Publicación: Development and Characterization of a Curcumin-Loaded Alginate-Xanthan Gum Hydrogel for Antibacterial Activity and Controlled Drug Release
| dc.contributor.author | Torres, Lizardo | |
| dc.contributor.author | Cespedes, Sofia | |
| dc.contributor.author | Kim, Suyeon | |
| dc.contributor.author | Nakamatsu, Javier | |
| dc.contributor.author | Obregón Príncipe, Marco | |
| dc.contributor.author | Castillo, Denis | |
| dc.date.accessioned | 2026-05-01T06:26:32Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | This article describes the development and characterization of a curcumin-loaded alginate exanthan gum hydrogel, designed to provide both antibacterial activity and controlled drug release. The hydrogel formulation consisted of 4% (w/v) alginate, 4% (w/v) xanthan gum, and 500 µg/mL of curcumin. Sterilization was achieved through ethanol immersion, UV irradiation, and autoclav- ing, with the latter two methods proving to be the most effective in maintaining long-term sterility. Antibacterial efficacy was tested against Staphylococcus aureus, demonstrating a significant inhibition zone around the hydrogel. The curcumin release profile indicated a sustained release over 72 hours, suggesting its suitability for prolonged antibacterial applications. © 2025 Trans Tech Publications Ltd, All Rights Reserved. | en_US |
| dc.description.sponsorship | This work was funded by the Vicerrectorado de Investigaci\u00F3n at the Pontificia Universidad Cat\u00F3lica del Per\u00FA through grant DGI N\u02DAPI0985 and by the Consejo Nacional de Ciencia, Tecnolog\u00EDa e Innovaci\u00F3n Tecnol\u00F3gica - CONCYTEC - Peru, (N\u00B0 PE501078239-2022-Prociencia). The author(s) thank the Maestr\u00EDa en Ciencia e Ingenier\u00EDa de los Materiales at the Pontificia Universidad Cat\u00F3lica del Per\u00FA for their support. | es_PE |
| dc.identifier.doi | https://doi.org/10.4028/p-vEt8Dm | |
| dc.identifier.scopus | 2-s2.0-105021113060 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/19470 | |
| dc.language.iso | eng | |
| dc.publisher | Trans Tech Publications Ltd | |
| dc.relation.ispartof | urn:issn:0255-5476 | |
| dc.relation.ispartofseries | Materials Science Forum | |
| dc.relation.issn | 0255-5476 | |
| dc.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | alginate | en_US |
| dc.subject | antibacterial activity | en_US |
| dc.subject | curcumin | en_US |
| dc.subject | drug release | en_US |
| dc.subject | hydrogel | en_US |
| dc.subject | xanthan gum | en_US |
| dc.title | Development and Characterization of a Curcumin-Loaded Alginate-Xanthan Gum Hydrogel for Antibacterial Activity and Controlled Drug Release | en_US |
| dc.type | https://purl.org/coar/resource_type/c_3248 | |
| dc.type.local | Capítulo - Parte de Libro | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication |