Listar por tema "vaccine"

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  • Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded, placebo-controlled, phase 2b/3 trial 
    Kremsner, Peter G.; Ahuad Guerrero, Rodolfo Andrés; Arana-Arri, Eunate; Aroca Martinez, Gustavo Jose; Bonten, Marc; Chandler, Reynaldo; Corral, Gonzalo; De Block, Eddie Jan Louis; Ecker, Lucie; Gabor, Julian Justin; Garcia Lopez, Carlos Alberto; Gonzales, Lucy; Granados González, María Angélica; Gorini, Nestor; Grobusch, Martin P.; Hrabar, Adrian D.; Junker, Helga; Kimura, Alan; Lanata, Claudio F.; Lehmann, Clara; Leroux-Roels, Isabel; Mann, Philipp; Martinez-Reséndez, Michel Fernando; Ochoa Woodell, Theresa Jean; Poy, Carlos Alberto; Reyes Fentanes, Maria Jose; Rivera Mejia, Luis Maria; Ruiz Herrera, Vida Veronica; Sáez-Llorens, Xavier; Schönborn-Kellenberger, Oliver; Schunk, Mirjam; Sierra Garcia, Alexandra; Vergara, Itziar; Verstraeten, Thomas; Vico, Marisa; Oostvogels, Lidia (Elsevier, 2021)
    BACKGROUND: Additional safe and efficacious vaccines are needed to control the COVID-19 pandemic. We aimed to analyse the efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate. METHODS: HERALD is a randomised, ...
  • Immunoinformatic analysis of the whole proteome for vaccine design: An application to Clostridium perfringens 
    Soto, L.F.; Romaní, A.C.; Jiménez-Avalos, Gabriel; Silva, Y.; Ordinola-Ramirez, C.M.; Lopez Lapa, R.M.; Requena, D. (Frontiers Media, 2022)
    Clostridium perfringens is a dangerous bacterium and known biological warfare weapon associated with several diseases, whose lethal toxins can produce necrosis in humans. However, there is no safe and fully effective vaccine ...
  • International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact 
    Gladstone, Rebecca A.; Lo, Stephanie W.; Lees, John A.; Croucher, Nicholas J.; van Tonder, Andries J.; Corander, Jukka; Page, Andrew J.; Marttinen, Pekka; Bentley, Leon J.; Ochoa Woodell, Theresa Jean; Ho, Pak Leung; du Plessis, Mignon; Cornick, Jennifer E.; Kwambana-Adams, Brenda; Benisty, Rachel; Nzenze, Susan A.; Madhi, Shabir A.; Hawkins, Paulina A.; Everett, Dean B.; Antonio, Martin; Dagan, Ron; Klugman, Keith P.; von Gottberg, Anne; McGee, Lesley; Breiman, Robert F.; Bentley, Stephen D. (Elsevier, 2019)
    Background: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study ...
  • New vaccines needed for pathogens infecting animals and humans: One Health 
    Gutiérrez, A.H.; Spero, D.M.; Gay, C.; Zimic-Peralta, Mirko Juan; De Groot, A.S. (Taylor and Francis, 2012)
    The field of "One Health" encourages researchers to collaborate across a wide range of disciplines to improve health at the animal-human- ecosystems interface. One Health recognizes the potential of emerging infectious ...
  • Notes on syphilis vaccine development 
    Kojima, Noah; Konda, Kelika A.; Klausner, Jeffrey D. (Frontiers Media, 2022)
    The quest for a syphilis vaccine to provide protection from infection or disease began not long after the isolation of the first Treponema pallidum subspecies pallidum (T. pallidum) strain in 1912. Yet, a practical and ...
  • Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum 
    Haynes, Austin M.; Fernandez, Mark; Romeis, Emily; Mitjà, Oriol; Konda, Kelika A.; Vargas Rivera, Silver Keith; Eguiluz, Maria; Caceres Palacios, Carlos Fernando; Klausner, Jeffrey D.; Giacani, Lorenzo (Public Library of Science, 2021)
    BACKGROUND: An effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis. Although the combination ...
  • Varicella epidemiology in Latin America and the Caribbean 
    Ávila-Agüero, Maria L.; Beltrán, Sandra; Castillo, José Brea Del; Castillo Díaz, María Esther; Chaparro, Luis Eduardo; Deseda, Carmen; Debbag, Roberto; Espinal, Carlos; Falleiros-Arlant, Luiza Helena; González Mata, Antonio José; Macías Parra, Mercedes; Marques-Rosa, Fabiano; Catalina Pírez, María; Vázquez-Rivera, Mirella (Taylor and Francis, 2018)
    INTRODUCTION: The Latin American Society of Pediatric Infectious Diseases (SLIPE), with the support of the Americas Health Foundation (AHF), has developed a position paper on varicella prevention in Latin America and ...

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