
    Background: Antiretroviral therapy (ART) decreases mortality risk in HIV-infected tuberculosis patients, but the effect of the duration of anti-tuberculosis therapy and timing of anti-tuberculosis therapy initiation in ...

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